Protein: KSYK
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase)

Gene: KSYK, Syk
Organism: Mus musculus
Interactions: 39
UniProt ID: P48025

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001775 - cell activation
GO:0001784 - phosphotyrosine residue binding
GO:0001819 - positive regulation of cytokine production
GO:0001820 - serotonin secretion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

786511

STAT3
Signal transducer and activator of transcription 3

1

20

Small-scale

0.771

High

815728

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.724

High

815735

CLC7A
C-type lectin domain family 7 member A

5

15

Small-scale

0.702

High

815724

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.647

High

403423

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.618

High

639437

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.618

High

665979

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

Small-scale

0.618

High

815727

DOK1
Docking protein 1

1

20

Small-scale

0.618

High

815733

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

19

Small-scale

0.618

High

815739

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

20

Small-scale

0.618

High

815745

TLR4
Toll-like receptor 4

1

20

Small-scale

0.618

High

815746

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.618

High

815730

Q5U3L0
SH3-domain binding protein 2

1

11

Small-scale

0.579

High

536207

FGR
Tyrosine-protein kinase Fgr

1

19

Small-scale

0.575

High

722897

CD22
B-cell receptor CD22

1

20

Small-scale

0.561

High

815725

TBA4A
Tubulin alpha-4A chain

1

20

Small-scale

0.561

High

815734

OBF1
POU domain class 2-associating factor 1

1

0

Small-scale

0.537

High

607536

MYD88
Myeloid differentiation primary response protein MyD88

1

20

Small-scale

0.536

High

815736

TCAM1
TIR domain-containing adapter molecule 1

1

18

Small-scale

0.536

High

222510

ITB3
Integrin beta-3

1

20

Small-scale

0.479

High

594160

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

7

Small-scale

0.479

High

610566

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

626854

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

20

Small-scale

0.479

High

667119

CASP1
Caspase-1

1

7

Small-scale

0.479

High

815726

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

815729

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

Small-scale

0.479

High

815731

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

815737

FACD2
Fanconi anemia group D2 protein homolog

1

11

High-throughput

0.479

High

815738

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.479

High

815741

TRI31
E3 ubiquitin-protein ligase TRIM31

1

16

Small-scale

0.479

High

815743

NFAM1
NFAT activation molecule 1

1

1

Small-scale

0.479

High

815747

CLC4D
C-type lectin domain family 4 member D

1

12

Small-scale

0.479

High

815732

I15RA
Interleukin-15 receptor subunit alpha

1

0

Small-scale

0.458

High

392639

B3AT
Band 3 anion transport protein

1

8

Small-scale

0.457

High

421448

CSF1
Macrophage colony-stimulating factor 1

1

15

Small-scale

0.445

High

815742

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

5

Small-scale

0.445

High

815744

ASC
Apoptosis-associated speck-like protein containing a CARD

1

6

Small-scale

0.445

High

815740

WIPF1
WAS/WASL-interacting protein family member 1

1

20

Small-scale

0.437

High


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Last updated: 15 Jul 2024