Protein: FYV1
1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1)

Gene: FYV1, PIKFYVE
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q9Y2I7

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000285 - 1-phosphatidylinositol-3-phosphate 5-kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1310831

WDR83
WD repeat domain-containing protein 83

3

20

High-throughput

0.847

High

997483

VAC14
Protein VAC14 homolog

5

3

Small-scale

0.725

High

1267345

FIG4
Polyphosphoinositide phosphatase

5

3

Small-scale

0.712

High

1146980

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.618

High

556723

ANK1
Ankyrin-1

2

2

High-throughput

0.611

High

1191987

RABEK
Rab9 effector protein with kelch motifs

1

12

Small-scale

0.586

High

396085

A4
Amyloid-beta precursor protein

2

0

Small-scale

0.577

High

418807

NPM
Nucleophosmin

1

1

High-throughput

0.515

High

935391

H31
Histone H3.1

1

5

Small-scale

0.512

High

960350

CDK5
Cyclin-dependent kinase 5

1

18

Small-scale

0.501

High

1282771

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

1

0

High-throughput

0.493

High

385752

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

499414

ESTD
S-formylglutathione hydrolase

1

1

High-throughput

0.479

High

527896

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

592071

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.479

High

592595

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

813862

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.479

High

845363

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

845814

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

1081178

CCDC6
Coiled-coil domain-containing protein 6

1

9

High-throughput

0.479

High

1172339

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1290104

RNF31
E3 ubiquitin-protein ligase RNF31

1

8

High-throughput

0.479

High

1335405

RHOF
Rho-related GTP-binding protein RhoF

1

2

High-throughput

0.479

High

1357932

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

925747

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.458

High

1044471

PTC1
Protein patched homolog 1

1

0

Small-scale

0.458

High

1152206

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1188453

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1266605

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1284679

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.458

High

1169449

NBEL2
Neurobeachin-like protein 2

1

20

High-throughput

0.445

High

158692

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

1

High-throughput

0.437

High

206193

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

781491

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.437

High

800557

CBX5
Chromobox protein homolog 5

1

9

Small-scale

0.437

High

1159476

FBX42
F-box only protein 42

1

13

High-throughput

0.437

High

378466

LCAT
Phosphatidylcholine-sterol acyltransferase

1

1

Small-scale

0.407

High

1377277

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

1189068

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1347736

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

1295620

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024