Protein: PSN1
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]

Gene: PSN1, Psen1
Organism: Mus musculus
Interactions: 30
UniProt ID: P49769

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000776 - kinetochore
GO:0001568 - blood vessel development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834394

PEN2
Gamma-secretase subunit PEN-2

4

7

Small-scale

0.867

High

834392

APH1A
Gamma-secretase subunit APH-1A

2

10

Small-scale

0.776

High

834380

PSN1
Presenilin-1

2

7

Small-scale

0.767

High

834385

CTNB1
Catenin beta-1

3

2

Small-scale

0.640

High

723552

NMDZ1
Glutamate receptor ionotropic, NMDA 1

3

1

Small-scale

0.633

High

834382

NICA
Nicastrin

3

6

Small-scale

0.624

High

834389

PSN2
Presenilin-2

1

7

Small-scale

0.618

High

834393

APH1B
Gamma-secretase subunit APH-1B

1

10

Small-scale

0.618

High

834397

GSK3B
Glycogen synthase kinase-3 beta

2

1

Small-scale

0.595

High

834388

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

Small-scale

0.515

High

802294

SYT1
Synaptotagmin-1

1

1

Small-scale

0.500

High

834398

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

Small-scale

0.493

High

834396

ARC
Activity-regulated cytoskeleton-associated protein

1

0

Small-scale

0.479

High

192826

NOTC2
Neurogenic locus notch homolog protein 2

1

10

Small-scale

0.479

High

454949

CADH1
Cadherin-1

1

5

Small-scale

0.479

High

544700

CADH2
Cadherin-2

1

6

Small-scale

0.479

High

643069

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

Small-scale

0.479

High

681668

NOTC4
Neurogenic locus notch homolog protein 4

1

11

Small-scale

0.479

High

723520

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

1

Small-scale

0.479

High

834384

NOTC1
Neurogenic locus notch homolog protein 1

1

11

Small-scale

0.479

High

834390

DLL1
Delta-like protein 1

1

11

Small-scale

0.479

High

834391

NOTC3
Neurogenic locus notch homolog protein 3

1

11

Small-scale

0.479

High

834395

TMED2
Transmembrane emp24 domain-containing protein 2

1

1

Small-scale

0.479

High

536147

CALR
Calreticulin

1

0

Small-scale

0.458

High

834381

EFNB1
Ephrin-B1

1

0

Small-scale

0.458

High

834383

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

0

Small-scale

0.458

High

834386

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

834399

PLD1
Phospholipase D1

1

0

Small-scale

0.458

High

834387

GSAP
Gamma-secretase-activating protein

1

1

Small-scale

0.457

High


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Last updated: 15 Jul 2024