Protein: BLNK
B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65)

Gene: BLNK
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q8WV28

Gene Ontology (top 5):
GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924727

GRB2
Growth factor receptor-bound protein 2

7

20

Small-scale

0.964

High

986387

BTK
Tyrosine-protein kinase BTK

6

20

Small-scale

0.937

High

796616

KSYK
Tyrosine-protein kinase SYK

3

20

Small-scale

0.827

High

383899

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

275217

GRAP2
GRB2-related adapter protein 2

2

20

Small-scale

0.768

High

1261033

CD2AP
CD2-associated protein

1

20

Small-scale

0.715

High

499277

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

562659

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

6

Small-scale

0.691

High

1261029

SH3K1
SH3 domain-containing kinase-binding protein 1

3

20

Small-scale

0.677

High

338753

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

601960

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

516095

CD79A
B-cell antigen receptor complex-associated protein alpha chain

3

0

Small-scale

0.639

High

209129

NCK2
Cytoplasmic protein NCK2

1

20

Small-scale

0.618

High

254923

CPNE3
Copine-3

1

1

High-throughput

0.618

High

433917

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.618

High

548737

VAV
Proto-oncogene vav

1

20

Small-scale

0.618

High

557750

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.618

High

581031

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

8

Small-scale

0.618

High

665929

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

10

Small-scale

0.618

High

802878

CRKL
Crk-like protein

1

20

Small-scale

0.618

High

1060199

MYPC3
Myosin-binding protein C, cardiac-type

1

16

Small-scale

0.618

High

1261030

VAV3
Guanine nucleotide exchange factor VAV3

1

20

Small-scale

0.618

High

610462

CBL
E3 ubiquitin-protein ligase CBL

1

13

Small-scale

0.561

High

1261028

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

10

Small-scale

0.561

High

487615

ANDR
Androgen receptor

1

18

High-throughput

0.536

High

1035393

GAB1
GRB2-associated-binding protein 1

1

17

High-throughput

0.536

High

800992

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

8

Small-scale

0.536

High

1184731

DOK3
Docking protein 3

1

18

Small-scale

0.536

High

981660

REL
Proto-oncogene c-Rel

1

4

Small-scale

0.515

High

601793

CD72
B-cell differentiation antigen CD72

1

2

Small-scale

0.479

High

714324

HSP74
Heat shock 70 kDa protein 4

1

7

Small-scale

0.479

High

813110

CAZA2
F-actin-capping protein subunit alpha-2

1

1

Small-scale

0.479

High

813630

CAPZB
F-actin-capping protein subunit beta

1

1

Small-scale

0.479

High

842587

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.479

High

857178

CAZA1
F-actin-capping protein subunit alpha-1

1

1

Small-scale

0.479

High

1122376

WDR81
WD repeat-containing protein 81

1

4

Small-scale

0.479

High

1261027

HS105
Heat shock protein 105 kDa

1

8

Small-scale

0.479

High

1261031

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

1

Small-scale

0.479

High

1261032

TLN1
Talin-1

1

7

Small-scale

0.479

High

325290

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

Small-scale

0.458

High

1165232

SCIMP
SLP adapter and CSK-interacting membrane protein

1

1

Small-scale

0.445

High

1170207

CL17A
C-type lectin domain family 17, member A

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024