Protein: PI2R
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)

Gene: PI2R, PTGIR
Organism: Homo sapiens
Interactions: 71
UniProt ID: P43119

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

793179

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

4

20

Small-scale

0.878

High

600870

TA2R
Thromboxane A2 receptor

3

18

Small-scale

0.840

High

793220

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

2

0

High-throughput

0.770

High

793172

PI2R
Prostacyclin receptor

2

17

Small-scale

0.768

High

566320

KPCA
Protein kinase C alpha type

1

4

Small-scale

0.647

High

299150

CSCL1
CSC1-like protein 1

2

1

High-throughput

0.628

High

313923

PIGN
GPI ethanolamine phosphate transferase 1

2

2

High-throughput

0.628

High

392656

B3A2
Anion exchange protein 2

2

3

High-throughput

0.628

High

586011

SL9A1
Sodium/hydrogen exchanger 1

2

2

High-throughput

0.628

High

622770

COT2
COUP transcription factor 2

2

2

High-throughput

0.628

High

686160

GLPK
Glycerol kinase

2

1

High-throughput

0.628

High

734400

CXG1
Gap junction gamma-1 protein

2

9

High-throughput

0.628

High

793176

S12A2
Solute carrier family 12 member 2

2

6

High-throughput

0.628

High

793180

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

12

High-throughput

0.628

High

793181

PKD2
Polycystin-2

2

1

High-throughput

0.628

High

793182

FZD2
Frizzled-2

2

1

High-throughput

0.628

High

793186

CSCL2
CSC1-like protein 2

2

1

High-throughput

0.628

High

793188

LRC8E
Volume-regulated anion channel subunit LRRC8E

2

7

High-throughput

0.628

High

793190

ANO5
Anoctamin-5

2

2

High-throughput

0.628

High

793197

AT11C
Phospholipid-transporting ATPase IG

2

2

High-throughput

0.628

High

793200

EDA
Ectodysplasin-A

2

2

High-throughput

0.628

High

793207

S29A1
Equilibrative nucleoside transporter 1

2

1

High-throughput

0.628

High

793211

S12A9
Solute carrier family 12 member 9

2

8

High-throughput

0.628

High

793213

TTYH3
Protein tweety homolog 3

2

2

High-throughput

0.628

High

793216

PCD10
Protocadherin-10

2

2

High-throughput

0.628

High

793217

S53A1
Solute carrier family 53 member 1

2

1

High-throughput

0.628

High

793221

S12A6
Solute carrier family 12 member 6

2

8

High-throughput

0.628

High

793224

S12A7
Solute carrier family 12 member 7

2

8

High-throughput

0.628

High

793225

ZNT1
Proton-coupled zinc antiporter SLC30A1

2

3

High-throughput

0.628

High

793178

RB11A
Ras-related protein Rab-11A

2

1

Small-scale

0.619

High

793174

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

Small-scale

0.618

High

793218

GHRL
Appetite-regulating hormone

1

2

Small-scale

0.618

High

793173

SC6A8
Sodium- and chloride-dependent creatine transporter 1

2

0

High-throughput

0.602

High

793191

DPH6
Diphthine--ammonia ligase

2

0

High-throughput

0.602

High

793193

T179B
Transmembrane protein 179B

2

0

High-throughput

0.602

High

793196

S15A4
Solute carrier family 15 member 4

2

0

High-throughput

0.602

High

793214

XKR8
XK-related protein 8

2

0

High-throughput

0.602

High

373104

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

2

2

High-throughput

0.574

High

793177

MFAP3
Microfibril-associated glycoprotein 3

2

1

High-throughput

0.574

High

793184

MTX3
Metaxin-3

2

3

High-throughput

0.574

High

793189

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

2

High-throughput

0.574

High

793195

DAAF5
Dynein axonemal assembly factor 5

2

2

High-throughput

0.574

High

793198

MFSD8
Major facilitator superfamily domain-containing protein 8

2

3

High-throughput

0.574

High

793201

GLMN
Glomulin

2

2

High-throughput

0.574

High

793215

DJC18
DnaJ homolog subfamily C member 18

2

2

High-throughput

0.574

High

793185

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

20

Small-scale

0.552

High

793194

NHRF4
Na(+)/H(+) exchange regulatory cofactor NHE-RF4

1

20

Small-scale

0.552

High

503615

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.536

High

526492

GP1BB
Platelet glycoprotein Ib beta chain

1

3

High-throughput

0.536

High

793175

CTR2
Cationic amino acid transporter 2

1

4

High-throughput

0.536

High

793205

VMP1
Vacuole membrane protein 1

1

1

High-throughput

0.536

High

793208

GCP2
Gamma-tubulin complex component 2

1

7

High-throughput

0.536

High

793209

YIPF4
Protein YIPF4

1

4

High-throughput

0.536

High

793212

OSBL8
Oxysterol-binding protein-related protein 8

1

2

High-throughput

0.536

High

793222

SNX14
Sorting nexin-14

1

1

High-throughput

0.536

High

793223

FLVC1
Heme transporter FLVCR1

1

1

High-throughput

0.536

High

217711

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

0

Small-scale

0.529

High

200022

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

1

0

High-throughput

0.513

High

793187

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.513

High

793202

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

793204

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.513

High

793203

S2546
Mitochondrial outer membrane protein SLC25A46

1

3

High-throughput

0.489

High

793206

ARL5B
ADP-ribosylation factor-like protein 5B

1

5

High-throughput

0.489

High

793210

NFIP1
NEDD4 family-interacting protein 1

1

4

High-throughput

0.489

High

592142

RAB5A
Ras-related protein Rab-5A

1

3

Small-scale

0.479

High

793199

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.439

High

654143

CALX
Calnexin

1

5

Small-scale

0.437

High

793183

CEGT
Ceramide glucosyltransferase

2

0

High-throughput

0.328

High

793192

ATG9A
Autophagy-related protein 9A

2

0

High-throughput

0.328

High

793219

FA8A1
Protein FAM8A1

2

0

High-throughput

0.328

High


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Last updated: 15 Jul 2024