Protein: LSM3
U6 snRNA-associated Sm-like protein LSm3 (SmX4 protein)

Gene: LSM3
Organism: Saccharomyces cerevisiae S288C
Interactions: 122
UniProt ID: P57743

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

810530

LSM1
Sm-like protein LSm1

15

20

Small-scale

0.983

High

746331

LSM2
U6 snRNA-associated Sm-like protein LSm2

12

20

Small-scale

0.980

High

767815

LSM4
U6 snRNA-associated Sm-like protein LSm4

9

20

Small-scale

0.974

High

884830

LSM6
U6 snRNA-associated Sm-like protein LSm6

9

20

Small-scale

0.973

High

635906

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

10

10

Small-scale

0.972

High

768245

LSM5
U6 snRNA-associated Sm-like protein LSm5

9

17

Small-scale

0.972

High

865977

LSM7
U6 snRNA-associated Sm-like protein LSm7

8

20

Small-scale

0.968

High

837114

PRP24
U4/U6 snRNA-associated-splicing factor PRP24

7

9

Small-scale

0.956

High

811659

LSM8
U6 snRNA-associated Sm-like protein LSm8

6

20

Small-scale

0.945

High

731753

SN114
Pre-mRNA-splicing factor SNU114

6

14

Small-scale

0.938

High

884824

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

5

12

Small-scale

0.915

High

766937

RSMB
Small nuclear ribonucleoprotein-associated protein B

5

19

Small-scale

0.908

High

884818

LSM3
U6 snRNA-associated Sm-like protein LSm3

4

19

Small-scale

0.906

High

704699

PRP8
Pre-mRNA-splicing factor 8

4

9

Small-scale

0.875

High

884839

RUXE
Small nuclear ribonucleoprotein E

2

13

Small-scale

0.768

High

884829

SMD2
Small nuclear ribonucleoprotein Sm D2

2

14

Small-scale

0.754

High

697241

BRR2
Pre-mRNA-splicing helicase BRR2

8

20

Small-scale

0.741

High

605117

XRN1
5'-3' exoribonuclease 1

7

4

Small-scale

0.741

High

795403

SMD3
Small nuclear ribonucleoprotein Sm D3

2

20

High-throughput

0.737

High

762005

DHH1
ATP-dependent RNA helicase DHH1

5

12

Small-scale

0.708

High

589091

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

5

20

Small-scale

0.706

High

586432

PRP6
Pre-mRNA-splicing factor 6

4

20

Small-scale

0.678

High

830819

PRP31
Pre-mRNA-processing factor 31

4

10

Small-scale

0.678

High

884841

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

11

Small-scale

0.672

High

862699

DCP2
m7GpppN-mRNA hydrolase

3

1

High-throughput

0.647

High

884834

DIB1
Spliceosomal protein DIB1

3

6

Small-scale

0.633

High

368314

EF1A
Elongation factor 1-alpha

1

2

Small-scale

0.618

High

884821

SMD1
Small nuclear ribonucleoprotein Sm D1

1

12

High-throughput

0.618

High

884844

DCP1
mRNA-decapping enzyme subunit 1

2

3

Small-scale

0.601

High

797254

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

Small-scale

0.586

High

675766

RENT1
ATP-dependent helicase NAM7

2

8

Small-scale

0.584

High

586509

PRP9
Pre-mRNA-splicing factor PRP9

1

5

High-throughput

0.575

High

884837

RU2A
U2 small nuclear ribonucleoprotein A'

1

11

High-throughput

0.575

High

499036

RL4A
Large ribosomal subunit protein uL4A

2

1

Small-scale

0.571

High

494698

HSP72
Heat shock protein SSA2

2

6

High-throughput

0.552

High

512341

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

728300

DEF1
RNA polymerase II degradation factor 1

1

2

High-throughput

0.541

High

636168

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.518

High

680055

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

High-throughput

0.518

High

713714

NOT4
General negative regulator of transcription subunit 4

1

0

High-throughput

0.518

High

766468

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.515

High

884827

SWR1
Helicase SWR1

1

3

High-throughput

0.515

High

500615

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.508

High

603003

BAS1
Myb-like DNA-binding protein BAS1

1

3

High-throughput

0.508

High

698562

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

1

High-throughput

0.508

High

727630

LRG1
Rho-GTPase-activating protein LRG1

1

3

High-throughput

0.508

High

820018

BRO1
Vacuolar-sorting protein BRO1

1

1

High-throughput

0.508

High

645590

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.486

High

748847

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.486

High

770438

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.486

High

424898

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.479

High

544237

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

634726

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

696885

RML2
Large ribosomal subunit protein uL2m

1

3

High-throughput

0.479

High

735292

RM07
Large ribosomal subunit protein uL5m

1

3

High-throughput

0.479

High

829663

RL4B
Large ribosomal subunit protein uL4B

1

1

Small-scale

0.479

High

884825

RM01
Large ribosomal subunit protein uL1m

1

3

High-throughput

0.479

High

884831

MHR1
Large ribosomal subunit protein mL67

1

3

High-throughput

0.479

High

884836

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.479

High

884838

CLF1
Pre-mRNA-splicing factor CLF1

1

20

Small-scale

0.479

High

691839

EI2BB
Translation initiation factor eIF2B subunit beta

1

3

High-throughput

0.464

High

747561

AIM3
Altered inheritance of mitochondria protein 3

1

4

High-throughput

0.464

High

812605

IML1
Vacuolar membrane-associated protein IML1

1

2

High-throughput

0.464

High

860930

YG2W
Uncharacterized protein YGR111W

1

0

High-throughput

0.458

High

884843

NOT5
General negative regulator of transcription subunit 5

1

1

High-throughput

0.457

High

376893

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

6

High-throughput

0.445

High

478428

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.445

High

492114

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

560766

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.445

High

629020

SCJ1
DnaJ-related protein SCJ1

1

2

High-throughput

0.445

High

633475

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

692336

PRP19
Pre-mRNA-processing factor 19

1

17

Small-scale

0.445

High

692416

PRP21
Pre-mRNA-splicing factor PRP21

1

7

High-throughput

0.445

High

705522

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

742934

GBLP
Small ribosomal subunit protein RACK1

1

9

High-throughput

0.445

High

763241

PRP39
Pre-mRNA-processing factor 39

1

20

High-throughput

0.445

High

836921

SF3B1
U2 snRNP component HSH155

1

9

High-throughput

0.445

High

884819

PRP38
Pre-mRNA-splicing factor 38

1

1

High-throughput

0.445

High

884822

CUS1
Cold sensitive U2 snRNA suppressor 1

1

6

High-throughput

0.445

High

884826

RSE1
Pre-mRNA-splicing factor RSE1

1

5

High-throughput

0.445

High

884832

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.445

High

884835

PRP11
Pre-mRNA-splicing factor PRP11

1

5

High-throughput

0.445

High

884840

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.445

High

520546

RM02
Large ribosomal subunit protein bL27m

1

3

High-throughput

0.437

High

534499

RM31
Large ribosomal subunit protein mL60

1

3

High-throughput

0.437

High

589395

RM33
Large ribosomal subunit protein uL30m

1

3

High-throughput

0.437

High

607436

RM08
Large ribosomal subunit protein bL17m

1

3

High-throughput

0.437

High

607503

RM20
Large ribosomal subunit protein mL58

1

3

High-throughput

0.437

High

615624

RM25
Large ribosomal subunit protein mL59

1

3

High-throughput

0.437

High

629871

RM32
Large ribosomal subunit protein bL32m

1

2

High-throughput

0.437

High

635390

IMG1
Large ribosomal subunit protein bL19m

1

3

High-throughput

0.437

High

635795

IMG2
Large ribosomal subunit protein mL49

1

3

High-throughput

0.437

High

679579

RM09
Large ribosomal subunit protein uL3m

1

4

High-throughput

0.437

High

689535

RM41
Large ribosomal subunit protein uL23m

1

3

High-throughput

0.437

High

710685

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

1

High-throughput

0.437

High

729815

RM38
Large ribosomal subunit protein uL14m

1

3

High-throughput

0.437

High

735162

RM03
Large ribosomal subunit protein mL44

1

3

High-throughput

0.437

High

735358

RM10
Large ribosomal subunit protein uL15m

1

3

High-throughput

0.437

High

735528

RM24
Large ribosomal subunit protein bL28m

1

3

High-throughput

0.437

High

735572

RM27
Large ribosomal subunit protein mL41

1

3

High-throughput

0.437

High

735623

RM28
Large ribosomal subunit protein mL40

1

3

High-throughput

0.437

High

735686

RM17
Large ribosomal subunit protein mL46

1

3

High-throughput

0.437

High

735739

RM36
Large ribosomal subunit protein bL31m

1

2

High-throughput

0.437

High

735803

RM39
Large ribosomal subunit protein bL33m

1

3

High-throughput

0.437

High

735841

RM40
Large ribosomal subunit protein uL24m

1

3

High-throughput

0.437

High

743372

RM16
Large ribosomal subunit protein uL16m

1

3

High-throughput

0.437

High

777369

RN49
Large ribosomal subunit protein bL21m

1

3

High-throughput

0.437

High

852254

RL4P
Large ribosomal subunit protein uL4m

1

3

High-throughput

0.437

High

860343

EIF2A
Eukaryotic translation initiation factor 2A

1

4

High-throughput

0.437

High

864410

RM50
Large ribosomal subunit protein bL9m

1

3

High-throughput

0.437

High

865707

RM22
Large ribosomal subunit protein uL22m

1

3

High-throughput

0.437

High

884820

RM13
Large ribosomal subunit protein mL50

1

3

High-throughput

0.437

High

884833

RM35
Large ribosomal subunit protein mL38

1

3

High-throughput

0.437

High

884842

RM23
Large ribosomal subunit protein uL13m

1

3

High-throughput

0.437

High

399591

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.426

High

407242

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

692265

PT309
Pentatricopeptide repeat-containing protein PET309, mitochondrial

1

0

High-throughput

0.265

Low

884828

YL281
Uncharacterized peptide chain release factor-like protein YLR281C, mitochondrial

1

0

High-throughput

0.265

Low

252722

MRP10
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low

520443

RT13
Small ribosomal subunit protein mS27

1

0

High-throughput

0.249

Low

884823

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024