Protein: PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)

Gene: PLCG1
Organism: Mus musculus
Interactions: 27
UniProt ID: Q62077

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001726 - ruffle
GO:0004435 - phosphatidylinositol phospholipase C activity
GO:0004629 - phospholipase C activity
GO:0005085 - guanyl-nucleotide exchange factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

404014

PGFRB
Platelet-derived growth factor receptor beta

2

20

Small-scale

0.768

High

1141132

GRB2
Growth factor receptor-bound protein 2

2

19

Small-scale

0.737

High

1143293

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

5

Small-scale

0.724

High

546302

NTRK2
BDNF/NT-3 growth factors receptor

1

20

Small-scale

0.691

High

540269

EPOR
Erythropoietin receptor

1

7

Small-scale

0.690

High

729715

VGFR1
Vascular endothelial growth factor receptor 1

1

19

Small-scale

0.665

High

729415

VGFR2
Vascular endothelial growth factor receptor 2

1

18

Small-scale

0.625

High

222780

LAT
Linker for activation of T-cells family member 1

3

2

Small-scale

0.624

High

530207

NCAM1
Neural cell adhesion molecule 1

1

3

Small-scale

0.618

High

623690

TEC
Tyrosine-protein kinase Tec

1

18

Small-scale

0.618

High

1112476

NTRK1
High affinity nerve growth factor receptor

1

20

Small-scale

0.618

High

1143290

SOS1
Son of sevenless homolog 1

1

6

Small-scale

0.618

High

1143295

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

3

Small-scale

0.618

High

1143297

STK11
Serine/threonine-protein kinase STK11

1

1

Small-scale

0.618

High

1112196

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.613

High

1143296

GAB1
GRB2-associated-binding protein 1

1

4

Small-scale

0.590

High

1141377

LCP2
Lymphocyte cytosolic protein 2

1

4

High-throughput

0.575

High

610604

CBL
E3 ubiquitin-protein ligase CBL

2

3

Small-scale

0.571

High

722902

CD22
B-cell receptor CD22

1

6

Small-scale

0.561

High

723585

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

3

High-throughput

0.536

High

817304

LEPR
Leptin receptor

1

2

Small-scale

0.506

High

447094

ITB1
Integrin beta-1

1

2

High-throughput

0.501

High

956228

DAB1
Disabled homolog 1

1

3

Small-scale

0.479

High

963731

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

3

High-throughput

0.479

High

1143291

VILI
Villin-1

1

4

Small-scale

0.479

High

1143292

THMS1
Protein THEMIS

1

1

Small-scale

0.445

High

1143294

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.438

High


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Last updated: 15 Jul 2024