Protein: CDN1C
Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57Kip2)

Gene: CDN1C, CDKN1C
Organism: Homo sapiens
Interactions: 38
UniProt ID: P49918

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007049 - cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625237

CDK2
Cyclin-dependent kinase 2

7

20

High-throughput

0.968

High

622403

CCND1
G1/S-specific cyclin-D1

5

20

Small-scale

0.931

High

590146

CCNA2
Cyclin-A2

5

15

Small-scale

0.927

High

673132

CCND3
G1/S-specific cyclin-D3

4

20

High-throughput

0.903

High

515378

CDK4
Cyclin-dependent kinase 4

3

20

Small-scale

0.870

High

414825

CDK1
Cyclin-dependent kinase 1

3

20

High-throughput

0.861

High

673041

CCND2
G1/S-specific cyclin-D2

3

20

High-throughput

0.861

High

836898

CDK3
Cyclin-dependent kinase 3

3

20

High-throughput

0.861

High

836899

CDK6
Cyclin-dependent kinase 6

3

20

High-throughput

0.861

High

538496

CCNB1
G2/mitotic-specific cyclin-B1

2

15

Small-scale

0.789

High

681744

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

Small-scale

0.724

High

303838

CCNB2
G2/mitotic-specific cyclin-B2

1

15

High-throughput

0.691

High

331633

CCNE2
G1/S-specific cyclin-E2

1

20

Small-scale

0.656

High

517132

PCNA
Proliferating cell nuclear antigen

2

5

Small-scale

0.631

High

836902

SKP2
S-phase kinase-associated protein 2

2

6

Small-scale

0.624

High

800725

MK08
Mitogen-activated protein kinase 8

1

18

Small-scale

0.618

High

836895

CDK7
Cyclin-dependent kinase 7

1

20

Small-scale

0.618

High

836896

CDK9
Cyclin-dependent kinase 9

1

20

Small-scale

0.618

High

486883

MYBB
Myb-related protein B

1

1

Small-scale

0.561

High

545947

MYOD1
Myoblast determination protein 1

1

2

Small-scale

0.561

High

836893

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

4

Small-scale

0.561

High

708841

MCM7
DNA replication licensing factor MCM7

1

5

Small-scale

0.552

High

771837

VHL
von Hippel-Lindau disease tumor suppressor

1

2

Small-scale

0.552

High

836897

LIMK1
LIM domain kinase 1

1

3

Small-scale

0.552

High

259930

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

3

High-throughput

0.536

High

414215

RB
Retinoblastoma-associated protein

1

3

Small-scale

0.501

High

836907

FXL12
F-box/LRR-repeat protein 12

1

6

Small-scale

0.488

High

386324

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

660099

RBL1
Retinoblastoma-like protein 1

1

3

Small-scale

0.479

High

836894

ASCL1
Achaete-scute homolog 1

1

2

Small-scale

0.479

High

836900

E2F1
Transcription factor E2F1

1

4

Small-scale

0.479

High

836901

EP300
Histone acetyltransferase p300

1

7

Small-scale

0.479

High

836903

NDF1
Neurogenic differentiation factor 1

1

2

Small-scale

0.479

High

836904

FBX22
F-box only protein 22

1

1

Small-scale

0.479

High

836905

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.479

High

836906

NDF6
Neurogenic differentiation factor 6

1

2

Small-scale

0.479

High

624812

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High


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Last updated: 15 Jul 2024