Protein: IL37
Interleukin-37 (IL-37) (FIL1 zeta) (IL-1X) (Interleukin-1 family member 7) (IL-1F7) (Interleukin-1 homolog 4) (IL-1H) (IL-1H4) (Interleukin-1 zeta) (IL-1 zeta) (Interleukin-1-related protein) (IL-1RP1)

Gene: IL37
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q9NZH6

Gene Ontology (top 5):
GO:0002437 - inflammatory response to antigenic stimulus
GO:0005125 - cytokine activity
GO:0005149 - interleukin-1 receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1026657

FADD
FAS-associated death domain protein

3

3

High-throughput

0.667

High

609581

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.630

High

365242

FRIH
Ferritin heavy chain

2

1

High-throughput

0.628

High

1349110

IL37
Interleukin-37

1

0

Small-scale

0.614

High

1035370

IL18R
Interleukin-18 receptor 1

2

9

Small-scale

0.608

High

1218222

CC103
Coiled-coil domain-containing protein 103

2

0

High-throughput

0.602

High

212533

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

667495

CASP1
Caspase-1

1

6

Small-scale

0.569

High

830300

CASP4
Caspase-4

1

6

Small-scale

0.569

High

1349111

IRPL1
Interleukin-1 receptor accessory protein-like 1

1

9

Small-scale

0.553

High

624521

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

676772

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.513

High

1166261

AMTN
Amelotin

1

0

High-throughput

0.513

High

1229937

D106A
Beta-defensin 106

1

0

High-throughput

0.513

High

1292943

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.513

High

1349113

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

414086

GELS
Gelsolin

1

0

High-throughput

0.493

High

657987

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

1349112

UBQL1
Ubiquilin-1

1

0

High-throughput

0.493

High

275123

RENR
Renin receptor

1

2

High-throughput

0.489

High

1201380

MOGT3
2-acylglycerol O-acyltransferase 3

1

1

High-throughput

0.489

High

950308

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.479

High

1291960

P2Y11
P2Y purinoceptor 11

1

4

High-throughput

0.470

High

330222

I18BP
Interleukin-18-binding protein

1

0

Small-scale

0.458

High

1282059

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.439

High

1317528

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.439

High

1101413

GSG1
Germ cell-specific gene 1 protein

3

0

High-throughput

0.345

High

327118

GPAN1
G patch domain and ankyrin repeat-containing protein 1

1

0

High-throughput

0.279

Low

1125943

BEX5
Protein BEX5

1

0

High-throughput

0.279

Low

1136922

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.279

Low

1336461

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1343432

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.279

Low

1149581

SL9A4
Sodium/hydrogen exchanger 4

1

0

High-throughput

0.269

Low

1060501

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1349114

Q9Y649
GW128

1

0

High-throughput

0.268

Low

200848

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024