Protein: VDAC1
Mitochondrial outer membrane protein porin 1 (Voltage-dependent anion-selective channel protein 1) (VDAC-1)

Gene: VDAC1, POR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 232
UniProt ID: P04840

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006811 - monoatomic ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

389851

TOM40
Mitochondrial import receptor subunit TOM40

5

1

Small-scale

0.906

High

389951

TOM22
Mitochondrial import receptor subunit TOM22

5

1

Small-scale

0.906

High

389969

SAM50
Sorting assembly machinery 50 kDa subunit

4

2

Small-scale

0.692

High

389840

OM45
Mitochondrial outer membrane protein OM45

6

0

Small-scale

0.690

High

389836

SAM35
Sorting assembly machinery 35 kDa subunit

5

0

Small-scale

0.678

High

389844

ADT2
ADP,ATP carrier protein 2

3

8

Small-scale

0.656

High

389886

TOM20
Mitochondrial import receptor subunit TOM20

3

5

Small-scale

0.640

High

389829

HSP71
Heat shock protein SSA1

3

2

High-throughput

0.633

High

389837

HSC82
ATP-dependent molecular chaperone HSC82

3

6

High-throughput

0.633

High

389954

SAM37
Sorting assembly machinery 37 kDa subunit

1

0

Small-scale

0.614

High

389894

MIC60
MICOS complex subunit MIC60

3

0

Small-scale

0.613

High

389845

HSP60
Heat shock protein 60, mitochondrial

2

1

High-throughput

0.611

High

389921

IMB4
Importin subunit beta-4

2

1

Small-scale

0.601

High

389908

RPN1
26S proteasome regulatory subunit RPN1

2

0

High-throughput

0.585

High

389937

MMM1
Maintenance of mitochondrial morphology protein 1

2

0

Small-scale

0.585

High

389958

MDM34
Mitochondrial distribution and morphology protein 34

2

0

Small-scale

0.585

High

336025

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

2

1

High-throughput

0.584

High

365523

HSP82
ATP-dependent molecular chaperone HSP82

2

6

High-throughput

0.584

High

389814

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

2

6

High-throughput

0.584

High

389825

HSP77
Import motor subunit, mitochondrial

2

2

High-throughput

0.584

High

389936

PHB1
Prohibitin-1

2

10

Small-scale

0.584

High

389952

PHB2
Prohibitin-2

2

9

High-throughput

0.584

High

389850

MPCP
Mitochondrial phosphate carrier protein

2

9

High-throughput

0.571

High

389873

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

2

1

Small-scale

0.571

High

224229

MDM35
Mitochondrial distribution and morphology protein 35

2

0

Small-scale

0.559

High

389880

HSP78
Heat shock protein 78, mitochondrial

2

0

High-throughput

0.559

High

389902

OM14
Mitochondrial outer membrane protein OM14

2

0

Small-scale

0.559

High

389943

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

389807

SNF1
Carbon catabolite-derepressing protein kinase

1

4

Small-scale

0.552

High

389819

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.536

High

389823

TBA3
Tubulin alpha-3 chain

1

3

High-throughput

0.536

High

389852

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

3

High-throughput

0.536

High

389878

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

High-throughput

0.536

High

389884

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.536

High

389965

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.536

High

389973

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

389999

CDC53
Cell division control protein 53

1

1

High-throughput

0.536

High

390010

DUF1
DUB-associated factor 1

1

6

High-throughput

0.536

High

389979

RUVB1
RuvB-like protein 1

2

2

High-throughput

0.521

High

390006

RUVB2
RuvB-like protein 2

2

2

High-throughput

0.521

High

389906

NCB5R
NADH-cytochrome b5 reductase 1

1

4

High-throughput

0.515

High

389849

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.513

High

389860

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

389865

XPO1
Exportin-1

1

0

High-throughput

0.513

High

389911

LYS1
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

1

0

High-throughput

0.513

High

389934

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.513

High

389939

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

389955

INP52
Polyphosphatidylinositol phosphatase INP52

1

0

High-throughput

0.513

High

389963

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.513

High

389966

LTO1
Protein LTO1

1

0

High-throughput

0.513

High

390005

HSP42
Heat shock protein 42

1

0

High-throughput

0.513

High

389993

GAS4
1,3-beta-glucanosyltransferase GAS4

1

1

High-throughput

0.494

High

389903

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.493

High

389929

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.493

High

389948

BXI1
Bax inhibitor 1

1

0

Small-scale

0.493

High

389806

RHO2
GTP-binding protein RHO2

1

7

High-throughput

0.489

High

389846

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

3

High-throughput

0.489

High

389890

YPT53
GTP-binding protein YPT53

1

11

High-throughput

0.489

High

389897

TAF5
Transcription initiation factor TFIID subunit 5

1

8

High-throughput

0.489

High

389982

KU80
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.489

High

389986

UTP13
U3 small nucleolar RNA-associated protein 13

1

4

High-throughput

0.489

High

333293

CYC1
Cytochrome c isoform 1

1

2

High-throughput

0.479

High

335920

COX2
Cytochrome c oxidase subunit 2

1

1

High-throughput

0.479

High

336075

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.479

High

336106

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

1

High-throughput

0.479

High

342606

ENO1
Enolase 1

1

1

Small-scale

0.479

High

375186

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

389801

ATPF
ATP synthase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

389811

TOM70
Mitochondrial import receptor subunit TOM70

1

2

Small-scale

0.479

High

389812

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

389813

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

6

High-throughput

0.479

High

389821

ATPO
ATP synthase subunit 5, mitochondrial

1

3

High-throughput

0.479

High

389826

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

389843

ADT3
ADP,ATP carrier protein 3

1

8

High-throughput

0.479

High

389858

TAH1
TPR repeat-containing protein associated with Hsp90

1

5

Small-scale

0.479

High

389869

SP110
Spindle pole body component 110

1

4

High-throughput

0.479

High

389876

YPT7
Ypt/Rab-type GTPase YPT7

1

9

Small-scale

0.479

High

389893

TCD2
tRNA threonylcarbamoyladenosine dehydratase 2

1

1

High-throughput

0.479

High

389907

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

1

High-throughput

0.479

High

389912

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

389917

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.479

High

389920

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

2

Small-scale

0.479

High

389926

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

1

1

High-throughput

0.479

High

389928

TM108
Protein TMA108

1

2

High-throughput

0.479

High

389942

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.479

High

389957

VID30
Vacuolar import and degradation protein 30

1

2

High-throughput

0.479

High

389977

YP109
ABC1 family protein YPL109C, mitochondrial

1

2

Small-scale

0.479

High

389978

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.479

High

389981

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

389991

MCP2
ABC1 family protein MCP2

1

2

High-throughput

0.479

High

390000

FSF1
Sideroflexin FSF1

1

3

High-throughput

0.479

High

390007

SMC6
Structural maintenance of chromosomes protein 6

1

4

High-throughput

0.479

High

389835

ATC1
Calcium-transporting ATPase 1

1

2

High-throughput

0.470

High

389901

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

1

High-throughput

0.470

High

251761

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

1

0

Small-scale

0.458

High

333350

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.458

High

333403

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

0

High-throughput

0.458

High

345256

STF1
F(1)-ATPase inhibitor STF1, mitochondrial

1

0

High-throughput

0.458

High

373181

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

389802

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

389803

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

389804

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

389809

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

389817

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.458

High

389818

NUC1
Mitochondrial nuclease

1

0

Small-scale

0.458

High

389820

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

0

High-throughput

0.458

High

389828

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

389834

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

389847

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

389855

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

389861

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

Small-scale

0.458

High

389866

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

389868

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

389871

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

High-throughput

0.458

High

389872

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

0

High-throughput

0.458

High

389875

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

389877

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

389888

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

389895

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

389896

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

High-throughput

0.458

High

389904

MIC12
MICOS complex subunit MIC12

1

0

Small-scale

0.458

High

389909

MDM31
Mitochondrial distribution and morphology protein 31

1

0

Small-scale

0.458

High

389918

SS120
Protein SSP120

1

0

High-throughput

0.458

High

389919

OXA1
Mitochondrial inner membrane protein OXA1

1

0

High-throughput

0.458

High

389923

CCS1
Superoxide dismutase 1 copper chaperone

1

0

High-throughput

0.458

High

389924

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

0

High-throughput

0.458

High

389927

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.458

High

389932

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

389940

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

389944

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

389945

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

389946

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

Small-scale

0.458

High

389947

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

389949

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

389960

MCY1
Putative mitochondrial cysteine synthase

1

0

High-throughput

0.458

High

389961

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

389962

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.458

High

389964

RCF2
Respiratory supercomplex factor 2, mitochondrial

1

0

High-throughput

0.458

High

389967

IGO1
mRNA stability protein IGO1

1

0

Small-scale

0.458

High

389971

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

0

Small-scale

0.458

High

389972

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.458

High

389974

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

0

High-throughput

0.458

High

389975

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

389983

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

389990

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

389995

SGO1
Shugoshin

1

0

High-throughput

0.458

High

389996

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

0

Small-scale

0.458

High

389998

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

390004

TIM22
Mitochondrial import inner membrane translocase subunit TIM22

1

0

Small-scale

0.458

High

390008

MDM12
Mitochondrial distribution and morphology protein 12

1

0

Small-scale

0.458

High

390009

MIC10
MICOS complex subunit MIC10

1

0

Small-scale

0.458

High

360680

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

367584

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

389808

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.445

High

389810

FAS1
Fatty acid synthase subunit beta

1

1

High-throughput

0.445

High

389815

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

389822

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.445

High

389830

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

389833

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

389838

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

389870

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

389885

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.445

High

389899

IMB2
Importin subunit beta-2

1

1

High-throughput

0.445

High

389914

FHP
Flavohemoprotein

1

4

High-throughput

0.445

High

389922

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

390003

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.445

High

389816

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

389848

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.437

High

389853

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

389863

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

389864

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

389881

IXR1
Intrastrand cross-link recognition protein

1

2

Small-scale

0.437

High

389889

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

389933

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

333651

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

389800

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.426

High

389841

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.426

High

389930

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

389938

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

355288

H2B1
Histone H2B.1

1

2

High-throughput

0.407

High

389799

H2A2
Histone H2A.2

1

1

High-throughput

0.407

High

389832

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

1

High-throughput

0.407

High

389839

EF3A
Elongation factor 3A

1

2

High-throughput

0.407

High

389842

VATA
V-type proton ATPase catalytic subunit A

1

5

High-throughput

0.407

High

389867

EF2
Elongation factor 2

1

2

High-throughput

0.407

High

389925

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.407

High

389970

H3
Histone H3

1

1

High-throughput

0.407

High

389987

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

2

0

High-throughput

0.313

High

389831

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.279

Low

389854

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.279

Low

389856

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.279

Low

389879

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.279

Low

389935

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.279

Low

389956

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.279

Low

390002

GET3
ATPase GET3

1

0

High-throughput

0.279

Low

389883

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.269

Low

389915

ERP2
Protein ERP2

1

0

High-throughput

0.269

Low

389931

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.269

Low

389988

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

High-throughput

0.269

Low

357756

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

389805

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

389824

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

389827

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

389857

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

389859

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

389862

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

389882

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

389887

SFK1
Protein SFK1

1

0

Small-scale

0.249

Low

389891

EMC3
ER membrane protein complex subunit 3

1

0

Small-scale

0.249

Low

389892

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

389898

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

389900

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.249

Low

389905

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

389910

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

389913

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

389941

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

389950

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

389959

GUP1
Membrane-bound O-acyltransferase GUP1

1

0

Small-scale

0.249

Low

389980

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.249

Low

389989

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

389992

EXP1
ER export of PMA1 protein 1

1

0

High-throughput

0.249

Low

389994

ENB1
Siderophore iron transporter ENB1

1

0

High-throughput

0.249

Low

389997

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

356146

H4
Histone H4

1

0

High-throughput

0.232

Low

389874

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low

389916

NPR2
Nitrogen permease regulator 2

1

0

High-throughput

0.232

Low

389953

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.232

Low

389968

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.232

Low

389976

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.232

Low

389984

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.232

Low

389985

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.232

Low

390001

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024