Protein: DEPD5
GATOR1 complex protein DEPDC5 (DEP domain-containing protein 5)

Gene: DEPD5, DEPDC5
Organism: Homo sapiens
Interactions: 35
UniProt ID: O75140

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0010508 - positive regulation of autophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

254989

NPRL2
GATOR1 complex protein NPRL2

8

2

Small-scale

0.970

High

254996

WDR24
GATOR2 complex protein WDR24

4

4

Small-scale

0.886

High

254986

WDR59
GATOR2 complex protein WDR59

2

4

Small-scale

0.754

High

254980

NPRL3
GATOR1 complex protein NPRL3

6

1

Small-scale

0.735

High

254999

RRAGC
Ras-related GTP-binding protein C

3

4

Small-scale

0.676

High

254983

SZT2
KICSTOR complex protein SZT2

4

0

Small-scale

0.670

High

255001

MIOS
GATOR2 complex protein MIOS

3

3

Small-scale

0.656

High

254988

RRAGA
Ras-related GTP-binding protein A

3

4

Small-scale

0.646

High

254991

ITFG2
KICSTOR complex protein ITFG2

3

0

Small-scale

0.638

High

254994

KICS2
KICSTOR subunit 2

3

0

Small-scale

0.638

High

255004

KPTN
KICSTOR complex protein kaptin

3

0

Small-scale

0.638

High

254984

RRAGB
Ras-related GTP-binding protein B

2

4

Small-scale

0.619

High

254981

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

1

High-throughput

0.606

High

254982

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

2

0

High-throughput

0.602

High

254970

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

0

High-throughput

0.580

High

254975

TCPG
T-complex protein 1 subunit gamma

2

0

High-throughput

0.580

High

254995

MTMR9
Myotubularin-related protein 9

2

0

High-throughput

0.580

High

255002

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

1

High-throughput

0.553

High

254979

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.536

High

254972

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.513

High

254990

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.493

High

254978

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.479

High

255000

RRAGD
Ras-related GTP-binding protein D

1

4

Small-scale

0.479

High

254985

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

254973

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

Small-scale

0.458

High

254977

SESN2
Sestrin-2

1

0

Small-scale

0.458

High

254992

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

255003

FEM1B
Protein fem-1 homolog B

1

0

Small-scale

0.458

High

254976

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

254971

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

254993

ZN414
Zinc finger protein 414

2

0

High-throughput

0.318

High

254987

DPPA3
Developmental pluripotency-associated protein 3

2

0

High-throughput

0.316

High

254998

SYT17
Synaptotagmin-17

2

0

High-throughput

0.316

High

254974

RBTN1
Rhombotin-1

1

0

High-throughput

0.279

Low

254997

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024