Protein: CASP8
Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]

Gene: CASP8
Organism: Mus musculus
Interactions: 15
UniProt ID: O89110

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001817 - regulation of cytokine production
GO:0001841 - neural tube formation
GO:0004175 - endopeptidase activity
GO:0004197 - cysteine-type endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

292700

FADD
FAS-associated death domain protein

10

17

Small-scale

0.970

High

292695

TNR6
Tumor necrosis factor receptor superfamily member 6

4

16

Small-scale

0.683

High

193419

CFLAR
CASP8 and FADD-like apoptosis regulator

1

18

Small-scale

0.618

High

291433

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

6

Small-scale

0.618

High

292699

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

3

9

Small-scale

0.617

High

292693

IL1B
Interleukin-1 beta

2

7

Small-scale

0.595

High

292703

ATG5
Autophagy protein 5

2

0

Small-scale

0.585

High

292701

SQSTM
Sequestosome-1

2

4

Small-scale

0.584

High

292702

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.501

High

292704

TP8L2
Tumor necrosis factor alpha-induced protein 8-like protein 2

1

0

Small-scale

0.493

High

292694

ANDR
Androgen receptor

1

4

Small-scale

0.479

High

292696

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

292697

TANK
TRAF family member-associated NF-kappa-B activator

1

1

Small-scale

0.479

High

292698

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

1

Small-scale

0.479

High

292705

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

16

Small-scale

0.479

High


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Last updated: 15 Jul 2024