Protein: CCND3
G1/S-specific cyclin-D3

Gene: CCND3
Organism: Homo sapiens
Interactions: 79
UniProt ID: P30281

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001934 - positive regulation of protein phosphorylation
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

515348

CDK4
Cyclin-dependent kinase 4

28

20

Small-scale

0.993

High

673141

CDK6
Cyclin-dependent kinase 6

24

20

Small-scale

0.992

High

673127

CDN1A
Cyclin-dependent kinase inhibitor 1

20

20

Small-scale

0.991

High

673130

CDN1B
Cyclin-dependent kinase inhibitor 1B

12

20

Small-scale

0.981

High

673142

CDK5
Cyclin-dependent kinase 5

8

20

High-throughput

0.973

High

625156

CDK2
Cyclin-dependent kinase 2

9

20

Small-scale

0.972

High

414765

CDK1
Cyclin-dependent kinase 1

4

20

High-throughput

0.903

High

673132

CDN1C
Cyclin-dependent kinase inhibitor 1C

4

20

High-throughput

0.903

High

596721

CD11B
Cyclin-dependent kinase 11B

2

20

Small-scale

0.817

High

673140

CDK3
Cyclin-dependent kinase 3

2

20

High-throughput

0.783

High

673143

CDK16
Cyclin-dependent kinase 16

2

20

High-throughput

0.783

High

673144

CDK18
Cyclin-dependent kinase 18

2

20

High-throughput

0.783

High

300627

CDK14
Cyclin-dependent kinase 14

1

20

Small-scale

0.766

High

673145

RBL2
Retinoblastoma-like protein 2

5

20

Small-scale

0.723

High

673164

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

4

0

High-throughput

0.668

High

673129

CDN2C
Cyclin-dependent kinase 4 inhibitor C

3

12

High-throughput

0.667

High

673158

CBP
CREB-binding protein

3

9

High-throughput

0.667

High

673178

KLK5
Kallikrein-5

3

2

High-throughput

0.667

High

414188

RB
Retinoblastoma-associated protein

3

20

Small-scale

0.647

High

666440

RABP2
Cellular retinoic acid-binding protein 2

3

0

Small-scale

0.646

High

509912

VDR
Vitamin D3 receptor

2

8

Small-scale

0.633

High

673176

ATF5
Cyclic AMP-dependent transcription factor ATF-5

2

1

Small-scale

0.633

High

673152

MK06
Mitogen-activated protein kinase 6

1

19

High-throughput

0.621

High

517081

PCNA
Proliferating cell nuclear antigen

2

7

Small-scale

0.619

High

673147

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.618

High

673159

DTBP1
Dysbindin

2

3

Small-scale

0.614

High

673173

EIF3K
Eukaryotic translation initiation factor 3 subunit K

2

0

Small-scale

0.614

High

673153

MCM10
Protein MCM10 homolog

2

1

High-throughput

0.611

High

159902

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

1

High-throughput

0.606

High

673134

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

12

High-throughput

0.606

High

673175

STAP1
Signal-transducing adaptor protein 1

2

0

High-throughput

0.602

High

673172

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.601

High

673154

CCD13
Coiled-coil domain-containing protein 13

2

0

High-throughput

0.580

High

673165

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.580

High

673171

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.580

High

487910

RARA
Retinoic acid receptor alpha

1

4

Small-scale

0.573

High

673150

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

9

Small-scale

0.561

High

215590

AKAP8
A-kinase anchor protein 8

1

4

Small-scale

0.552

High

486748

MYB
Transcriptional activator Myb

1

5

High-throughput

0.541

High

632200

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.541

High

673177

AMOL2
Angiomotin-like protein 2

1

1

High-throughput

0.536

High

673133

ETV1
ETS translocation variant 1

1

0

High-throughput

0.518

High

673167

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

1

0

High-throughput

0.518

High

673126

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

18

High-throughput

0.515

High

673136

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

18

High-throughput

0.515

High

571088

EGLN
Endoglin

1

0

High-throughput

0.513

High

673149

VGLL4
Transcription cofactor vestigial-like protein 4

1

0

High-throughput

0.513

High

394183

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

658316

DPOD1
DNA polymerase delta catalytic subunit

1

6

Small-scale

0.501

High

673151

NCOA2
Nuclear receptor coactivator 2

1

5

Small-scale

0.501

High

327957

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

1

High-throughput

0.494

High

363998

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.481

High

548866

NDKA
Nucleoside diphosphate kinase A

1

1

High-throughput

0.481

High

673137

PRS4
26S proteasome regulatory subunit 4

1

4

High-throughput

0.481

High

673138

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

1

High-throughput

0.481

High

673148

FHL3
Four and a half LIM domains protein 3

1

1

High-throughput

0.481

High

673161

QKI
KH domain-containing RNA-binding protein QKI

1

1

High-throughput

0.481

High

226622

PRKN
E3 ubiquitin-protein ligase parkin

1

9

Small-scale

0.479

High

524540

LYL1
Protein lyl-1

1

4

High-throughput

0.479

High

533792

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

2

Small-scale

0.479

High

556786

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.479

High

673131

TSC2
Tuberin

1

5

Small-scale

0.479

High

673135

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

18

High-throughput

0.479

High

673139

RBX1
E3 ubiquitin-protein ligase RBX1

1

5

Small-scale

0.479

High

673166

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

7

Small-scale

0.479

High

673174

HERC5
E3 ISG15--protein ligase HERC5

1

5

Small-scale

0.479

High

673128

CASP2
Caspase-2

1

0

Small-scale

0.460

High

673160

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.460

High

673162

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.460

High

673170

SHLB2
Endophilin-B2

1

0

High-throughput

0.460

High

500730

CLUS
Clusterin

1

0

High-throughput

0.458

High

673157

FBH1
F-box DNA helicase 1

1

0

Small-scale

0.458

High

673163

ZNF2
Zinc finger protein 2

1

0

High-throughput

0.458

High

673169

NPDC1
Neural proliferation differentiation and control protein 1

1

2

Small-scale

0.457

High

673146

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.457

High

673155

TEX11
Testis-expressed protein 11

1

1

High-throughput

0.439

High

673156

MNS1
Meiosis-specific nuclear structural protein 1

2

0

High-throughput

0.316

High

673125

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.282

High

673168

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024