Protein: AGTR1
Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor)

Gene: AGTR1
Organism: Homo sapiens
Interactions: 97
UniProt ID: P30556

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001596 - angiotensin type I receptor activity
GO:0001822 - kidney development
GO:0002018 - renin-angiotensin regulation of aldosterone production
GO:0002034 - maintenance of blood vessel diameter homeostasis by renin-angiotensin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674827

ARRB2
Beta-arrestin-2

4

13

Small-scale

0.898

High

674830

APJ
Apelin receptor

2

16

Small-scale

0.789

High

674832

PF2R
Prostaglandin F2-alpha receptor

1

20

Small-scale

0.756

High

674834

ARRB1
Beta-arrestin-1

2

13

Small-scale

0.754

High

673750

BKRB2
B2 bradykinin receptor

1

18

High-throughput

0.698

High

674843

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

13

High-throughput

0.698

High

240872

S19A2
Thiamine transporter 1

3

6

High-throughput

0.667

High

619202

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

20

High-throughput

0.667

High

674833

SC6A8
Sodium- and chloride-dependent creatine transporter 1

3

4

High-throughput

0.667

High

674839

AT12A
Potassium-transporting ATPase alpha chain 2

3

20

High-throughput

0.667

High

674844

CAV1
Caveolin-1

3

4

High-throughput

0.667

High

674851

AT2B3
Plasma membrane calcium-transporting ATPase 3

3

20

High-throughput

0.667

High

373759

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

Small-scale

0.665

High

658806

MK01
Mitogen-activated protein kinase 1

1

4

Small-scale

0.665

High

626625

ARBK1
Beta-adrenergic receptor kinase 1

1

13

Small-scale

0.618

High

674828

GRK5
G protein-coupled receptor kinase 5

1

13

Small-scale

0.618

High

674831

5HT2B
5-hydroxytryptamine receptor 2B

1

18

Small-scale

0.618

High

674835

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

15

Small-scale

0.618

High

326034

TSN15
Tetraspanin-15

2

20

High-throughput

0.611

High

565340

TMM11
Transmembrane protein 11, mitochondrial

2

4

High-throughput

0.611

High

592122

RAB5A
Ras-related protein Rab-5A

2

4

Small-scale

0.595

High

674875

ACE2
Angiotensin-converting enzyme 2

2

2

Small-scale

0.595

High

674891

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.584

High

393419

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.582

High

674858

CERS6
Ceramide synthase 6

1

15

High-throughput

0.582

High

674841

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.553

High

200014

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

1

1

High-throughput

0.541

High

253286

PLCH2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2

1

1

High-throughput

0.541

High

276145

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

5

High-throughput

0.541

High

306986

RTN3
Reticulon-3

1

9

High-throughput

0.541

High

502891

CD37
Leukocyte antigen CD37

1

20

High-throughput

0.541

High

556590

CBR1
Carbonyl reductase [NADPH] 1

1

3

High-throughput

0.541

High

616743

JAK1
Tyrosine-protein kinase JAK1

1

18

High-throughput

0.541

High

646659

1433T
14-3-3 protein theta

1

7

High-throughput

0.541

High

674842

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.541

High

674847

SERC3
Serine incorporator 3

1

3

High-throughput

0.541

High

674854

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.541

High

674868

AP2M1
AP-2 complex subunit mu

1

3

High-throughput

0.541

High

674870

FNBP1
Formin-binding protein 1

1

1

High-throughput

0.541

High

674873

GDIR3
Rho GDP-dissociation inhibitor 3

1

2

High-throughput

0.541

High

674877

RBNS5
Rabenosyn-5

1

4

High-throughput

0.541

High

674878

GHITM
Growth hormone-inducible transmembrane protein

1

2

High-throughput

0.541

High

674882

AT131
Endoplasmic reticulum transmembrane helix translocase

1

20

High-throughput

0.541

High

674884

T161A
Transmembrane protein 161A

1

5

High-throughput

0.541

High

674888

ABI3
ABI gene family member 3

1

5

High-throughput

0.541

High

674889

SAE1
SUMO-activating enzyme subunit 1

1

1

High-throughput

0.541

High

674890

ADDG
Gamma-adducin

1

2

High-throughput

0.541

High

674893

LZTS1
Leucine zipper putative tumor suppressor 1

1

3

High-throughput

0.541

High

674894

NPTN
Neuroplastin

1

4

High-throughput

0.541

High

278742

DNJC8
DnaJ homolog subfamily C member 8

1

2

High-throughput

0.532

High

674838

OAZ1
Ornithine decarboxylase antizyme 1

1

1

High-throughput

0.532

High

674837

MOT1
Monocarboxylate transporter 1

1

0

High-throughput

0.518

High

674850

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.518

High

674860

PPR3F
Protein phosphatase 1 regulatory subunit 3F

1

0

High-throughput

0.518

High

674862

CCD25
Coiled-coil domain-containing protein 25

1

0

High-throughput

0.518

High

674869

TMM80
Transmembrane protein 80

1

0

High-throughput

0.518

High

674848

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.514

High

674857

ATRAP
Type-1 angiotensin II receptor-associated protein

1

2

Small-scale

0.501

High

166499

NACAD
NAC-alpha domain-containing protein 1

1

3

High-throughput

0.494

High

401240

7B2
Neuroendocrine protein 7B2

1

1

High-throughput

0.494

High

565879

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.494

High

603114

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.494

High

674852

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

1

High-throughput

0.494

High

674876

BRD8
Bromodomain-containing protein 8

1

1

High-throughput

0.494

High

674881

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

1

2

High-throughput

0.494

High

674885

FA13B
Protein FAM13B

1

3

High-throughput

0.494

High

674887

JKAMP
JNK1/MAPK8-associated membrane protein

1

1

High-throughput

0.494

High

674892

NDRG2
Protein NDRG2

1

4

High-throughput

0.494

High

238366

JAK2
Tyrosine-protein kinase JAK2

1

16

Small-scale

0.479

High

344363

ANGT
Angiotensinogen

1

12

Small-scale

0.479

High

591749

RAB4A
Ras-related protein Rab-4A

1

3

Small-scale

0.479

High

674829

PGH2
Prostaglandin G/H synthase 2

1

1

Small-scale

0.479

High

674836

RAB7A
Ras-related protein Rab-7a

1

3

Small-scale

0.479

High

674880

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

1

1

High-throughput

0.479

High

674845

VAC14
Protein VAC14 homolog

1

7

High-throughput

0.470

High

674871

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.458

High

580943

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

Small-scale

0.445

High

674849

CNCG
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

1

1

High-throughput

0.439

High

674853

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

5

High-throughput

0.437

High

674863

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

3

High-throughput

0.437

High

674866

SETD7
Histone-lysine N-methyltransferase SETD7

1

3

High-throughput

0.437

High

674883

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

3

High-throughput

0.437

High

208245

DCX
Neuronal migration protein doublecortin

2

0

High-throughput

0.328

High

237650

SEP15
Selenoprotein F

1

0

High-throughput

0.282

High

674846

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

0

High-throughput

0.282

High

674856

K0930
Uncharacterized protein KIAA0930

1

0

High-throughput

0.282

High

674859

LCNL1
Lipocalin-like 1 protein

1

0

High-throughput

0.282

High

674861

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.282

High

674864

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.282

High

674865

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.282

High

674867

BAALC
Brain and acute leukemia cytoplasmic protein

1

0

High-throughput

0.282

High

674872

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.282

High

674874

DBND2
Dysbindin domain-containing protein 2

1

0

High-throughput

0.282

High

674879

CUED2
CUE domain-containing protein 2

1

0

High-throughput

0.282

High

674886

SPG21
Maspardin

1

0

High-throughput

0.282

High

674840

RB11A
Ras-related protein Rab-11A

1

0

Small-scale

0.249

Low

674855

THOC7
THO complex subunit 7 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024