Protein: HAND2
Heart- and neural crest derivatives-expressed protein 2 (Class A basic helix-loop-helix protein 26) (bHLHa26) (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND)

Gene: HAND2
Organism: Homo sapiens
Interactions: 29
UniProt ID: P61296

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 - transcription coactivator binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

899129

HTF4
Transcription factor 12

3

20

High-throughput

0.858

High

551106

ITF2
Transcription factor 4

2

20

High-throughput

0.831

High

551490

TFE2
Transcription factor E2-alpha

2

20

Small-scale

0.793

High

899117

HAND2
Heart- and neural crest derivatives-expressed protein 2

1

17

Small-scale

0.647

High

379191

MYCN
N-myc proto-oncogene protein

1

19

High-throughput

0.618

High

224378

RAD21
Double-strand-break repair protein rad21 homolog

2

2

High-throughput

0.601

High

899119

RIPP1
Protein ripply1

2

0

High-throughput

0.580

High

156123

PHX2A
Paired mesoderm homeobox protein 2A

1

11

Small-scale

0.561

High

798825

GATA4
Transcription factor GATA-4

1

9

Small-scale

0.561

High

899123

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

20

High-throughput

0.553

High

899124

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

899133

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

15

High-throughput

0.553

High

899121

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

2

Small-scale

0.527

High

899128

OPTN
Optineurin

1

10

High-throughput

0.515

High

566344

KPCA
Protein kinase C alpha type

1

5

Small-scale

0.501

High

568609

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

3

Small-scale

0.501

High

899118

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.501

High

899131

DNM3L
DNA

1

4

Small-scale

0.501

High

418101

NPM
Nucleophosmin

1

5

Small-scale

0.481

High

422498

CENPB
Major centromere autoantigen B

1

1

Small-scale

0.481

High

899127

CSN5
COP9 signalosome complex subunit 5

1

3

Small-scale

0.481

High

723679

HXD13
Homeobox protein Hox-D13

1

20

Small-scale

0.479

High

899120

SMC1A
Structural maintenance of chromosomes protein 1A

1

6

High-throughput

0.479

High

899125

STAG2
Cohesin subunit SA-2

1

2

High-throughput

0.479

High

899126

STAG1
Cohesin subunit SA-1

1

2

High-throughput

0.479

High

899130

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.479

High

899132

SMC3
Structural maintenance of chromosomes protein 3

1

5

High-throughput

0.479

High

899122

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

2

0

High-throughput

0.316

High


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Last updated: 15 Jul 2024