Protein: HEM3
Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)

Gene: HEM3, HMBS
Organism: Homo sapiens
Interactions: 14
UniProt ID: P08397

Gene Ontology (top 5):
GO:0004418 - hydroxymethylbilane synthase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006782 - protoporphyrinogen IX biosynthetic process
GO:0006783 - heme biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226306

PRKN
E3 ubiquitin-protein ligase parkin

3

0

High-throughput

0.613

High

439473

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

439463

HD
Huntingtin

1

0

High-throughput

0.493

High

439465

GSK3A
Glycogen synthase kinase-3 alpha

1

0

High-throughput

0.486

High

393961

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

439472

RANB9
Ran-binding protein 9

1

1

Small-scale

0.479

High

439474

XPO7
Exportin-7

1

1

High-throughput

0.479

High

439468

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

439469

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

439470

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

439467

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

3

0

High-throughput

0.347

High

439471

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

439464

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

439466

H31
Histone H3.1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024