HitPredict - High confidence protein-protein interactions

Protein: ISL1
Insulin gene enhancer protein ISL-1 (Islet-1)

Gene: ISL1
Organism: Mus musculus
Interactions: 8
UniProt ID: P61372

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001046 - core promoter sequence-specific DNA binding

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
961497	LDB1 LIM domain-binding protein 1	3	20	Small-scale	0.814	High
895872	LHX3 LIM/homeobox protein Lhx3	1	17	Small-scale	0.713	High
237321	LDB2 LIM domain-binding protein 2	1	20	High-throughput	0.698	High
961501	SSBP2 Single-stranded DNA-binding protein 2	1	20	High-throughput	0.541	High
961498	BRE1B E3 ubiquitin-protein ligase BRE1B	1	6	Small-scale	0.479	High
961499	BRE1A E3 ubiquitin-protein ligase BRE1A	1	5	Small-scale	0.479	High
961502	SSBP3 Single-stranded DNA-binding protein 3	1	20	Small-scale	0.479	High
961500	FACD2 Fanconi anemia group D2 protein homolog	1	0	High-throughput	0.458	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025