Protein: UBE2B
Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B)

Gene: UBE2B
Organism: Homo sapiens
Interactions: 60
UniProt ID: P63146

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0000785 - chromatin
GO:0001701 - in utero embryonic development
GO:0001741 - XY body
GO:0004842 - ubiquitin-protein transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

927780

RAD18
E3 ubiquitin-protein ligase RAD18

22

6

Small-scale

0.991

High

607054

UBA1
Ubiquitin-like modifier-activating enzyme 1

10

19

Small-scale

0.974

High

927757

BRE1A
E3 ubiquitin-protein ligase BRE1A

7

16

Small-scale

0.970

High

256239

BRE1B
E3 ubiquitin-protein ligase BRE1B

4

16

Small-scale

0.888

High

475597

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

20

Small-scale

0.878

High

828975

UBE2A
Ubiquitin-conjugating enzyme E2 A

3

15

Small-scale

0.861

High

927744

UBE2B
Ubiquitin-conjugating enzyme E2 B

3

15

Small-scale

0.858

High

517180

PCNA
Proliferating cell nuclear antigen

2

4

Small-scale

0.778

High

927771

HERP2
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

2

0

High-throughput

0.742

High

927762

UBR1
E3 ubiquitin-protein ligase UBR1

4

14

Small-scale

0.692

High

927763

UBR2
E3 ubiquitin-protein ligase UBR2

4

14

Small-scale

0.680

High

927760

UBR3
E3 ubiquitin-protein ligase UBR3

3

14

Small-scale

0.658

High

227115

PRKN
E3 ubiquitin-protein ligase parkin

1

20

Small-scale

0.647

High

304114

UBR5
E3 ubiquitin-protein ligase UBR5

1

20

Small-scale

0.647

High

927745

RNF4
E3 ubiquitin-protein ligase RNF4

1

20

Small-scale

0.647

High

927756

RC3H1
Roquin-1

1

6

Small-scale

0.647

High

927776

RN167
E3 ubiquitin-protein ligase RNF167

1

20

Small-scale

0.647

High

927777

TRI45
E3 ubiquitin-protein ligase TRIM45

1

20

Small-scale

0.647

High

927778

RC3H2
Roquin-2

1

7

Small-scale

0.647

High

927752

HLTF
Helicase-like transcription factor

1

10

Small-scale

0.646

High

927753

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

8

Small-scale

0.646

High

716973

CTNB1
Catenin beta-1

2

1

Small-scale

0.639

High

927749

BIRC2
Baculoviral IAP repeat-containing protein 2

1

20

Small-scale

0.621

High

927784

ZMYM2
Zinc finger MYM-type protein 2

2

1

Small-scale

0.620

High

927754

H2A2C
Histone H2A type 2-C

2

4

Small-scale

0.619

High

927746

MDM2
E3 ubiquitin-protein ligase Mdm2

1

13

Small-scale

0.618

High

927786

HERC5
E3 ISG15--protein ligase HERC5

1

20

Small-scale

0.618

High

927755

UBR4
E3 ubiquitin-protein ligase UBR4

2

9

Small-scale

0.576

High

927775

SKI8
Superkiller complex protein 8

1

1

Small-scale

0.575

High

800339

CBX5
Chromobox protein homolog 5

1

3

Small-scale

0.561

High

927789

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

927761

H2A3
Histone H2A type 3

1

4

Small-scale

0.516

High

804098

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

2

Small-scale

0.501

High

927767

H2B1A
Histone H2B type 1-A

1

7

Small-scale

0.501

High

927751

DPYL1
Dihydropyrimidinase-related protein 1

1

1

High-throughput

0.494

High

927768

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.493

High

927750

TRI14
Tripartite motif-containing protein 14

1

20

High-throughput

0.481

High

246204

NBN
Nibrin

1

2

Small-scale

0.479

High

386483

P53
Cellular tumor antigen p53

1

3

Small-scale

0.479

High

927747

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.479

High

927770

SLF1
SMC5-SMC6 complex localization factor protein 1

1

8

Small-scale

0.479

High

927772

WAC
WW domain-containing adapter protein with coiled-coil

1

1

Small-scale

0.479

High

927773

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

High-throughput

0.479

High

927779

SYSM
Serine--tRNA ligase, mitochondrial

1

1

Small-scale

0.479

High

927782

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

20

Small-scale

0.479

High

927785

NPS3A
Protein NipSnap homolog 3A

1

3

Small-scale

0.479

High

927787

POLH
DNA polymerase eta

1

1

Small-scale

0.479

High

927783

COKA1

1

1

High-throughput

0.470

High

927774

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.458

High

927766

IRF7
Interferon regulatory factor 7

1

1

High-throughput

0.457

High

927758

CDC73
Parafibromin

1

2

Small-scale

0.445

High

927759

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

Small-scale

0.445

High

927764

LEO1
RNA polymerase-associated protein LEO1

1

3

Small-scale

0.445

High

927765

RTF1
RNA polymerase-associated protein RTF1 homolog

1

2

Small-scale

0.445

High

927769

NIPS1
Protein NipSnap homolog 1

1

3

Small-scale

0.437

High

927781

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

1

1

Small-scale

0.437

High

927788

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

1

Small-scale

0.437

High

657903

PEX2
Peroxisome biogenesis factor 2

1

2

Small-scale

0.407

High

927748

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024