Protein: TRM1
tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)

Gene: TRM1, TRMT1
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q9NXH9

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002940 - tRNA N2-guanine methylation
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796355

MAGAB
Melanoma-associated antigen 11

5

2

High-throughput

0.725

High

1347979

PUF60
Poly(U)-binding-splicing factor PUF60

1

1

High-throughput

0.691

High

1221481

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.631

High

1128275

SYAM
Alanine--tRNA ligase, mitochondrial

3

0

High-throughput

0.622

High

885912

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1293307

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.602

High

1173365

RFPLB
Ret finger protein-like 4B

2

0

High-throughput

0.585

High

228891

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

999145

EP300
Histone acetyltransferase p300

2

2

High-throughput

0.584

High

1198543

DPP9
Dipeptidyl peptidase 9

2

0

High-throughput

0.576

High

1347977

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

2

0

High-throughput

0.576

High

1347987

LIPG
Endothelial lipase

2

1

High-throughput

0.574

High

1347985

HEMK1
MTRF1L release factor glutamine methyltransferase

2

1

High-throughput

0.549

High

869763

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.543

High

529802

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

177390

HDAC3
Histone deacetylase 3

1

0

High-throughput

0.513

High

180096

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

258224

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

282158

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

1

0

High-throughput

0.513

High

971382

H11
Histone H1.1

1

0

High-throughput

0.513

High

1024425

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.513

High

1046600

TBB2A
Tubulin beta-2A chain

1

0

High-throughput

0.513

High

1069234

TCAL1
Transcription elongation factor A protein-like 1

1

0

High-throughput

0.513

High

1334669

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

1347978

SENP1
Sentrin-specific protease 1

1

0

High-throughput

0.513

High

1347981

NOCT
Nocturnin

1

0

High-throughput

0.513

High

1347988

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.513

High

348058

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

500161

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

553888

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

652427

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

721612

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

780208

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

906166

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.479

High

1042671

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1064780

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1075644

TRBP2
RISC-loading complex subunit TARBP2

1

3

High-throughput

0.479

High

1080404

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

Small-scale

0.479

High

1203520

SKAP1
Src kinase-associated phosphoprotein 1

1

2

High-throughput

0.479

High

440771

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

504859

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

909225

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

981460

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1020591

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1029948

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1066778

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1281862

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1346501

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1347983

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

1347989

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

610785

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

1

High-throughput

0.445

High

352281

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

1171994

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1263112

LIPH
Lipase member H

1

1

High-throughput

0.437

High

1316772

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1331456

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

167291

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.426

High

803259

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.426

High

847906

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.426

High

1038934

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

0

High-throughput

0.426

High

1051695

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.426

High

1161454

BORA
Protein aurora borealis

1

0

High-throughput

0.426

High

1301289

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.426

High

1309515

TBA1C
Tubulin alpha-1C chain

1

0

High-throughput

0.426

High

1347984

MTO1
Protein MTO1 homolog, mitochondrial

1

0

High-throughput

0.426

High

1064975

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.407

High

1130660

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.407

High

1327257

CLPB
Mitochondrial disaggregase

1

2

High-throughput

0.407

High

1232975

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

2

0

High-throughput

0.313

High

1241811

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

2

0

High-throughput

0.313

High

261918

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.279

Low

311772

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.279

Low

1242891

CHDH
Choline dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1347980

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.279

Low

1347982

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.279

Low

1347986

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

1125781

RNS10
Inactive ribonuclease-like protein 10

1

0

High-throughput

0.269

Low

486665

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

867376

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.232

Low

1242014

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.232

Low

1344771

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024