Protein: WWTR1
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)

Gene: WWTR1
Organism: Mus musculus
Interactions: 36
UniProt ID: Q9EPK5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001649 - osteoblast differentiation
GO:0001894 - tissue homeostasis
GO:0001933 - negative regulation of protein phosphorylation
GO:0003015 - heart process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

809079

YAP1
Transcriptional coactivator YAP1

2

18

Small-scale

0.776

High

1322234

WWTR1
WW domain-containing transcription regulator protein 1

1

18

Small-scale

0.665

High

996452

RUNX2
Runt-related transcription factor 2

2

19

Small-scale

0.584

High

851300

NEK1
Serine/threonine-protein kinase Nek1

1

20

Small-scale

0.561

High

817006

TEAD2
Transcriptional enhancer factor TEF-4

1

19

High-throughput

0.541

High

936316

TEAD3
Transcriptional enhancer factor TEF-5

1

19

High-throughput

0.541

High

1143754

TEAD4
Transcriptional enhancer factor TEF-3

1

19

High-throughput

0.541

High

1208284

ERCC8
DNA excision repair protein ERCC-8

1

10

High-throughput

0.541

High

1322238

TLE6
Transducin-like enhancer protein 6

1

9

High-throughput

0.541

High

193195

AXIN1
Axin-1

1

5

Small-scale

0.536

High

1266186

CERS2
Ceramide synthase 2

1

3

High-throughput

0.494

High

1322069

CERS5
Ceramide synthase 5

1

3

High-throughput

0.494

High

627511

NECD
Necdin

1

7

Small-scale

0.481

High

671381

TEAD1
Transcriptional enhancer factor TEF-1

1

19

High-throughput

0.481

High

192466

PKD2
Polycystin-2

1

13

Small-scale

0.479

High

623702

PAX3
Paired box protein Pax-3

1

4

Small-scale

0.479

High

740725

PPARG
Peroxisome proliferator-activated receptor gamma

1

11

Small-scale

0.479

High

799604

CBP
Histone lysine acetyltransferase CREBBP

1

10

Small-scale

0.479

High

910339

1433E
14-3-3 protein epsilon

1

14

Small-scale

0.479

High

933145

1433T
14-3-3 protein theta

1

20

Small-scale

0.479

High

1112928

FBW1A
F-box/WD repeat-containing protein 1A

1

16

Small-scale

0.479

High

1131316

FBW1B
F-box/WD repeat-containing protein 11

1

16

Small-scale

0.479

High

1143792

TGFR2
TGF-beta receptor type-2

1

20

High-throughput

0.479

High

1143952

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.479

High

1144419

EGLN
Endoglin

1

1

High-throughput

0.479

High

1144675

INADL
InaD-like protein

1

20

Small-scale

0.479

High

1160380

Q6P7T9
Nuclear factor of activated T-cells c1 isoform IA-IXS

1

4

Small-scale

0.479

High

1207482

LATS1
Serine/threonine-protein kinase LATS1

1

20

Small-scale

0.479

High

1257594

AMOT
Angiomotin

1

20

Small-scale

0.479

High

1322235

PALS1
Protein PALS1

1

19

Small-scale

0.479

High

1322236

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

2

Small-scale

0.479

High

1322237

CUL1
Cullin-1

1

5

Small-scale

0.479

High

1143646

TTF1
Transcription termination factor 1

1

0

Small-scale

0.458

High

1113240

Q3USK5
TEA domain family member 1

1

19

High-throughput

0.457

High

292497

LIN7C
Protein lin-7 homolog C

1

20

Small-scale

0.437

High


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Last updated: 15 Jul 2024