Protein: ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (EC 1.2.4.1) (Pyruvate dehydrogenase complex component E1 beta) (PDHE1-B)

Gene: ODPB, PDB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 122
UniProt ID: P32473

Gene Ontology (top 5):
GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0042645 - mitochondrial nucleoid

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520802

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

5

8

High-throughput

0.922

High

558593

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

4

15

High-throughput

0.892

High

452975

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

4

3

High-throughput

0.691

High

560329

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

4

9

High-throughput

0.691

High

690655

PREP
Presequence protease, mitochondrial

3

3

High-throughput

0.662

High

690665

TCM62
Mitochondrial chaperone TCM62

3

3

High-throughput

0.643

High

690652

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

2

2

High-throughput

0.621

High

596625

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

10

High-throughput

0.618

High

635961

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

2

2

High-throughput

0.611

High

690650

DUR1
Urea amidolyase [Includes: Urea carboxylase

2

0

High-throughput

0.595

High

680526

HS104
Heat shock protein 104

3

2

Small-scale

0.585

High

478011

HSP77
Import motor subunit, mitochondrial

2

3

High-throughput

0.584

High

690656

HSP78
Heat shock protein 78, mitochondrial

2

2

High-throughput

0.584

High

587997

HSP60
Heat shock protein 60, mitochondrial

2

2

High-throughput

0.571

High

690691

RM22
Large ribosomal subunit protein uL22m

2

1

High-throughput

0.571

High

690718

PRP46
Pre-mRNA-splicing factor PRP46

2

4

High-throughput

0.567

High

690681

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.563

High

690722

CMR1
DNA damage-binding protein CMR1

2

5

High-throughput

0.533

High

690683

AIM23
Altered inheritance of mitochondria protein 23, mitochondrial

1

0

High-throughput

0.493

High

543388

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

567949

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

581273

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

8

High-throughput

0.479

High

675796

RF1M
Peptide chain release factor 1, mitochondrial

1

3

High-throughput

0.479

High

690712

CDC73
Cell division control protein 73

1

1

High-throughput

0.470

High

690713

ADY3
Accumulates dyads protein 3

1

2

High-throughput

0.470

High

375318

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

410775

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

423591

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

584136

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.458

High

602433

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

607461

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.458

High

641314

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

0

High-throughput

0.458

High

650212

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.458

High

679527

RM09
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.458

High

690653

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

0

High-throughput

0.458

High

690654

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

690660

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

690663

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

690667

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

690668

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

Small-scale

0.458

High

690671

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

690673

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

0

High-throughput

0.458

High

690678

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

690679

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

690687

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.458

High

690688

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

690689

ALAM
Probable alanine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

690692

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

690698

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

690699

ESP1
Separin

1

0

High-throughput

0.458

High

690703

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

690704

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

690707

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

690720

RM23
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.458

High

690723

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

477180

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

High-throughput

0.457

High

424402

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

493454

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

356325

H4
Histone H4

1

1

High-throughput

0.437

High

365979

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.437

High

627815

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

661632

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

687864

NUD1
Protein NUD1

1

1

High-throughput

0.437

High

690662

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

690666

GID4
Vacuolar import and degradation protein 24

1

1

High-throughput

0.437

High

690670

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.437

High

690694

H3
Histone H3

1

1

High-throughput

0.437

High

690700

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

690702

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

690715

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

690717

ARP8
Actin-like protein ARP8

1

1

High-throughput

0.437

High

690719

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

367851

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

690690

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.426

High

490643

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.407

High

510612

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.407

High

687324

EF2
Elongation factor 2

1

2

High-throughput

0.407

High

690674

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.407

High

687904

IMB3
Importin subunit beta-3

2

0

High-throughput

0.324

High

690695

AP1M1
AP-1 complex subunit mu-1-I

2

0

High-throughput

0.307

High

690696

MCE1
mRNA-capping enzyme subunit alpha

2

0

High-throughput

0.307

High

690705

NTE1
Lysophospholipase NTE1

2

0

High-throughput

0.307

High

340069

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.279

Low

659764

SBA1
Co-chaperone protein SBA1

1

0

High-throughput

0.265

Low

690708

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

0

High-throughput

0.265

Low

252696

MRP10
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low

399372

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.249

Low

413375

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

470928

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472080

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

481482

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.249

Low

524222

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

557941

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

619429

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

633836

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

690657

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.249

Low

690658

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

690659

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

690661

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

690664

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

690669

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

690672

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

690675

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.249

Low

690676

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

690677

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

690680

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.249

Low

690684

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

690685

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

690686

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

690693

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

690697

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

690701

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

690706

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.249

Low

690709

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

690710

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

555894

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

690651

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.232

Low

690682

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low

690711

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.232

Low

690714

AB140
tRNA(Thr)

1

0

High-throughput

0.232

Low

690716

MAM3
Protein MAM3

1

0

High-throughput

0.232

Low

690721

RLF2
Chromatin assembly factor 1 subunit p90

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024