Protein: GFI1
Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163)

Gene: GFI1
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q99684

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1305609

PRDM5
PR domain zinc finger protein 5

2

13

Small-scale

0.781

High

1024299

ZBT17
Zinc finger and BTB domain-containing protein 17

1

19

Small-scale

0.747

High

835967

GSK3B
Glycogen synthase kinase-3 beta

1

1

Small-scale

0.647

High

160735

AURKA
Aurora kinase A

1

3

High-throughput

0.618

High

485190

ZSC22
Zinc finger and SCAN domain-containing protein 22

1

19

Small-scale

0.590

High

1102530

ZXDC
Zinc finger protein ZXDC

1

17

Small-scale

0.590

High

1305612

PIAS3
E3 SUMO-protein ligase PIAS3

1

2

Small-scale

0.586

High

1270404

HDAC2
Histone deacetylase 2

2

8

Small-scale

0.584

High

572573

SPI1
Transcription factor PU.1

1

4

Small-scale

0.578

High

312652

ARI2
E3 ubiquitin-protein ligase ARIH2

1

15

Small-scale

0.573

High

1024508

CAF1A
Chromatin assembly factor 1 subunit A

1

1

Small-scale

0.573

High

930368

UBC9
SUMO-conjugating enzyme UBC9

2

1

Small-scale

0.565

High

1231848

PIAS4
E3 SUMO-protein ligase PIAS4

2

2

Small-scale

0.565

High

987461

MTG8
Protein CBFA2T1

1

1

Small-scale

0.561

High

1281342

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.561

High

1038663

HDAC1
Histone deacetylase 1

1

8

Small-scale

0.554

High

978868

TF65
Transcription factor p65

1

1

Small-scale

0.534

High

1296404

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

11

Small-scale

0.534

High

1264790

TITIN
Titin

1

2

Small-scale

0.528

High

1305610

PICK1
PRKCA-binding protein

1

6

High-throughput

0.508

High

1271128

N42L2
NEDD4-binding protein 2-like 2

1

0

Small-scale

0.484

High

232461

KDM1A
Lysine-specific histone demethylase 1A

1

7

Small-scale

0.479

High

347697

MYC
Myc proto-oncogene protein

1

3

Small-scale

0.479

High

387376

P53
Cellular tumor antigen p53

1

6

Small-scale

0.479

High

542759

ETS2
Protein C-ets-2

1

2

Small-scale

0.479

High

758317

CDN1A
Cyclin-dependent kinase inhibitor 1

1

2

Small-scale

0.479

High

831629

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

1041163

CUL1
Cullin-1

1

20

Small-scale

0.479

High

1259755

U2AF4
Splicing factor U2AF 26 kDa subunit

1

1

Small-scale

0.479

High

1305608

ANM1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.479

High

1305611

RCOR1
REST corepressor 1

1

6

Small-scale

0.479

High

439087

ELNE
Neutrophil elastase

1

0

Small-scale

0.458

High

969062

GCYB1
Guanylate cyclase soluble subunit beta-1

1

0

Small-scale

0.458

High

1071527

E2F5
Transcription factor E2F5

1

0

Small-scale

0.458

High

517424

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.457

High

643393

HMGB2
High mobility group protein B2

1

7

Small-scale

0.457

High

1071981

PCBP1
Poly(rC)-binding protein 1

1

1

Small-scale

0.457

High

602142

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

Small-scale

0.438

High

912366

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

Small-scale

0.438

High

178256

IPO8
Importin-8

1

20

Small-scale

0.417

High

560366

EPB42
Protein 4.2

1

1

Small-scale

0.417

High

724390

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

20

Small-scale

0.417

High

1114338

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

18

Small-scale

0.417

High

176845

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

Small-scale

0.238

Low

887935

CD81
CD81 antigen

1

0

Small-scale

0.238

Low

893133

RS20
Small ribosomal subunit protein uS10

1

0

Small-scale

0.238

Low

1223320

SYTL1
Synaptotagmin-like protein 1

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024