Protein: SMYD5
Histone-lysine N-trimethyltransferase SMYD5 (EC 2.1.1.372) (Protein NN8-4AG) (Retinoic acid-induced protein 15) (SET and MYND domain-containing protein 5) ([histone H4]-lysine20 N-trimethyltransferase SMYD5)

Gene: SMYD5
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q6GMV2

Gene Ontology (top 5):
GO:0032259 - methylation
GO:0042799 - histone H4K20 methyltransferase activity
GO:0045814 - negative regulation of gene expression, epigenetic
GO:0046872 - metal ion binding
GO:0140943 - histone H4K20 trimethyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1151489

ZN417
Zinc finger protein 417

2

1

High-throughput

0.606

High

1151490

ZN587
Zinc finger protein 587

2

1

High-throughput

0.606

High

917439

H4
Histone H4

1

3

Small-scale

0.579

High

934878

H31
Histone H3.1

1

7

Small-scale

0.579

High

1151488

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.553

High

707658

H2B1B
Histone H2B type 1-B

1

0

Small-scale

0.541

High

946546

DCD
Dermcidin

1

0

High-throughput

0.513

High

1109553

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

1151492

ZN430
Zinc finger protein 430

1

0

High-throughput

0.513

High

1151493

ZN446
Zinc finger protein 446

1

0

High-throughput

0.513

High

924323

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

High-throughput

0.489

High

1151495

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.489

High

971215

H11
Histone H1.1

1

1

Small-scale

0.457

High

227766

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.437

High

360041

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.437

High

524953

XRCC5
X-ray repair cross-complementing protein 5

1

0

High-throughput

0.279

Low

841087

TUB
Tubby protein homolog

1

0

High-throughput

0.279

Low

1099358

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

1151494

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.279

Low

1068209

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.269

Low

244568

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

504244

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

720695

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

850086

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

Small-scale

0.249

Low

1151491

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024