Protein: CAN3
Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)

Gene: CAN3, CAPN3
Organism: Homo sapiens
Interactions: 50
UniProt ID: P20807

Gene Ontology (top 5):
GO:0003824 - catalytic activity
GO:0004198 - calcium-dependent cysteine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

595836

TITIN
Titin

4

8

Small-scale

0.883

High

595808

CAN3
Calpain-3

3

14

Small-scale

0.849

High

595839

NTAQ1
Protein N-terminal glutamine amidohydrolase

3

0

High-throughput

0.646

High

373671

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.618

High

595828

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

5

High-throughput

0.606

High

595829

C102B
Coiled-coil domain-containing protein 102B

2

5

High-throughput

0.606

High

595830

RUFY3
Protein RUFY3

2

6

High-throughput

0.606

High

595838

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

2

1

High-throughput

0.606

High

595841

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

3

High-throughput

0.606

High

595831

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.589

High

595833

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.580

High

595837

TRI63
E3 ubiquitin-protein ligase TRIM63

1

9

High-throughput

0.568

High

358970

CRYAB
Alpha-crystallin B chain

1

2

High-throughput

0.541

High

439226

MMP2
72 kDa type IV collagenase

1

4

High-throughput

0.541

High

572854

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.541

High

595812

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

595815

MYPC1
Myosin-binding protein C, slow-type

1

5

High-throughput

0.541

High

595816

UBE3A
Ubiquitin-protein ligase E3A

1

8

High-throughput

0.541

High

595818

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.541

High

595819

MYBPH
Myosin-binding protein H

1

4

High-throughput

0.541

High

595825

AMOT
Angiomotin

1

6

High-throughput

0.541

High

595834

CMYA5
Cardiomyopathy-associated protein 5

1

11

High-throughput

0.541

High

595844

RN167
E3 ubiquitin-protein ligase RNF167

1

1

High-throughput

0.541

High

595824

PPCEL
Prolyl endopeptidase-like

1

0

High-throughput

0.518

High

595840

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.518

High

595847

POMP
Proteasome maturation protein

1

0

High-throughput

0.518

High

595823

H31T
Histone H3.1t

1

1

High-throughput

0.515

High

413826

GELS
Gelsolin

1

1

High-throughput

0.515

High

527293

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.515

High

595809

FGFR3
Fibroblast growth factor receptor 3

1

5

High-throughput

0.515

High

595813

CASP6
Caspase-6

1

4

High-throughput

0.515

High

595814

RAN
GTP-binding nuclear protein Ran

1

3

High-throughput

0.515

High

595817

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.515

High

595846

UBQL1
Ubiquilin-1

1

5

High-throughput

0.515

High

595848

SHLB1
Endophilin-B1

1

4

High-throughput

0.515

High

595822

FLNC
Filamin-C

1

11

Small-scale

0.501

High

595826

FND3B
Fibronectin type III domain-containing protein 3B

1

7

High-throughput

0.494

High

595811

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

595820

BYST
Bystin

1

0

High-throughput

0.493

High

595821

VEZF1
Vascular endothelial zinc finger 1

1

0

High-throughput

0.493

High

595832

ZN410
Zinc finger protein 410

1

0

High-throughput

0.493

High

595835

CEP76
Centrosomal protein of 76 kDa

1

1

High-throughput

0.481

High

595843

TRI55
Tripartite motif-containing protein 55

1

10

High-throughput

0.481

High

595810

PSA3
Proteasome subunit alpha type-3

1

1

Small-scale

0.479

High

595842

TRI54
Tripartite motif-containing protein 54

1

9

High-throughput

0.479

High

263516

PR40A
Pre-mRNA-processing factor 40 homolog A

1

8

High-throughput

0.470

High

595845

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.327

High

473741

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

0

High-throughput

0.282

High

595827

ENPLL
Putative endoplasmin-like protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024