Protein: KNG1
Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor]

Gene: KNG1
Organism: Homo sapiens
Interactions: 50
UniProt ID: P01042

Gene Ontology (top 5):
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005102 - signaling receptor binding
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

245772

CATL2
Cathepsin L2

3

13

High-throughput

0.861

High

345179

CATO
Cathepsin O

3

15

High-throughput

0.861

High

345163

KLKB1
Plasma kallikrein

5

3

Small-scale

0.712

High

345171

CATL1
Procathepsin L

1

13

High-throughput

0.691

High

345173

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

13

High-throughput

0.691

High

345170

CAN1
Calpain-1 catalytic subunit

3

2

High-throughput

0.667

High

345187

TECT1
Tectonic-1

3

1

High-throughput

0.667

High

345186

MEP1A
Meprin A subunit alpha

1

3

Small-scale

0.647

High

345177

VHL
von Hippel-Lindau disease tumor suppressor

3

0

High-throughput

0.638

High

345188

TBB8
Tubulin beta-8 chain

2

7

High-throughput

0.611

High

345192

P3H3
Prolyl 3-hydroxylase 3

3

5

High-throughput

0.609

High

345194

GDPD1
Lysophospholipase D GDPD1

3

1

High-throughput

0.609

High

345199

ACE2
Angiotensin-converting enzyme 2

2

1

Small-scale

0.602

High

345197

SNX27
Sorting nexin-27

2

3

High-throughput

0.574

High

345185

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.537

High

198334

KLK10
Kallikrein-10

1

5

High-throughput

0.536

High

345176

CCR1
C-C chemokine receptor type 1

1

5

High-throughput

0.536

High

345181

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

341331

PLMN
Plasminogen

1

1

Small-scale

0.501

High

345161

FRIL
Ferritin light chain

1

3

Small-scale

0.501

High

345162

FA11
Coagulation factor XI

1

2

Small-scale

0.501

High

345168

ITB2
Integrin beta-2

1

3

Small-scale

0.501

High

345169

KLK1
Kallikrein-1

1

6

Small-scale

0.501

High

345172

ELNE
Neutrophil elastase

1

5

Small-scale

0.501

High

345178

ECE1
Endothelin-converting enzyme 1

1

3

Small-scale

0.501

High

345184

UPAR
Urokinase plasminogen activator surface receptor

1

2

Small-scale

0.501

High

345193

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

2

Small-scale

0.501

High

345201

C1QR1
Complement component C1q receptor

1

10

Small-scale

0.501

High

345189

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

High-throughput

0.489

High

345195

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.489

High

345198

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

2

High-throughput

0.489

High

345202

MRC2
C-type mannose receptor 2

1

5

High-throughput

0.489

High

345203

PHF11
PHD finger protein 11

1

6

High-throughput

0.489

High

345205

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

1

High-throughput

0.489

High

345164

VTNC
Vitronectin

1

0

Small-scale

0.480

High

345165

K2C1
Keratin, type II cytoskeletal 1

1

0

Small-scale

0.480

High

345166

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

2

High-throughput

0.479

High

345167

CPNS1
Calpain small subunit 1

1

1

High-throughput

0.479

High

345175

BKRB2
B2 bradykinin receptor

1

4

Small-scale

0.479

High

345180

BKRB1
B1 bradykinin receptor

1

4

Small-scale

0.479

High

345183

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.458

High

345174

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

260428

PITX3
Pituitary homeobox 3

1

2

Small-scale

0.437

High

345196

SC65
Endoplasmic reticulum protein SC65

1

5

High-throughput

0.437

High

345190

ZN562
Zinc finger protein 562

3

0

High-throughput

0.347

High

345200

APC1
Anaphase-promoting complex subunit 1

3

0

High-throughput

0.347

High

345204

APC5
Anaphase-promoting complex subunit 5

3

0

High-throughput

0.347

High

345182

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.279

Low

345191

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.279

Low

345160

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024