Protein: ITAM
Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b)

Gene: ITAM, ITGAM
Organism: Homo sapiens
Interactions: 69
UniProt ID: P11215

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001774 - microglial cell activation
GO:0001851 - complement component C3b binding
GO:0002430 - complement receptor mediated signaling pathway
GO:0002931 - response to ischemia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396607

ITB2
Integrin beta-2

3

20

Small-scale

0.839

High

506141

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.783

High

506098

SPI1
Transcription factor PU.1

5

2

Small-scale

0.706

High

399957

ICAM1
Intercellular adhesion molecule 1

1

7

Small-scale

0.647

High

506132

JAM3
Junctional adhesion molecule C

1

3

Small-scale

0.647

High

198385

KLK10
Kallikrein-10

1

13

High-throughput

0.618

High

344628

CO3
Complement C3

1

5

Small-scale

0.618

High

506100

PRTN3
Myeloblastin

1

13

Small-scale

0.618

High

506101

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

8

Small-scale

0.618

High

506136

CLC4M
C-type lectin domain family 4 member M

1

6

Small-scale

0.618

High

506096

MUC1
Mucin-1

2

1

High-throughput

0.606

High

506102

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

5

High-throughput

0.606

High

506104

CXA8
Gap junction alpha-8 protein

2

3

High-throughput

0.606

High

506131

REEP2
Receptor expression-enhancing protein 2

2

1

High-throughput

0.606

High

506105

BAP31
B-cell receptor-associated protein 31

1

1

Small-scale

0.589

High

506094

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

506103

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.580

High

506108

CLRN1
Clarin-1

2

0

High-throughput

0.580

High

506111

AQP6
Aquaporin-6

2

0

High-throughput

0.580

High

506113

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.580

High

506115

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.580

High

506120

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.580

High

506123

SYT2
Synaptotagmin-2

2

0

High-throughput

0.580

High

506142

DKK4
Dickkopf-related protein 4

2

0

High-throughput

0.580

High

506099

PTN
Pleiotrophin

1

1

Small-scale

0.554

High

434806

CXB1
Gap junction beta-1 protein

2

3

High-throughput

0.553

High

506114

AR13B
ADP-ribosylation factor-like protein 13B

2

12

High-throughput

0.553

High

506119

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

2

High-throughput

0.553

High

506121

KASH5
Protein KASH5

2

3

High-throughput

0.553

High

506128

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

3

High-throughput

0.553

High

506137

REEP4
Receptor expression-enhancing protein 4

2

1

High-throughput

0.553

High

506145

TMX2
Thioredoxin-related transmembrane protein 2

2

1

High-throughput

0.553

High

506133

TX101
Testis-expressed protein 101

1

4

High-throughput

0.536

High

506143

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

1

High-throughput

0.536

High

506095

VAV
Proto-oncogene vav

1

2

Small-scale

0.515

High

181974

GPR42
G-protein coupled receptor 42

1

3

High-throughput

0.515

High

506106

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

Small-scale

0.493

High

506130

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.489

High

506146

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

5

Small-scale

0.481

High

506110

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.480

High

226359

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

361438

APOE
Apolipoprotein E

1

1

Small-scale

0.479

High

394007

A4
Amyloid-beta precursor protein

1

5

Small-scale

0.479

High

434911

SP1
Transcription factor Sp1

1

3

Small-scale

0.479

High

441006

CD14
Monocyte differentiation antigen CD14

1

1

Small-scale

0.479

High

506097

LEG3
Galectin-3

1

20

Small-scale

0.479

High

506109

SP3
Transcription factor Sp3

1

3

Small-scale

0.479

High

506112

BGH3
Transforming growth factor-beta-induced protein ig-h3

1

0

Small-scale

0.458

High

506122

CD177
CD177 antigen

1

4

Small-scale

0.445

High

359600

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.439

High

506125

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.437

High

506135

SHRPN
Sharpin

1

7

Small-scale

0.408

High

157517

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.316

High

170780

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.316

High

326972

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.316

High

506107

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

2

0

High-throughput

0.316

High

506117

GORAB
RAB6-interacting golgin

2

0

High-throughput

0.316

High

506118

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.316

High

506124

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

506129

RUSF1
RUS family member 1

2

0

High-throughput

0.316

High

506134

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.316

High

506138

CERS4
Ceramide synthase 4

2

0

High-throughput

0.316

High

506139

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

506140

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

506144

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High

506126

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

506116

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

506127

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.251

Low

224282

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024