Protein: RAGE
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)

Gene: RAGE, AGER
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q15109

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001650 - fibrillar center
GO:0001666 - response to hypoxia
GO:0001774 - microglial cell activation
GO:0001914 - regulation of T cell mediated cytotoxicity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380779

S100B
Protein S100-B

3

9

Small-scale

0.861

High

946195

S10AC
Protein S100-A12

2

9

Small-scale

0.768

High

638960

S100P
Protein S100-P

2

9

Small-scale

0.754

High

1067904

TLR9
Toll-like receptor 9

1

11

Small-scale

0.665

High

615216

S10A1
Protein S100-A1

1

9

Small-scale

0.647

High

642944

S10A4
Protein S100-A4

1

9

Small-scale

0.647

High

1067895

RAGE
Advanced glycosylation end product-specific receptor

1

19

Small-scale

0.647

High

449727

HMGB1
High mobility group protein B1

3

4

Small-scale

0.646

High

155360

NRP1
Neuropilin-1

1

8

High-throughput

0.618

High

447037

FGF2
Fibroblast growth factor 2

1

3

Small-scale

0.618

High

508009

FGFR1
Fibroblast growth factor receptor 1

1

20

Small-scale

0.618

High

394738

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.611

High

924585

GRB2
Growth factor receptor-bound protein 2

2

17

High-throughput

0.611

High

983839

KPCZ
Protein kinase C zeta type

1

1

Small-scale

0.586

High

1067896

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

216731

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.573

High

886002

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

1

Small-scale

0.536

High

1067903

MYD88
Myeloid differentiation primary response protein MyD88

1

4

Small-scale

0.536

High

1067905

IRAK4
Interleukin-1 receptor-associated kinase 4

1

1

Small-scale

0.536

High

237597

DIAP1
Protein diaphanous homolog 1

1

5

Small-scale

0.529

High

338449

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.515

High

403887

ITB1
Integrin beta-1

1

10

High-throughput

0.515

High

363598

TTHY
Transthyretin

1

0

Small-scale

0.513

High

1067898

MAPK5
MAP kinase-activated protein kinase 5

1

5

Small-scale

0.495

High

618268

BDNF
Brain-derived neurotrophic factor

1

0

High-throughput

0.493

High

350182

RASK
GTPase KRas

1

20

Small-scale

0.479

High

362469

C1QA
Complement C1q subcomponent subunit A

1

4

Small-scale

0.479

High

362530

C1QB
Complement C1q subcomponent subunit B

1

5

Small-scale

0.479

High

362589

C1QC
Complement C1q subcomponent subunit C

1

5

Small-scale

0.479

High

557699

NCK1
SH2/SH3 adapter protein NCK1

1

14

High-throughput

0.479

High

598941

FPR1
fMet-Leu-Phe receptor

1

4

Small-scale

0.479

High

626516

FPR2
N-formyl peptide receptor 2

1

4

Small-scale

0.479

High

900490

RHOA
Transforming protein RhoA

1

20

Small-scale

0.479

High

1067901

FBXW7
F-box/WD repeat-containing protein 7

1

2

Small-scale

0.479

High

1067899

MIER1
Mesoderm induction early response protein 1

1

1

High-throughput

0.470

High

703386

CSTF2
Cleavage stimulation factor subunit 2

1

5

High-throughput

0.437

High

890163

SC61B
Protein transport protein Sec61 subunit beta

1

3

Small-scale

0.437

High

1047860

CIRBP
Cold-inducible RNA-binding protein

1

5

Small-scale

0.437

High

1067897

TCAM2
TIR domain-containing adapter molecule 2

1

0

Small-scale

0.426

High

1067902

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

0

High-throughput

0.316

High

1067900

CB015
Uncharacterized protein C2orf15

1

0

High-throughput

0.268

Low

1067906

FBX10
F-box only protein 10

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024