Protein: MCR1
NADH-cytochrome b5 reductase 2 (EC 1.6.2.2) (Mitochondrial cytochrome b reductase) (p34/p32) [Cleaved into: NADH-cytochrome b5 reductase p34 form; NADH-cytochrome b5 reductase p32 form]

Gene: MCR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P36060

Gene Ontology (top 5):
GO:0003954 - NADH dehydrogenase activity
GO:0004128 - cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005758 - mitochondrial intermembrane space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

493669

HSP72
Heat shock protein SSA2

2

10

Small-scale

0.619

High

732037

RSP5
E3 ubiquitin-protein ligase RSP5

2

3

Small-scale

0.602

High

543547

HSC82
ATP-dependent molecular chaperone HSC82

2

11

Small-scale

0.584

High

732046

TOM22
Mitochondrial import receptor subunit TOM22

2

1

High-throughput

0.584

High

627920

SIS1
Protein SIS1

2

7

Small-scale

0.570

High

490879

HSP71
Heat shock protein SSA1

2

10

Small-scale

0.565

High

732050

ALO
D-arabinono-1,4-lactone oxidase

1

1

High-throughput

0.541

High

510899

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

Small-scale

0.521

High

732038

SSB2
Ribosome-associated molecular chaperone SSB2

2

9

Small-scale

0.521

High

366113

HSP82
ATP-dependent molecular chaperone HSP82

1

11

Small-scale

0.512

High

549724

STI1
Heat shock protein STI1

1

6

Small-scale

0.512

High

633130

MAS5
Mitochondrial protein import protein MAS5

1

5

Small-scale

0.512

High

680615

HS104
Heat shock protein 104

1

6

Small-scale

0.512

High

732040

DJP1
DnaJ-like protein 1

1

6

Small-scale

0.501

High

732051

CDC14
Tyrosine-protein phosphatase CDC14

1

3

High-throughput

0.489

High

626430

ERG6
Sterol 24-C-methyltransferase ERG6

1

2

High-throughput

0.481

High

333310

CYC1
Cytochrome c isoform 1

1

1

High-throughput

0.479

High

423006

TOM70
Mitochondrial import receptor subunit TOM70

1

4

High-throughput

0.479

High

478089

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

588032

HSP60
Heat shock protein 60, mitochondrial

1

7

Small-scale

0.479

High

692493

ZUO1
Zuotin

1

5

Small-scale

0.479

High

699845

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

705042

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.479

High

732028

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

732033

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

7

Small-scale

0.479

High

732035

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

1

High-throughput

0.479

High

732039

SNL1
HSP70 co-chaperone SNL1

1

2

Small-scale

0.479

High

732047

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

732052

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

1

High-throughput

0.479

High

732059

SCC1
Sister chromatid cohesion protein 1

1

1

Small-scale

0.479

High

732062

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

1

High-throughput

0.479

High

732063

MIC10
MICOS complex subunit MIC10

1

1

Small-scale

0.479

High

732056

PIN3
[PSI+] inducibility protein 3

1

1

High-throughput

0.464

High

333372

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.458

High

357251

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

373231

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

424066

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

Small-scale

0.458

High

561187

OM45
Mitochondrial outer membrane protein OM45

1

0

High-throughput

0.458

High

565155

CBF1
Centromere-binding protein 1

1

0

High-throughput

0.458

High

601433

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.458

High

732030

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

732034

OM14
Mitochondrial outer membrane protein OM14

1

0

High-throughput

0.458

High

732041

ERG10
Acetyl-CoA acetyltransferase

1

0

High-throughput

0.458

High

732049

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

732054

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

565540

PHO85
Cyclin-dependent protein kinase PHO85

1

4

High-throughput

0.457

High

341992

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.445

High

424463

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

707837

GCN1
eIF-2-alpha kinase activator GCN1

1

2

High-throughput

0.445

High

732029

PET10
Protein PET10

1

1

High-throughput

0.439

High

605333

HSP74
Heat shock protein SSA4

1

10

Small-scale

0.437

High

661908

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

694466

HSP7F
Heat shock protein homolog SSE1

1

16

Small-scale

0.437

High

731098

LHS1
Heat shock protein 70 homolog LHS1

1

11

Small-scale

0.437

High

732032

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

732036

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

732043

VTC2
Vacuolar transporter chaperone complex subunit 2

1

1

Small-scale

0.437

High

732044

VTC4
Vacuolar transporter chaperone complex subunit 4

1

1

Small-scale

0.437

High

732045

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

732053

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

367946

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

340109

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.407

High

454282

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.407

High

555972

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.407

High

732042

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

732061

AHA1
Hsp90 co-chaperone AHA1

1

0

Small-scale

0.292

High

703193

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

732060

HSP42
Heat shock protein 42

1

0

Small-scale

0.261

Low

660314

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

696937

IES6
Chromatin-remodeling complex subunit IES6

1

0

High-throughput

0.249

Low

732027

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

732055

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

732057

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.249

Low

732058

FEX1
Fluoride export protein 1

1

0

High-throughput

0.249

Low

732031

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low

732048

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024