Protein: G6PD
Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49)

Gene: G6PD
Organism: Homo sapiens
Interactions: 101
UniProt ID: P11413

Gene Ontology (top 5):
GO:0004345 - glucose-6-phosphate dehydrogenase activity
GO:0005536 - D-glucose binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006006 - glucose metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509204

G6PD
Glucose-6-phosphate 1-dehydrogenase

3

5

Small-scale

0.845

High

503325

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.585

High

226366

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

397130

KPCG
Protein kinase C gamma type

2

1

High-throughput

0.571

High

509226

KPCE
Protein kinase C epsilon type

2

1

High-throughput

0.571

High

509258

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.571

High

509266

SH3G3
Endophilin-A3

2

1

High-throughput

0.571

High

345792

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

509268

ACE2
Angiotensin-converting enzyme 2

2

0

Small-scale

0.559

High

498194

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.547

High

509223

GRB2
Growth factor receptor-bound protein 2

2

0

High-throughput

0.547

High

509228

CAV1
Caveolin-1

2

0

High-throughput

0.547

High

509276

SHOC2
Leucine-rich repeat protein SHOC-2

2

0

High-throughput

0.547

High

330827

PAK4
Serine/threonine-protein kinase PAK 4

1

0

Small-scale

0.537

High

509233

MTMR2
Myotubularin-related protein 2

1

1

High-throughput

0.536

High

388184

HSPB1
Heat shock protein beta-1

1

1

Small-scale

0.515

High

180677

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.513

High

362749

FINC
Fibronectin

1

0

High-throughput

0.513

High

509210

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.513

High

509225

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.513

High

509241

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

509253

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

509259

COMD1
COMM domain-containing protein 1

1

0

High-throughput

0.513

High

509279

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

509254

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

0

Small-scale

0.493

High

509220

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

301575

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

368883

ESR1
Estrogen receptor

1

1

High-throughput

0.479

High

495448

THIO
Thioredoxin

1

2

Small-scale

0.479

High

509248

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

509252

MTMRD
Myotubularin-related protein 13

1

1

High-throughput

0.479

High

509255

DDX60
Probable ATP-dependent RNA helicase DDX60

1

1

High-throughput

0.479

High

509263

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

165915

PER2
Period circadian protein homolog 2

1

0

Small-scale

0.458

High

322118

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

324196

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

351912

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

352461

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

373342

CATA
Catalase

1

0

High-throughput

0.458

High

384171

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

393000

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

509207

VATB2
V-type proton ATPase subunit B, brain isoform

1

0

High-throughput

0.458

High

509212

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

509213

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

509214

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

509215

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

509216

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

509217

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

509218

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.458

High

509219

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

509221

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

509222

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

509224

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

509227

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

0

High-throughput

0.458

High

509229

PUR1
Amidophosphoribosyltransferase

1

0

High-throughput

0.458

High

509230

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

509231

TNK1
Non-receptor tyrosine-protein kinase TNK1

1

0

High-throughput

0.458

High

509232

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

509234

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.458

High

509235

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

509236

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

509237

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

509238

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

509239

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.458

High

509242

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

509243

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

509244

CDC73
Parafibromin

1

0

High-throughput

0.458

High

509246

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

509250

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

509256

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

509257

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

509260

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

509261

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

509262

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

509264

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.458

High

509269

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

509271

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

509273

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.458

High

509274

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

509275

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

Small-scale

0.458

High

509209

GRN
Progranulin

1

1

High-throughput

0.445

High

204975

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

509205

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

509211

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

496174

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

509267

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

High-throughput

0.328

High

509272

CAH10
Carbonic anhydrase-related protein 10

2

0

High-throughput

0.318

High

509245

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.279

Low

509206

H12
Histone H1.2

1

0

High-throughput

0.269

Low

243849

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

329288

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

509208

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

509240

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

509249

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

509251

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

509265

MYDGF
Myeloid-derived growth factor

1

0

High-throughput

0.249

Low

509270

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.249

Low

509277

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

509247

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

509278

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024