Protein: RGS2
Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)

Gene: RGS2
Organism: Homo sapiens
Interactions: 78
UniProt ID: P41220

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0001975 - response to amphetamine
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782058

STK26
Serine/threonine-protein kinase 26

2

2

High-throughput

0.811

High

782042

WDR74
WD repeat-containing protein 74

2

4

High-throughput

0.801

High

282840

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

1

High-throughput

0.783

High

782032

KGP1
cGMP-dependent protein kinase 1

1

5

Small-scale

0.724

High

782039

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

Small-scale

0.724

High

782067

NINL
Ninein-like protein

3

4

High-throughput

0.678

High

226744

PRKN
E3 ubiquitin-protein ligase parkin

3

5

High-throughput

0.672

High

782038

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

7

High-throughput

0.654

High

397146

KPCG
Protein kinase C gamma type

1

5

Small-scale

0.647

High

408572

KPCB
Protein kinase C beta type

1

4

Small-scale

0.647

High

444680

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

20

Small-scale

0.647

High

566314

KPCA
Protein kinase C alpha type

1

4

Small-scale

0.647

High

675585

GNA15
Guanine nucleotide-binding protein subunit alpha-15

1

20

Small-scale

0.647

High

782018

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

Small-scale

0.647

High

782024

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

20

Small-scale

0.647

High

782029

PTN13
Tyrosine-protein phosphatase non-receptor type 13

2

1

High-throughput

0.628

High

782050

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

2

High-throughput

0.628

High

503594

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.620

High

782025

DYL1
Dynein light chain 1, cytoplasmic

2

1

High-throughput

0.620

High

782027

DDR1
Epithelial discoidin domain-containing receptor 1

2

3

High-throughput

0.620

High

782068

GIT1
ARF GTPase-activating protein GIT1

2

6

High-throughput

0.620

High

782019

MAP2
Methionine aminopeptidase 2

2

0

High-throughput

0.602

High

782040

STRP1
Striatin-interacting protein 1

2

0

High-throughput

0.602

High

782049

MIPO1
Mirror-image polydactyly gene 1 protein

2

0

High-throughput

0.602

High

782051

NIPS1
Protein NipSnap homolog 1

2

0

High-throughput

0.594

High

782057

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

2

0

High-throughput

0.594

High

782061

VPS29
Vacuolar protein sorting-associated protein 29

2

0

High-throughput

0.594

High

782043

STXB4
Syntaxin-binding protein 4

2

8

High-throughput

0.574

High

782037

DDB1
DNA damage-binding protein 1

2

0

Small-scale

0.559

High

782053

FBX44
F-box only protein 44

2

0

Small-scale

0.559

High

225956

KLK8
Kallikrein-8

1

1

High-throughput

0.541

High

782023

RAP1B
Ras-related protein Rap-1b

1

10

High-throughput

0.541

High

317551

ADCY5
Adenylate cyclase type 5

1

0

Small-scale

0.537

High

782066

NISCH
Nischarin

1

1

High-throughput

0.536

High

782064

NEB1
Neurabin-1

1

8

Small-scale

0.527

High

782056

GDE1
Glycerophosphodiester phosphodiesterase 1

1

1

Small-scale

0.527

High

451385

CLCA
Clathrin light chain A

1

0

High-throughput

0.518

High

782030

FZD5
Frizzled-5

1

0

High-throughput

0.518

High

782045

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.518

High

782020

H2BFS
Histone H2B type F-S

1

3

High-throughput

0.515

High

782059

IBTK
Inhibitor of Bruton tyrosine kinase

1

2

High-throughput

0.515

High

355212

MYG
Myoglobin

1

0

High-throughput

0.513

High

782041

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.513

High

782055

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.513

High

326038

TSN15
Tetraspanin-15

1

1

High-throughput

0.508

High

475447

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.508

High

485209

TZAP
Telomere zinc finger-associated protein

1

2

High-throughput

0.508

High

579456

DNLI1
DNA ligase 1

1

2

High-throughput

0.508

High

782022

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.508

High

782033

DPYL1
Dihydropyrimidinase-related protein 1

1

1

High-throughput

0.508

High

782036

ZYX
Zyxin

1

2

High-throughput

0.508

High

782046

ZN579
Zinc finger protein 579

1

2

High-throughput

0.508

High

782048

RIN3
Ras and Rab interactor 3

1

2

High-throughput

0.508

High

782052

TBB2B
Tubulin beta-2B chain

1

4

High-throughput

0.508

High

338066

EGFR
Epidermal growth factor receptor

1

3

Small-scale

0.501

High

782021

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.493

High

300885

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.486

High

316479

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.486

High

523568

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.486

High

602504

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.486

High

782028

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.486

High

782044

MON1A
Vacuolar fusion protein MON1 homolog A

1

0

High-throughput

0.486

High

782054

DUS21
Dual specificity protein phosphatase 21

1

0

High-throughput

0.486

High

782060

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.486

High

782062

PRAF1
Prenylated Rab acceptor protein 1

1

0

High-throughput

0.486

High

782065

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.486

High

428953

ADRB2
Beta-2 adrenergic receptor

1

8

Small-scale

0.481

High

782031

CUL4B
Cullin-4B

1

4

Small-scale

0.479

High

782035

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

782034

SCN5A
Sodium channel protein type 5 subunit alpha

1

0

High-throughput

0.438

High

782063

ZPI
Protein Z-dependent protease inhibitor

2

0

High-throughput

0.328

High

536324

GLU2B
Glucosidase 2 subunit beta

2

0

High-throughput

0.323

High

231851

MARH6
E3 ubiquitin-protein ligase MARCHF6

2

0

Small-scale

0.316

High

431187

CATB
Cathepsin B

2

0

High-throughput

0.307

High

421306

HYEP
Epoxide hydrolase 1

1

0

High-throughput

0.279

Low

782026

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.265

Low

782047

BBS10
Bardet-Biedl syndrome 10 protein

1

0

High-throughput

0.265

Low

782069

IR3IP
Immediate early response 3-interacting protein 1

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024