Protein: LCK
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK)

Gene: LCK
Organism: Mus musculus
Interactions: 26
UniProt ID: P06240

Gene Ontology (top 5):
GO:0000242 - pericentriolar material
GO:0001772 - immunological synapse
GO:0003823 - antigen binding
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

411921

HCLS1
Hematopoietic lineage cell-specific protein

2

20

Small-scale

0.806

High

411920

ZAP70
Tyrosine-protein kinase ZAP-70

2

19

Small-scale

0.776

High

411913

PTPRC
Receptor-type tyrosine-protein phosphatase C

2

20

Small-scale

0.755

High

411932

SOCS6
Suppressor of cytokine signaling 6

1

19

Small-scale

0.740

High

411918

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.724

High

411912

CD4
T-cell surface glycoprotein CD4

4

1

Small-scale

0.670

High

411917

CBL
E3 ubiquitin-protein ligase CBL

3

20

Small-scale

0.640

High

411933

STAP1
Signal-transducing adaptor protein 1

1

4

Small-scale

0.621

High

193088

FYB1
FYN-binding protein 1

1

17

Small-scale

0.618

High

411925

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

10

High-throughput

0.618

High

411926

SKAP2
Src kinase-associated phosphoprotein 2

1

20

Small-scale

0.618

High

411930

DLG1
Disks large homolog 1

1

14

Small-scale

0.618

High

411931

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

8

Small-scale

0.618

High

411935

STK11
Serine/threonine-protein kinase STK11

1

11

Small-scale

0.618

High

411934

SH22A
SH2 domain-containing protein 2A

1

19

Small-scale

0.584

High

411915

KPCE
Protein kinase C epsilon type

1

18

Small-scale

0.575

High

411919

CSF3R
Granulocyte colony-stimulating factor receptor

1

13

Small-scale

0.553

High

353316

CD8A
T-cell surface glycoprotein CD8 alpha chain

2

0

Small-scale

0.551

High

411928

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.515

High

411924

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

Small-scale

0.501

High

411922

CD38
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

1

1

Small-scale

0.479

High

411923

WASP
Actin nucleation-promoting factor WAS

1

20

Small-scale

0.479

High

411929

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

411914

CD44
CD44 antigen

1

6

Small-scale

0.445

High

411916

TNR9
Tumor necrosis factor receptor superfamily member 9

1

10

Small-scale

0.437

High

411927

PTCA
Protein tyrosine phosphatase receptor type C-associated protein

1

1

Small-scale

0.407

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024