Protein: LCP2
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)

Gene: LCP2
Organism: Mus musculus
Interactions: 31
UniProt ID: Q60787

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005911 - cell-cell junction
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0035556 - intracellular signal transduction
GO:0036398 - TCR signalosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

292686

GRAP2
GRB2-related adaptor protein 2

2

20

Small-scale

0.767

High

1141127

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.755

High

665987

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

3

Small-scale

0.724

High

193099

FYB1
FYN-binding protein 1

2

12

Small-scale

0.712

High

976831

ITK
Tyrosine-protein kinase ITK/TSK

1

20

Small-scale

0.647

High

222842

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.618

High

1141384

NCK1
SH2/SH3 adapter protein Nck1

1

20

Small-scale

0.618

High

654983

VAV
Proto-oncogene vav

1

18

High-throughput

0.575

High

763395

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.575

High

1113013

SKAP2
Src kinase-associated phosphoprotein 2

1

16

High-throughput

0.575

High

1113318

SKAP1
Src kinase-associated phosphoprotein 1

1

12

High-throughput

0.575

High

1141377

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

High-throughput

0.575

High

222776

LAT
Linker for activation of T-cells family member 1

2

1

Small-scale

0.571

High

936329

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

2

10

Small-scale

0.571

High

1141386

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

0

High-throughput

0.546

High

1141385

GRAP
GRB2-related adapter protein

1

20

High-throughput

0.514

High

1141376

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

936467

WASP
Actin nucleation-promoting factor WAS

1

6

Small-scale

0.479

High

905340

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

High-throughput

0.445

High

910251

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.445

High

926796

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.445

High

933124

1433T
14-3-3 protein theta

1

20

High-throughput

0.445

High

1112054

CBLB
E3 ubiquitin-protein ligase CBL-B

1

9

High-throughput

0.445

High

1113694

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

20

High-throughput

0.445

High

1141383

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

12

Small-scale

0.445

High

1141379

THMS1
Protein THEMIS

1

0

High-throughput

0.426

High

1113142

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

6

High-throughput

0.407

High

1141381

WIPF1
WAS/WASL-interacting protein family member 1

1

9

High-throughput

0.407

High

1141382

SF3B4
Splicing factor 3B subunit 4

1

3

High-throughput

0.407

High

1141378

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.232

Low

1141380

SIT1
Signaling threshold-regulating transmembrane adapter 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024