Protein: HCH1
Hsp90 co-chaperone HCH1 (High-copy Hsp90 suppressor protein 1)

Gene: HCH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 57
UniProt ID: P53834

Gene Ontology (top 5):
GO:0001671 - ATPase activator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366685

HSP82
ATP-dependent molecular chaperone HSP82

7

11

Small-scale

0.952

High

544183

HSC82
ATP-dependent molecular chaperone HSC82

6

11

Small-scale

0.934

High

865212

AHA1
Hsp90 co-chaperone AHA1

3

1

Small-scale

0.814

High

797506

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

756547

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

High-throughput

0.552

High

494610

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

512230

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

695229

HSP7F
Heat shock protein homolog SSE1

2

7

High-throughput

0.552

High

728295

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.518

High

742729

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.518

High

864569

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

865206

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

741341

STT4
Phosphatidylinositol 4-kinase STT4

1

0

High-throughput

0.493

High

768395

GPP2
Glycerol-1-phosphate phosphohydrolase 2

1

0

High-throughput

0.493

High

865209

RUB1
NEDD8-like protein RUB1

1

0

High-throughput

0.493

High

865208

ULP1
Ubiquitin-like-specific protease 1

1

2

High-throughput

0.481

High

865211

RIO1
Serine/threonine-protein kinase RIO1

1

1

Small-scale

0.481

High

358190

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

407221

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

426078

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

471180

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

480235

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

632010

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

662938

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

700549

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

752586

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

820094

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

865207

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

865210

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

694167

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

774892

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.458

High

340229

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

342078

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.445

High

368283

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

454420

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.445

High

492019

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

540129

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.445

High

556208

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

560755

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.445

High

562265

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.445

High

687444

EF2
Elongation factor 2

1

2

High-throughput

0.445

High

693339

RPN2
26S proteasome regulatory subunit RPN2

1

3

High-throughput

0.445

High

705494

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

752951

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.445

High

753901

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.445

High

766145

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.445

High

769084

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

785141

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

333872

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

411052

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.426

High

730659

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.426

High

746587

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.426

High

561038

EF3A
Elongation factor 3A

1

3

High-throughput

0.407

High

566636

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.407

High

784399

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.407

High

796922

GCN20
Protein GCN20

1

2

High-throughput

0.407

High

420317

CALM
Calmodulin

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024