Protein: KAE1
tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (Kinase-associated endopeptidase 1) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1) (tRNA threonylcarbamoyladenosine biosynthesis protein KAE1)

Gene: KAE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 81
UniProt ID: P36132

Gene Ontology (top 5):
GO:0000408 - EKC/KEOPS complex
GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0000785 - chromatin
GO:0002949 - tRNA threonylcarbamoyladenosine modification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733477

PCC1
EKC/KEOPS complex subunit PCC1

3

0

Small-scale

0.796

High

733458

BUD32
EKC/KEOPS complex subunit BUD32

9

1

Small-scale

0.759

High

733463

CG121
EKC/KEOPS complex subunit CGI121

6

1

Small-scale

0.735

High

733448

GON7
EKC/KEOPS complex subunit GON7

7

0

Small-scale

0.717

High

733424

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

3

Small-scale

0.575

High

733439

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

510939

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.536

High

733430

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.536

High

733437

VHR2
Transcription factor VHR2

1

0

High-throughput

0.493

High

688683

TREA
Cytosolic neutral trehalase

1

1

High-throughput

0.479

High

715258

TREB
Probable trehalase

1

1

High-throughput

0.479

High

733440

TBP6
Probable 26S proteasome subunit YTA6

1

1

High-throughput

0.479

High

733452

CTF18
Chromosome transmission fidelity protein 18

1

1

High-throughput

0.479

High

733456

CUL3
Cullin-3

1

1

High-throughput

0.479

High

733461

ARP5
Actin-related protein 5

1

2

High-throughput

0.479

High

419470

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

539894

RAD4
DNA repair protein RAD4

1

0

High-throughput

0.458

High

558009

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

604257

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

634238

GID7
Glucose-induced degradation protein 7

1

0

High-throughput

0.458

High

690363

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

0

High-throughput

0.458

High

693668

SUA5
Threonylcarbamoyl-AMP synthase

1

0

High-throughput

0.458

High

699152

RAD5
DNA repair protein RAD5

1

0

High-throughput

0.458

High

733425

ERT1
Transcription activator of gluconeogenesis ERT1

1

0

High-throughput

0.458

High

733426

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.458

High

733427

TTL
Probable tubulin--tyrosine ligase PBY1

1

0

High-throughput

0.458

High

733428

YBY8
Uncharacterized protein YBR138C

1

0

High-throughput

0.458

High

733431

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.458

High

733432

MSS4
Phosphatidylinositol 4-phosphate 5-kinase MSS4

1

0

High-throughput

0.458

High

733435

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

0

High-throughput

0.458

High

733436

PCL6
PHO85 cyclin-6

1

0

High-throughput

0.458

High

733441

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.458

High

733442

ATG3
Autophagy-related protein 3

1

0

High-throughput

0.458

High

733444

MAD1
Spindle assembly checkpoint component MAD1

1

0

High-throughput

0.458

High

733445

THI6
Thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase

1

0

High-throughput

0.458

High

733446

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.458

High

733447

REF2
RNA end formation protein 2

1

0

High-throughput

0.458

High

733449

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.458

High

733450

TTI2
TEL2-interacting protein 2

1

0

High-throughput

0.458

High

733451

TEA1
TY1 enhancer activator

1

0

High-throughput

0.458

High

733453

LIF1
Ligase-interacting factor 1

1

0

High-throughput

0.458

High

733454

SDS23
Protein SDS23

1

0

High-throughput

0.458

High

733457

ATF2
Alcohol O-acetyltransferase 2

1

0

High-throughput

0.458

High

733459

DSL1
Protein transport protein DSL1

1

0

High-throughput

0.458

High

733464

EKI1
Ethanolamine kinase

1

0

High-throughput

0.458

High

733466

LCD1
DNA damage checkpoint protein LCD1

1

0

High-throughput

0.458

High

733469

MFG1
Morphogenetic regulator of filamentous growth protein 1

1

0

High-throughput

0.458

High

733473

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

733474

YL054
Uncharacterized transcriptional regulatory protein YLL054C

1

0

High-throughput

0.458

High

733475

NTO1
NuA3 HAT complex component NTO1

1

0

High-throughput

0.458

High

733476

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.458

High

733478

SEY1
Protein SEY1

1

0

High-throughput

0.458

High

366125

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

478095

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

490911

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

493695

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

543556

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.445

High

633136

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

680621

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

694493

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

705051

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

733434

XDJ1
DnaJ protein homolog XDJ1

1

4

High-throughput

0.445

High

733460

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.445

High

733443

CHS6
Chitin biosynthesis protein CHS6

1

1

High-throughput

0.437

High

733472

BUD7
Bud site selection protein 7

1

1

High-throughput

0.437

High

333763

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

342702

ENO1
Enolase 1

1

0

High-throughput

0.426

High

733429

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.426

High

577533

ARGD
Acetylornithine aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

629552

CDC10
Cell division control protein 10

1

0

High-throughput

0.249

Low

731648

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.249

Low

733438

PEA2
Protein PEA2

1

0

High-throughput

0.249

Low

733455

SCW11
Probable family 17 glucosidase SCW11

1

0

High-throughput

0.249

Low

733462

EAR1
Protein EAR1

1

0

High-throughput

0.249

Low

733465

GPI17
GPI transamidase component GPI17

1

0

High-throughput

0.249

Low

733467

SPH1
Protein SPH1

1

0

High-throughput

0.249

Low

733468

MRX9
MIOREX complex component 9

1

0

High-throughput

0.249

Low

733470

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.249

Low

733471

SDHF2
Succinate dehydrogenase assembly factor 2, mitochondrial

1

0

High-throughput

0.249

Low

733433

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024