Protein: HIRA
Protein HIRA (TUP1-like enhancer of split protein 1)

Gene: HIRA
Organism: Homo sapiens
Interactions: 113
UniProt ID: P54198

Gene Ontology (top 5):
GO:0000417 - HIR complex
GO:0000785 - chromatin
GO:0001649 - osteoblast differentiation
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

867906

ASF1A
Histone chaperone ASF1A

14

17

Small-scale

0.763

High

867895

UBN1
Ubinuclein-1

8

6

Small-scale

0.755

High

867853

H33
Histone H3.3

7

20

Small-scale

0.742

High

867897

ASF1B
Histone chaperone ASF1B

5

17

Small-scale

0.727

High

867911

CABIN
Calcineurin-binding protein cabin-1

6

7

Small-scale

0.726

High

867850

H31
Histone H3.1

6

20

High-throughput

0.721

High

867861

RBBP4
Histone-binding protein RBBP4

1

17

High-throughput

0.691

High

867877

UBN2
Ubinuclein-2

3

12

Small-scale

0.656

High

867849

UBC9
SUMO-conjugating enzyme UBC9

1

7

Small-scale

0.647

High

867848

H4
Histone H4

3

12

Small-scale

0.640

High

346321

MYC
Myc proto-oncogene protein

3

19

Small-scale

0.633

High

485216

TZAP
Telomere zinc finger-associated protein

2

2

High-throughput

0.628

High

814619

CDX1
Homeobox protein CDX-1

2

2

High-throughput

0.628

High

847989

MECP2
Methyl-CpG-binding protein 2

2

7

High-throughput

0.628

High

867859

SP4
Transcription factor Sp4

2

8

High-throughput

0.628

High

867872

TEAD2
Transcriptional enhancer factor TEF-4

2

2

High-throughput

0.628

High

867873

RBBP7
Histone-binding protein RBBP7

1

18

High-throughput

0.618

High

243346

DNJA2
DnaJ homolog subfamily A member 2

2

11

Small-scale

0.611

High

867880

TLK2
Serine/threonine-protein kinase tousled-like 2

2

6

High-throughput

0.611

High

867856

TFAP4
Transcription factor AP-4

2

0

High-throughput

0.602

High

668539

PML
Protein PML

2

12

Small-scale

0.584

High

867867

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.575

High

369245

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

174746

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

12

Small-scale

0.561

High

552325

RFA2
Replication protein A 32 kDa subunit

1

7

Small-scale

0.561

High

650768

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

Small-scale

0.561

High

157024

AIM2
Interferon-inducible protein AIM2

1

5

High-throughput

0.536

High

536497

IRF2
Interferon regulatory factor 2

1

1

High-throughput

0.536

High

564843

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

796712

RANG
Ran-specific GTPase-activating protein

1

3

High-throughput

0.536

High

801041

KI67
Proliferation marker protein Ki-67

1

14

High-throughput

0.536

High

813268

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

857935

PDX1
Pancreas/duodenum homeobox protein 1

1

2

High-throughput

0.536

High

867854

FOXK2
Forkhead box protein K2

1

10

High-throughput

0.536

High

867857

MEF2A
Myocyte-specific enhancer factor 2A

1

2

High-throughput

0.536

High

867876

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.536

High

867887

ZBT10
Zinc finger and BTB domain-containing protein 10

1

6

High-throughput

0.536

High

867896

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.536

High

867901

DBNL
Drebrin-like protein

1

6

High-throughput

0.536

High

867902

TLK1
Serine/threonine-protein kinase tousled-like 1

1

5

High-throughput

0.536

High

241485

H2B1K
Histone H2B type 1-K

1

13

Small-scale

0.527

High

559030

H15
Histone H1.5

1

7

High-throughput

0.515

High

614282

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

3

High-throughput

0.515

High

867890

NKX31
Homeobox protein Nkx-3.1

1

17

High-throughput

0.515

High

867865

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.513

High

867907

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.513

High

867884

RENT1
Regulator of nonsense transcripts 1

1

6

High-throughput

0.508

High

867904

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

0

Small-scale

0.504

High

867891

HIRP3
HIRA-interacting protein 3

1

3

Small-scale

0.501

High

323659

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

867860

CALD1
Caldesmon

1

18

High-throughput

0.489

High

867864

TRAF1
TNF receptor-associated factor 1

1

3

High-throughput

0.489

High

867870

SRC8
Src substrate cortactin

1

6

High-throughput

0.489

High

867847

H2B1D
Histone H2B type 1-D

1

13

Small-scale

0.481

High

867869

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

15

High-throughput

0.481

High

867885

TRI63
E3 ubiquitin-protein ligase TRIM63

1

10

High-throughput

0.481

High

867892

TRI55
Tripartite motif-containing protein 55

1

17

High-throughput

0.481

High

197681

CRX
Cone-rod homeobox protein

1

9

High-throughput

0.479

High

201279

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

Small-scale

0.479

High

322374

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

13

High-throughput

0.479

High

391612

H2A1B
Histone H2A type 1-B/E

1

11

High-throughput

0.479

High

401694

JUN
Transcription factor Jun

1

14

Small-scale

0.479

High

487260

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

503747

HSP7C
Heat shock cognate 71 kDa protein

1

7

Small-scale

0.479

High

505197

EGR2
E3 SUMO-protein ligase EGR2

1

2

High-throughput

0.479

High

590741

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

624828

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

Small-scale

0.479

High

727491

HNF1B
Hepatocyte nuclear factor 1-beta

1

8

High-throughput

0.479

High

727839

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

782507

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

785346

ELK3
ETS domain-containing protein Elk-3

1

14

High-throughput

0.479

High

814921

LEG7
Galectin-7

1

4

Small-scale

0.479

High

825800

NASP
Nuclear autoantigenic sperm protein

1

4

High-throughput

0.479

High

828179

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

830852

CTCF
Transcriptional repressor CTCF

1

3

Small-scale

0.479

High

832260

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

846728

SMCA2
Probable global transcription activator SNF2L2

1

18

Small-scale

0.479

High

846905

SMCA4
Transcription activator BRG1

1

20

Small-scale

0.479

High

867846

KLF3
Krueppel-like factor 3

1

10

High-throughput

0.479

High

867851

GTF2I
General transcription factor II-I

1

1

Small-scale

0.479

High

867852

DCD
Dermcidin

1

2

Small-scale

0.479

High

867858

DSG1
Desmoglein-1

1

3

Small-scale

0.479

High

867862

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

3

Small-scale

0.479

High

867863

TP53B
TP53-binding protein 1

1

11

High-throughput

0.479

High

867866

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

2

High-throughput

0.479

High

867868

CUL3
Cullin-3

1

16

Small-scale

0.479

High

867871

MEF2D
Myocyte-specific enhancer factor 2D

1

1

Small-scale

0.479

High

867874

F263
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

1

1

Small-scale

0.479

High

867875

RIF1
Telomere-associated protein RIF1

1

10

High-throughput

0.479

High

867878

H32
Histone H3.2

1

20

Small-scale

0.479

High

867879

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

867883

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

867889

ELF4
ETS-related transcription factor Elf-4

1

14

High-throughput

0.479

High

867893

S10AE
Protein S100-A14

1

1

High-throughput

0.479

High

867900

LHX3
LIM/homeobox protein Lhx3

1

1

High-throughput

0.479

High

867903

BAG5
BAG family molecular chaperone regulator 5

1

2

Small-scale

0.479

High

867905

RUVB1
RuvB-like 1

1

5

Small-scale

0.479

High

867910

ETV7
Transcription factor ETV7

1

10

High-throughput

0.479

High

158764

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

345066

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

867855

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

867881

CDAN1
Codanin-1

1

0

High-throughput

0.458

High

867908

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.458

High

867909

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

Small-scale

0.458

High

321025

PTBP3
Polypyrimidine tract-binding protein 3

1

10

High-throughput

0.445

High

867888

CDC5L
Cell division cycle 5-like protein

1

13

High-throughput

0.445

High

867898

GRHL1
Grainyhead-like protein 1 homolog

1

2

High-throughput

0.445

High

608855

SPR1B
Cornifin-B

1

1

High-throughput

0.437

High

867894

XAGE1
X antigen family member 1

2

0

High-throughput

0.313

High

306936

CSPG5
Chondroitin sulfate proteoglycan 5

1

0

High-throughput

0.279

Low

867882

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

867886

TIFA
TRAF-interacting protein with FHA domain-containing protein A

1

0

Small-scale

0.249

Low

867899

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024