Protein: NOTC1
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]

Gene: NOTC1, Notch1
Organism: Mus musculus
Interactions: 22
UniProt ID: Q01705

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001554 - luteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678826

SUH
Recombining binding protein suppressor of hairless

6

9

Small-scale

0.942

High

966330

ITCH
E3 ubiquitin-protein ligase Itchy

2

15

Small-scale

0.653

High

966325

DLL1
Delta-like protein 1

1

18

Small-scale

0.647

High

378815

GRAB
Granzyme B(G,H)

1

9

Small-scale

0.618

High

966328

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

13

Small-scale

0.618

High

966335

EGFL7
Epidermal growth factor-like protein 7

1

19

Small-scale

0.618

High

966327

MAML1
Mastermind-like protein 1

1

17

Small-scale

0.575

High

966326

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

0

Small-scale

0.513

High

966334

WDR12
Ribosome biogenesis protein WDR12

1

16

Small-scale

0.501

High

966322

SMCA4
Transcription activator BRG1

1

6

Small-scale

0.500

High

966332

KAT2B
Histone acetyltransferase KAT2B

1

7

Small-scale

0.481

High

966333

KAT2A
Histone acetyltransferase KAT2A

1

9

Small-scale

0.481

High

222434

EOMES
Eomesodermin homolog

1

2

Small-scale

0.479

High

420396

TNFA
Tumor necrosis factor

1

1

Small-scale

0.479

High

834384

PSN1
Presenilin-1

1

11

Small-scale

0.479

High

966323

XIAP
E3 ubiquitin-protein ligase XIAP

1

15

Small-scale

0.479

High

966324

PSN2
Presenilin-2

1

11

Small-scale

0.479

High

966329

SENP7
Sentrin-specific protease 7

1

3

Small-scale

0.479

High

966336

NUMB
Protein numb homolog

1

8

Small-scale

0.479

High

500291

PERF
Perforin-1

1

0

Small-scale

0.458

High

667789

NOS2
Nitric oxide synthase, inducible

1

0

Small-scale

0.458

High

966331

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

2

Small-scale

0.457

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024