Protein: UFD4
Ubiquitin fusion degradation protein 4 (UB fusion protein 4) (EC 2.3.2.-) (HECT-type E3 ubiquitin transferase UFD4) (EC 2.3.2.26)

Gene: UFD4
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: P33202

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549801

UBC4
Ubiquitin-conjugating enzyme E2 4

5

20

Small-scale

0.924

High

477197

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

4

20

Small-scale

0.885

High

703170

PRS8
26S proteasome regulatory subunit 8 homolog

3

20

Small-scale

0.681

High

703148

UFD4
Ubiquitin fusion degradation protein 4

1

15

Small-scale

0.621

High

477612

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

20

High-throughput

0.618

High

703171

UBC7
Ubiquitin-conjugating enzyme E2 7

1

20

Small-scale

0.618

High

640306

MGMT
Methylated-DNA--protein-cysteine methyltransferase

2

0

Small-scale

0.612

High

587301

UBR1
E3 ubiquitin-protein ligase UBR1

2

0

Small-scale

0.606

High

703160

TCPQ
T-complex protein 1 subunit theta

2

15

High-throughput

0.601

High

703149

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.571

High

493555

HSP72
Heat shock protein SSA2

2

13

High-throughput

0.552

High

510749

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.552

High

581278

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

12

High-throughput

0.541

High

334461

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

3

High-throughput

0.536

High

360819

TBB
Tubulin beta chain

1

13

High-throughput

0.536

High

367905

EF1A
Elongation factor 1-alpha

1

8

High-throughput

0.536

High

424431

PYR1
Multifunctional protein URA2

1

10

High-throughput

0.536

High

454264

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.536

High

485684

IF4A
ATP-dependent RNA helicase eIF4A

1

20

High-throughput

0.536

High

703152

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.536

High

703159

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

703162

FMP48
Probable serine/threonine-protein kinase FMP48

1

15

High-throughput

0.536

High

703184

AHA1
Hsp90 co-chaperone AHA1

1

1

High-throughput

0.536

High

584146

ACON
Aconitate hydratase, mitochondrial

1

3

High-throughput

0.515

High

703153

RPN1
26S proteasome regulatory subunit RPN1

1

11

Small-scale

0.515

High

634994

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.513

High

692275

PRP19
Pre-mRNA-processing factor 19

1

16

High-throughput

0.508

High

703163

PRS10
26S proteasome subunit RPT4

1

20

Small-scale

0.501

High

703165

UFD2
E4 ubiquitin-protein ligase UFD2

1

2

Small-scale

0.501

High

703178

TPO1
Polyamine transporter 1

1

2

High-throughput

0.494

High

700305

RSSA1
Small ribosomal subunit protein uS2A

1

9

High-throughput

0.489

High

703155

TEM1
Protein TEM1

1

4

High-throughput

0.489

High

703168

AP1M1
AP-1 complex subunit mu-1-I

1

3

High-throughput

0.489

High

703167

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

3

High-throughput

0.481

High

402920

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

10

Small-scale

0.479

High

566151

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

661765

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

693970

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

11

High-throughput

0.479

High

700817

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

703151

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

703158

PSA4
Proteasome subunit alpha type-4

1

20

Small-scale

0.479

High

703166

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

20

Small-scale

0.479

High

703172

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

703173

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

703177

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

703180

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

703181

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

703156

ATC3
Phospholipid-transporting ATPase DRS2

1

4

High-throughput

0.470

High

703169

KIN4
Serine/threonine-protein kinase KIN4

1

15

High-throughput

0.470

High

688173

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

703175

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

399391

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.445

High

427218

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.445

High

490757

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

543458

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.445

High

554609

HSP26
Heat shock protein 26

1

9

High-throughput

0.445

High

555936

VATB
V-type proton ATPase subunit B

1

10

High-throughput

0.445

High

627869

SIS1
Protein SIS1

1

13

High-throughput

0.445

High

633081

MAS5
Mitochondrial protein import protein MAS5

1

10

High-throughput

0.445

High

694383

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

703150

MDJ1
DnaJ homolog 1, mitochondrial

1

11

High-throughput

0.445

High

703154

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

703157

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

703174

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

17

High-throughput

0.445

High

703182

HSP42
Heat shock protein 42

1

9

High-throughput

0.445

High

638697

SPB4
ATP-dependent rRNA helicase SPB4

1

20

High-throughput

0.437

High

703176

YD073
UPF0592 protein YDL073W

1

1

High-throughput

0.437

High

703164

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

703179

AB140
tRNA(Thr)

1

0

High-throughput

0.426

High

703183

JID1
J domain-containing protein 1

1

0

High-throughput

0.426

High

576223

ERD2
ER lumen protein-retaining receptor

1

1

High-throughput

0.407

High

703161

HLJ1
Protein HLJ1

1

11

High-throughput

0.407

High

690415

HYM1
Protein HYM1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024