Protein: TOF1
Topoisomerase 1-associated factor 1

Gene: TOF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P53840

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006260 - DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

865232

CSM3
Chromosome segregation in meiosis protein 3

11

0

Small-scale

0.726

High

667876

MCM5
Minichromosome maintenance protein 5

5

8

Small-scale

0.709

High

634889

MRC1
Mediator of replication checkpoint protein 1

5

0

Small-scale

0.685

High

865234

CDC45
Cell division control protein 45

4

1

Small-scale

0.683

High

858997

MCM6
DNA replication licensing factor MCM6

3

9

Small-scale

0.656

High

667609

MCM2
DNA replication licensing factor MCM2

3

8

Small-scale

0.640

High

675541

MCM4
DNA replication licensing factor MCM4

3

9

Small-scale

0.640

High

865229

SLD5
DNA replication complex GINS protein SLD5

3

1

Small-scale

0.633

High

622180

MCM3
DNA replication licensing factor MCM3

2

9

Small-scale

0.611

High

388117

TOP1
DNA topoisomerase 1

2

0

Small-scale

0.593

High

692861

SPT16
FACT complex subunit SPT16

2

0

Small-scale

0.569

High

700791

SMC1
Structural maintenance of chromosomes protein 1

1

1

Small-scale

0.561

High

810764

SMC3
Structural maintenance of chromosomes protein 3

1

1

Small-scale

0.561

High

865235

SCC1
Sister chromatid cohesion protein 1

1

0

Small-scale

0.537

High

512232

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.513

High

608750

CHL1
ATP-dependent DNA helicase CHL1

1

1

Small-scale

0.501

High

865231

POB3
FACT complex subunit POB3

1

1

Small-scale

0.501

High

334513

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.493

High

756206

RT107
Regulator of Ty1 transposition protein 107

1

0

Small-scale

0.486

High

775342

SCC3
Cohesin subunit SCC3

1

0

Small-scale

0.480

High

526854

DPOLA
DNA polymerase alpha catalytic subunit A

1

2

Small-scale

0.479

High

687546

DBF4
DDK kinase regulatory subunit DBF4

1

1

Small-scale

0.479

High

744784

MCM7
DNA replication licensing factor MCM7

1

7

High-throughput

0.479

High

756057

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.460

High

662940

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

664976

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

743620

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

865230

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

865233

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

865236

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

865238

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.458

High

492022

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494613

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

695230

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

865227

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

544184

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

633448

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

754597

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

865228

NU100
Nucleoporin NUP100/NSP100

2

0

Small-scale

0.305

High

865237

ERV2
FAD-linked sulfhydryl oxidase ERV2

1

0

High-throughput

0.269

Low

750991

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.249

Low

705495

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

766146

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low

810094

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024