Protein: IXR1
Intrastrand cross-link recognition protein (Structure-specific recognition protein) (SSRP)

Gene: IXR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 138
UniProt ID: P33417

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0001046 - core promoter sequence-specific DNA binding
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

490782

HSP71
Heat shock protein SSA1

5

12

Small-scale

0.699

High

493578

HSP72
Heat shock protein SSA2

3

12

Small-scale

0.624

High

510778

SSB1
Ribosome-associated molecular chaperone SSB1

3

13

Small-scale

0.624

High

705870

IXR1
Intrastrand cross-link recognition protein

1

16

Small-scale

0.621

High

705915

SMT3
Ubiquitin-like protein SMT3

2

11

High-throughput

0.600

High

705905

ABF2
ARS-binding factor 2, mitochondrial

1

20

High-throughput

0.575

High

406930

RS3
Small ribosomal subunit protein uS3

2

3

Small-scale

0.571

High

640894

RL5
Large ribosomal subunit protein uL18

2

3

Small-scale

0.571

High

705902

ACT
Actin

2

6

Small-scale

0.571

High

334653

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

Small-scale

0.552

High

480016

RS6A
Small ribosomal subunit protein eS6A

2

4

Small-scale

0.533

High

705880

RS20
Small ribosomal subunit protein uS10

2

4

Small-scale

0.533

High

333747

ADH1
Alcohol dehydrogenase 1

2

1

Small-scale

0.521

High

340093

KPYK1
Pyruvate kinase 1

2

2

Small-scale

0.521

High

367915

EF1A
Elongation factor 1-alpha

2

4

Small-scale

0.521

High

399396

RLA0
Large ribosomal subunit protein uL10

2

6

Small-scale

0.521

High

700315

RSSA1
Small ribosomal subunit protein uS2A

2

9

High-throughput

0.521

High

705892

MPG1
Mannose-1-phosphate guanyltransferase

2

3

Small-scale

0.521

High

705895

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

4

Small-scale

0.481

High

705917

CMR1
DNA damage-binding protein CMR1

1

20

High-throughput

0.481

High

366057

HSP82
ATP-dependent molecular chaperone HSP82

1

5

Small-scale

0.479

High

376710

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

3

Small-scale

0.479

High

449993

HSP73
Heat shock protein SSA3

1

12

Small-scale

0.479

High

498867

RL4A
Large ribosomal subunit protein uL4A

1

4

Small-scale

0.479

High

540554

CYPH
Peptidyl-prolyl cis-trans isomerase

1

5

Small-scale

0.479

High

557979

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.479

High

605325

HSP74
Heat shock protein SSA4

1

12

Small-scale

0.479

High

705874

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

705897

RL4B
Large ribosomal subunit protein uL4B

1

4

Small-scale

0.479

High

705901

RL15B
Large ribosomal subunit protein eL15B

1

2

Small-scale

0.479

High

705913

SCC1
Sister chromatid cohesion protein 1

1

3

High-throughput

0.479

High

705885

SAP1
Protein SAP1

1

3

High-throughput

0.464

High

410966

PDC1
Pyruvate decarboxylase isozyme 1

1

0

Small-scale

0.458

High

554613

HSP26
Heat shock protein 26

1

0

Small-scale

0.458

High

705903

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

1

0

Small-scale

0.458

High

355430

H2B1
Histone H2B.1

1

20

High-throughput

0.445

High

356373

H4
Histone H4

1

13

High-throughput

0.445

High

375596

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

8

High-throughput

0.445

High

392374

H2A2
Histone H2A.2

1

20

High-throughput

0.445

High

560618

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.445

High

606608

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

8

High-throughput

0.445

High

609068

SIN3
Transcriptional regulatory protein SIN3

1

3

High-throughput

0.445

High

675927

XPO1
Exportin-1

1

8

High-throughput

0.445

High

687679

BTAF1
TATA-binding protein-associated factor MOT1

1

20

High-throughput

0.445

High

696189

STH1
Nuclear protein STH1/NPS1

1

20

High-throughput

0.445

High

701163

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

2

High-throughput

0.445

High

704818

TFC4
Transcription factor tau 131 kDa subunit

1

4

High-throughput

0.445

High

705877

TAF5
Transcription initiation factor TFIID subunit 5

1

20

High-throughput

0.445

High

705878

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

20

High-throughput

0.445

High

705882

TRA1
Transcription-associated protein 1

1

4

High-throughput

0.445

High

705886

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

705893

RSC8
Chromatin structure-remodeling complex protein RSC8

1

13

High-throughput

0.445

High

705898

ITC1
Imitation switch two complex protein 1

1

4

High-throughput

0.445

High

705899

RSC1
Chromatin structure-remodeling complex subunit RSC1

1

20

High-throughput

0.445

High

705907

RUVB1
RuvB-like protein 1

1

9

High-throughput

0.445

High

705909

ARP9
Actin-like protein ARP9

1

11

High-throughput

0.445

High

705911

RSC3
Chromatin structure-remodeling complex protein RSC3

1

3

High-throughput

0.445

High

705912

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

20

High-throughput

0.445

High

705916

RUVB2
RuvB-like protein 2

1

9

High-throughput

0.445

High

334912

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

Small-scale

0.437

High

341982

ATPB
ATP synthase subunit beta, mitochondrial

1

8

Small-scale

0.437

High

342696

ENO1
Enolase 1

1

3

Small-scale

0.437

High

342899

ENO2
Enolase 2

1

3

Small-scale

0.437

High

343577

PMG1
Phosphoglycerate mutase 1

1

4

Small-scale

0.437

High

357482

RLA4
Large ribosomal subunit protein P2B

1

4

Small-scale

0.437

High

383049

RL25
Large ribosomal subunit protein uL23

1

3

Small-scale

0.437

High

389881

VDAC1
Mitochondrial outer membrane protein porin 1

1

2

Small-scale

0.437

High

393544

PMA1
Plasma membrane ATPase 1

1

4

Small-scale

0.437

High

399738

RLA1
Large ribosomal subunit protein P1A

1

1

Small-scale

0.437

High

399864

RLA2
Large ribosomal subunit protein P2A

1

4

Small-scale

0.437

High

404540

RL7A
Large ribosomal subunit protein uL30A

1

5

Small-scale

0.437

High

406315

RL15A
Large ribosomal subunit protein eL15A

1

2

Small-scale

0.437

High

410493

CYSD
Homocysteine/cysteine synthase

1

1

Small-scale

0.437

High

413413

RS14A
Small ribosomal subunit protein uS11A

1

4

High-throughput

0.437

High

419679

RHO1
GTP-binding protein RHO1

1

11

Small-scale

0.437

High

423816

ATPA
ATP synthase subunit alpha, mitochondrial

1

8

Small-scale

0.437

High

425114

LEUC
3-isopropylmalate dehydratase

1

1

Small-scale

0.437

High

470962

RS22A
Small ribosomal subunit protein uS8A

1

4

Small-scale

0.437

High

471758

RL27A
Large ribosomal subunit protein eL27A

1

4

Small-scale

0.437

High

471886

RL27B
Large ribosomal subunit protein eL27B

1

4

Small-scale

0.437

High

478864

RL20B
Large ribosomal subunit protein eL20B

1

2

Small-scale

0.437

High

480580

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.437

High

481135

RL1A
Large ribosomal subunit protein uL1A

1

5

Small-scale

0.437

High

482177

RS18A
Small ribosomal subunit protein uS13A

1

4

High-throughput

0.437

High

482690

RL19B
Large ribosomal subunit protein eL19

1

2

Small-scale

0.437

High

523260

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

2

High-throughput

0.437

High

534934

RL3
Large ribosomal subunit protein uL3

1

4

Small-scale

0.437

High

543477

HSC82
ATP-dependent molecular chaperone HSC82

1

5

Small-scale

0.437

High

581280

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

Small-scale

0.437

High

586124

PMA2
Plasma membrane ATPase 2

1

4

Small-scale

0.437

High

631777

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.437

High

644857

RS5
Small ribosomal subunit protein uS7

1

4

Small-scale

0.437

High

645349

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

687337

EF2
Elongation factor 2

1

6

Small-scale

0.437

High

705871

RS3A1
Small ribosomal subunit protein eS1A

1

5

High-throughput

0.437

High

705873

TSA1
Peroxiredoxin TSA1

1

6

Small-scale

0.437

High

705883

HXT6
High-affinity hexose transporter HXT6

1

1

Small-scale

0.437

High

705884

HXT7
High-affinity hexose transporter HXT7

1

1

Small-scale

0.437

High

705887

RL13B
Large ribosomal subunit protein eL13B

1

2

Small-scale

0.437

High

705888

6P21
6-phosphofructo-2-kinase 1

1

5

Small-scale

0.437

High

705891

RL10
Large ribosomal subunit protein uL16

1

4

Small-scale

0.437

High

705894

RSSA2
Small ribosomal subunit protein uS2B

1

9

Small-scale

0.437

High

705896

RS12
Small ribosomal subunit protein eS12

1

3

Small-scale

0.437

High

705900

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

Small-scale

0.437

High

705908

RTN1
Reticulon-like protein 1

1

2

Small-scale

0.437

High

705914

RL7B
Large ribosomal subunit protein uL30B

1

5

Small-scale

0.437

High

705918

RS21B
Small ribosomal subunit protein eS21B

1

1

Small-scale

0.437

High

705919

RS22B
Small ribosomal subunit protein uS8B

1

4

Small-scale

0.437

High

454267

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

705881

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.426

High

705904

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

410102

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.407

High

424441

PYR1
Multifunctional protein URA2

1

5

High-throughput

0.407

High

555945

VATB
V-type proton ATPase subunit B

1

8

High-throughput

0.407

High

657047

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

3

High-throughput

0.407

High

705872

GCN1
eIF-2-alpha kinase activator GCN1

1

6

High-throughput

0.407

High

705879

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.407

High

705889

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

3

High-throughput

0.407

High

705910

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.407

High

336135

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

0

Small-scale

0.249

Low

340650

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.249

Low

343374

TPIS
Triosephosphate isomerase

1

0

Small-scale

0.249

Low

389263

HXKA
Hexokinase-1

1

0

Small-scale

0.249

Low

404324

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

Small-scale

0.249

Low

421498

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

Small-scale

0.249

Low

501283

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.249

Low

537389

ALF
Fructose-bisphosphate aldolase

1

0

Small-scale

0.249

Low

583212

METK2
S-adenosylmethionine synthase 2

1

0

Small-scale

0.249

Low

635226

HSP30
30 kDa heat shock protein

1

0

Small-scale

0.249

Low

690579

EF1B
Elongation factor 1-beta

1

0

Small-scale

0.249

Low

693191

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

Small-scale

0.249

Low

705875

PET10
Protein PET10

1

0

Small-scale

0.249

Low

705876

AHP1
Peroxiredoxin AHP1

1

0

Small-scale

0.249

Low

705890

FET4
Low-affinity Fe(2+) transport protein

1

0

Small-scale

0.249

Low

705906

MSC1
Meiotic sister chromatid recombination protein 1

1

0

Small-scale

0.249

Low

360825

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

634996

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024