Protein: PA24A
Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]

Gene: PA24A, PLA2G4A
Organism: Homo sapiens
Interactions: 61
UniProt ID: P47712

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001516 - prostaglandin biosynthetic process
GO:0002827 - positive regulation of T-helper 1 type immune response
GO:0004622 - lysophospholipase activity
GO:0004623 - phospholipase A2 activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

812815

S10AA
Protein S100-A10

3

3

Small-scale

0.866

High

566323

KPCA
Protein kinase C alpha type

1

12

Small-scale

0.785

High

776603

STAT3
Signal transducer and activator of transcription 3

1

2

High-throughput

0.691

High

537607

NCF1
Neutrophil cytosol factor 1

3

2

Small-scale

0.670

High

587798

NCF2
Neutrophil cytosol factor 2

3

5

Small-scale

0.664

High

812828

KAT5
Histone acetyltransferase KAT5

2

3

Small-scale

0.633

High

522853

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

Small-scale

0.618

High

685164

S10AB
Protein S100-A11

1

3

Small-scale

0.618

High

376189

ANXA1
Annexin A1

2

4

Small-scale

0.601

High

427486

ANXA2
Annexin A2

2

4

Small-scale

0.595

High

658841

MK01
Mitogen-activated protein kinase 1

2

3

Small-scale

0.595

High

377174

GCR
Glucocorticoid receptor

2

3

Small-scale

0.584

High

812824

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

2

Small-scale

0.573

High

396576

ITB3
Integrin beta-3

1

6

Small-scale

0.561

High

788161

CASP3
Caspase-3

1

7

Small-scale

0.536

High

812813

CASP7
Caspase-7

1

7

Small-scale

0.536

High

812823

CASP8
Caspase-8

1

7

Small-scale

0.536

High

431640

HS90A
Heat shock protein HSP 90-alpha

1

9

High-throughput

0.536

High

437980

HS90B
Heat shock protein HSP 90-beta

1

9

High-throughput

0.536

High

812812

PPP5
Serine/threonine-protein phosphatase 5

1

1

High-throughput

0.536

High

812822

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.536

High

812829

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.536

High

812833

RPAP3
RNA polymerase II-associated protein 3

1

6

High-throughput

0.536

High

812835

DJC17
DnaJ homolog subfamily C member 17

1

9

High-throughput

0.536

High

812836

SGT1
Protein SGT1 homolog

1

4

High-throughput

0.536

High

443387

VIME
Vimentin

1

2

Small-scale

0.515

High

574060

LOX12
Polyunsaturated fatty acid lipoxygenase ALOX12

1

1

Small-scale

0.515

High

616764

JAK1
Tyrosine-protein kinase JAK1

1

11

Small-scale

0.515

High

812826

DDX1
ATP-dependent RNA helicase DDX1

1

1

High-throughput

0.515

High

314260

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.513

High

812819

TF65
Transcription factor p65

1

1

Small-scale

0.508

High

812820

UBXN1
UBX domain-containing protein 1

1

2

Small-scale

0.508

High

667436

CASP1
Caspase-1

1

7

Small-scale

0.501

High

486879

MYBB
Myb-related protein B

1

0

Small-scale

0.493

High

812818

CAP1
Adenylyl cyclase-associated protein 1

1

0

Small-scale

0.486

High

226801

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

232806

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

401611

JUN
Transcription factor Jun

1

2

Small-scale

0.479

High

444861

ANXA5
Annexin A5

1

4

Small-scale

0.479

High

556809

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.479

High

625214

CDK2
Cyclin-dependent kinase 2

1

3

Small-scale

0.479

High

647505

MK03
Mitogen-activated protein kinase 3

1

3

Small-scale

0.479

High

718452

NOS2
Nitric oxide synthase, inducible

1

3

Small-scale

0.479

High

812814

ACTB
Actin, cytoplasmic 1

1

4

Small-scale

0.479

High

812816

ACTG
Actin, cytoplasmic 2

1

4

Small-scale

0.479

High

812817

ELF3
ETS-related transcription factor Elf-3

1

2

High-throughput

0.479

High

812821

EP300
Histone acetyltransferase p300

1

3

Small-scale

0.479

High

812825

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.479

High

386291

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

389783

CY24B
Cytochrome b-245 heavy chain

1

0

Small-scale

0.458

High

390762

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

590143

CCNA2
Cyclin-A2

1

0

Small-scale

0.458

High

722959

PGH2
Prostaglandin G/H synthase 2

1

0

Small-scale

0.458

High

812827

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

812832

EHD1
EH domain-containing protein 1

1

0

Small-scale

0.458

High

439933

ITA2B
Integrin alpha-IIb

1

2

Small-scale

0.457

High

346192

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.445

High

812831

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.445

High

380942

SHBG
Sex hormone-binding globulin

1

1

Small-scale

0.439

High

812830

BORC6
BLOC-1-related complex subunit 6

1

0

Small-scale

0.265

Low

812834

XAGE1
X antigen family member 1

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024