Protein: PLCE1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Pancreas-enriched phospholipase C) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)

Gene: PLCE1
Organism: Homo sapiens
Interactions: 16
UniProt ID: Q9P212

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004435 - phosphatidylinositol phospholipase C activity
GO:0004629 - phospholipase C activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

348976

RASN
GTPase NRas

1

20

High-throughput

0.698

High

349695

RASH
GTPase HRas

1

19

Small-scale

0.665

High

919682

RAP1A
Ras-related protein Rap-1A

1

19

Small-scale

0.618

High

199153

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

2

Small-scale

0.561

High

816290

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

1

High-throughput

0.541

High

432315

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.513

High

822185

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.513

High

1035029

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.513

High

1083025

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.513

High

387641

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

499290

KIT
Mast/stem cell growth factor receptor Kit

1

18

Small-scale

0.479

High

1216726

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

Small-scale

0.479

High

727072

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

963006

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

426748

H10
Histone H1.0

1

0

High-throughput

0.269

Low

1204421

PPR3B
Protein phosphatase 1 regulatory subunit 3B

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024