Protein: HEXA
Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha)

Gene: HEXA
Organism: Homo sapiens
Interactions: 31
UniProt ID: P06865

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0004563 - beta-N-acetylhexosaminidase activity
GO:0005764 - lysosome
GO:0005829 - cytosol
GO:0005975 - carbohydrate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420705

HEXB
Beta-hexosaminidase subunit beta

3

1

Small-scale

0.866

High

420724

DHRS4
Dehydrogenase/reductase SDR family member 4

2

0

High-throughput

0.602

High

420706

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.536

High

420711

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.536

High

420721

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

1

High-throughput

0.536

High

235668

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

420707

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

420712

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

420714

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.513

High

420729

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.513

High

420723

SH23A
SH2 domain-containing protein 3A

1

4

High-throughput

0.489

High

337310

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.479

High

411942

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.479

High

420710

CRK
Adapter molecule crk

1

1

High-throughput

0.479

High

420713

CUL3
Cullin-3

1

1

High-throughput

0.479

High

420725

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

420726

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

420719

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

226273

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

420715

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

420718

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

420720

OPTN
Optineurin

1

0

High-throughput

0.458

High

204932

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

420717

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

420708

SAP3
Ganglioside GM2 activator

1

0

Small-scale

0.426

High

420716

TERF2
Telomeric repeat-binding factor 2

2

0

High-throughput

0.328

High

420728

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.282

High

420727

PA2GD
Group IID secretory phospholipase A2

1

0

High-throughput

0.279

Low

420709

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

420730

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

420722

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024