Protein: GSHR
Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)

Gene: GSHR, GSR
Organism: Homo sapiens
Interactions: 50
UniProt ID: P00390

Gene Ontology (top 5):
GO:0004362 - glutathione-disulfide reductase (NADPH) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
GO:0006749 - glutathione metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335604

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.501

High

226192

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

298026

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

335590

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

335591

ISG15
Ubiquitin-like protein ISG15

1

7

High-throughput

0.479

High

335594

ENOA
Alpha-enolase

1

3

High-throughput

0.479

High

335595

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

335601

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

335603

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

335605

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

335608

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.479

High

335609

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.479

High

335610

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

335612

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

335617

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

335622

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

335623

OPTN
Optineurin

1

2

High-throughput

0.479

High

335629

DNJB9
DnaJ homolog subfamily B member 9

1

3

High-throughput

0.479

High

241927

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

255408

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

259995

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.458

High

335588

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

335593

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.458

High

335597

CD9
CD9 antigen

1

0

High-throughput

0.458

High

335606

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

335619

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

335620

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

335599

GRN
Progranulin

1

1

High-throughput

0.445

High

335589

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

335596

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

335598

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

335600

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

335602

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.437

High

335615

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

335616

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.437

High

335618

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

335625

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

335626

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

335630

DJB11
DnaJ homolog subfamily B member 11

1

2

High-throughput

0.437

High

335592

JUN
Transcription factor Jun

1

4

High-throughput

0.407

High

335621

PJA1
E3 ubiquitin-protein ligase Praja-1

1

0

High-throughput

0.282

High

335627

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.282

High

335624

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

204892

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

335611

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

335613

DUS29
Dual specificity phosphatase 29

1

0

High-throughput

0.249

Low

335614

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

335628

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

335631

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

335607

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024