Protein: ABL2
Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)

Gene: ABL2
Organism: Homo sapiens
Interactions: 110
UniProt ID: P42684

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001784 - phosphotyrosine residue binding
GO:0003785 - actin monomer binding
GO:0004672 - protein kinase activity
GO:0004713 - protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

789043

CRK
Adapter molecule crk

7

20

Small-scale

0.970

High

789094

ABI2
Abl interactor 2

4

20

High-throughput

0.902

High

338083

EGFR
Epidermal growth factor receptor

4

20

High-throughput

0.887

High

209001

NCK2
Cytoplasmic protein NCK2

3

20

High-throughput

0.861

High

337384

ABL1
Tyrosine-protein kinase ABL1

3

19

Small-scale

0.858

High

383673

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

20

Small-scale

0.858

High

789070

CIP4
Cdc42-interacting protein 4

3

6

Small-scale

0.853

High

789054

GRB2
Growth factor receptor-bound protein 2

3

19

Small-scale

0.834

High

557630

NCK1
SH2/SH3 adapter protein NCK1

2

20

High-throughput

0.789

High

601837

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.778

High

789042

ABL2
Tyrosine-protein kinase ABL2

2

19

Small-scale

0.778

High

789067

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

19

High-throughput

0.778

High

776597

STAT3
Signal transducer and activator of transcription 3

2

14

High-throughput

0.767

High

789082

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

19

High-throughput

0.767

High

665558

EPHB2
Ephrin type-B receptor 2

2

20

Small-scale

0.757

High

789056

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.754

High

580953

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

18

High-throughput

0.747

High

789049

EPHA4
Ephrin type-A receptor 4

2

20

High-throughput

0.743

High

738170

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

20

Small-scale

0.724

High

789060

1433F
14-3-3 protein eta

1

20

High-throughput

0.715

High

298959

SRBS2
Sorbin and SH3 domain-containing protein 2

1

20

Small-scale

0.709

High

789065

RIN1
Ras and Rab interactor 1

4

20

Small-scale

0.704

High

442789

HCK
Tyrosine-protein kinase HCK

1

19

High-throughput

0.698

High

789058

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

17

High-throughput

0.698

High

441462

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

499244

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

235483

VINEX
Vinexin

1

20

High-throughput

0.691

High

789044

CRKL
Crk-like protein

1

20

High-throughput

0.691

High

789081

IASPP
RelA-associated inhibitor

1

16

High-throughput

0.691

High

789087

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.691

High

503608

HSP7C
Heat shock cognate 71 kDa protein

4

11

High-throughput

0.691

High

789098

BAG5
BAG family molecular chaperone regulator 5

3

2

High-throughput

0.667

High

452370

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.647

High

789074

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

16

High-throughput

0.647

High

789078

ABI1
Abl interactor 1

1

20

Small-scale

0.647

High

789085

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

12

High-throughput

0.647

High

789071

CDC37
Hsp90 co-chaperone Cdc37

2

12

High-throughput

0.628

High

275550

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

20

High-throughput

0.618

High

384434

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

412070

FYN
Tyrosine-protein kinase Fyn

1

19

High-throughput

0.618

High

507897

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

522840

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

High-throughput

0.618

High

607907

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

616759

JAK1
Tyrosine-protein kinase JAK1

1

19

Small-scale

0.618

High

646706

1433T
14-3-3 protein theta

1

20

High-throughput

0.618

High

655254

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

666033

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.618

High

674354

UFO
Tyrosine-protein kinase receptor UFO

1

20

Small-scale

0.618

High

683185

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.618

High

683884

1433S
14-3-3 protein sigma

1

20

High-throughput

0.618

High

789048

EPHB4
Ephrin type-B receptor 4

1

20

High-throughput

0.618

High

789052

1433G
14-3-3 protein gamma

1

20

High-throughput

0.618

High

789053

1433E
14-3-3 protein epsilon

1

4

High-throughput

0.618

High

789061

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.618

High

789066

SRC8
Src substrate cortactin

1

20

Small-scale

0.618

High

789068

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.618

High

789076

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

789099

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.618

High

789100

NCKP1
Nck-associated protein 1

2

2

High-throughput

0.611

High

373358

CATA
Catalase

1

1

Small-scale

0.578

High

422603

GPX1
Glutathione peroxidase 1

1

1

Small-scale

0.578

High

789088

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

20

Small-scale

0.575

High

789093

CASS4
Cas scaffolding protein family member 4

1

20

Small-scale

0.575

High

156243

PSA7
Proteasome subunit alpha type-7

1

2

Small-scale

0.561

High

349172

RASH
GTPase HRas

1

19

Small-scale

0.554

High

487203

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

323625

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.536

High

431626

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.536

High

437966

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.536

High

789047

HSP72
Heat shock-related 70 kDa protein 2

1

11

High-throughput

0.536

High

789063

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

3

High-throughput

0.536

High

789064

CUL4A
Cullin-4A

2

3

Small-scale

0.533

High

789086

DOK1
Docking protein 1

1

20

Small-scale

0.527

High

789075

FBX38
F-box only protein 38

1

0

High-throughput

0.518

High

789045

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

12

High-throughput

0.501

High

789089

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

6

Small-scale

0.489

High

179022

TNC18
Trinucleotide repeat-containing gene 18 protein

1

8

High-throughput

0.479

High

349949

RASK
GTPase KRas

1

20

High-throughput

0.479

High

443382

VIME
Vimentin

1

8

High-throughput

0.479

High

545245

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

564442

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

610281

CBL
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.479

High

722664

SPRE
Sepiapterin reductase

1

6

High-throughput

0.479

High

781320

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.479

High

789046

PAXI
Paxillin

1

20

High-throughput

0.479

High

789050

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

789051

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

789055

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

789062

BST2
Bone marrow stromal antigen 2

1

1

High-throughput

0.479

High

789079

SCAI
Protein SCAI

1

1

High-throughput

0.479

High

789080

BICD2
Protein bicaudal D homolog 2

1

15

High-throughput

0.479

High

789083

BICD1
Protein bicaudal D homolog 1

1

16

High-throughput

0.479

High

789084

SNX27
Sorting nexin-27

1

14

High-throughput

0.479

High

789091

MED28
Mediator of RNA polymerase II transcription subunit 28

1

8

Small-scale

0.470

High

789059

CAV1
Caveolin-1

1

9

Small-scale

0.457

High

557441

PECA1
Platelet endothelial cell adhesion molecule

1

17

Small-scale

0.445

High

789073

ZMAT1
Zinc finger matrin-type protein 1

1

1

High-throughput

0.439

High

789077

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

789092

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

789097

TF3C4
General transcription factor 3C polypeptide 4

1

2

High-throughput

0.437

High

326943

G6B
Megakaryocyte and platelet inhibitory receptor G6b

1

0

Small-scale

0.426

High

789069

SF01
Splicing factor 1

1

20

High-throughput

0.417

High

789057

MDM2
E3 ubiquitin-protein ligase Mdm2

1

5

Small-scale

0.408

High

789096

SLAF5
SLAM family member 5

1

15

Small-scale

0.407

High

175423

SIVA
Apoptosis regulatory protein Siva

1

0

Small-scale

0.292

High

204301

MS18B
Protein Mis18-beta

1

0

High-throughput

0.282

High

789072

TPD53
Tumor protein D53

1

0

High-throughput

0.282

High

789090

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.282

High

789095

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024