Protein: MAOM
NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38)

Gene: MAOM, MAE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 124
UniProt ID: P36013

Gene Ontology (top 5):
GO:0004470 - malic enzyme activity
GO:0004471 - malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

478085

HSP77
Import motor subunit, mitochondrial

2

3

High-throughput

0.584

High

731027

RUVB2
RuvB-like protein 2

2

1

High-throughput

0.558

High

340107

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.536

High

440015

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.536

High

454277

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.536

High

454592

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.536

High

687351

EF2
Elongation factor 2

1

1

High-throughput

0.536

High

707835

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.536

High

730987

SMK1
Sporulation-specific mitogen-activated protein kinase SMK1

1

1

High-throughput

0.536

High

731004

ACAC
Acetyl-CoA carboxylase

1

2

High-throughput

0.536

High

731005

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

731022

MDN1
Midasin

1

1

High-throughput

0.536

High

343113

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.513

High

360837

TBB
Tubulin beta chain

1

0

High-throughput

0.513

High

367943

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.513

High

388968

SYTC
Threonine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

421618

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.513

High

424462

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.513

High

440879

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.513

High

450299

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

498495

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.513

High

534734

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

540074

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.513

High

594311

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.513

High

657225

URA7
CTP synthase 1

1

0

High-throughput

0.513

High

700333

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.513

High

730975

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.513

High

730981

GEA2
ARF guanine-nucleotide exchange factor 2

1

0

High-throughput

0.513

High

730984

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.513

High

730992

SA155
SIT4-associating protein SAP155

1

0

High-throughput

0.513

High

731000

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

731012

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

731017

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.513

High

731020

LKHA4
Leucine aminopeptidase 2

1

0

High-throughput

0.493

High

566566

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.489

High

675951

XPO1
Exportin-1

1

1

High-throughput

0.489

High

687925

IMB3
Importin subunit beta-3

1

1

High-throughput

0.489

High

693282

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.489

High

730973

ECM29
Proteasome component ECM29

1

2

High-throughput

0.489

High

730974

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.489

High

730997

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.489

High

730998

MSN5
Protein MSN5

1

1

High-throughput

0.489

High

470984

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

606616

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

680610

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

698766

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

705030

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

730999

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.479

High

731002

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

357992

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

406954

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

425874

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

427229

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

480595

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

481137

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.458

High

482193

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

543532

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

612939

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

627914

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

650215

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.458

High

661888

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

689473

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

692491

ZUO1
Zuotin

1

0

Small-scale

0.458

High

699844

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

730969

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

730980

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

730985

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

730986

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

730991

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

730994

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

731006

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

731010

ESP1
Separin

1

0

High-throughput

0.458

High

731016

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

731021

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

731023

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

730983

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

730996

PHB2
Prohibitin-2

1

1

High-throughput

0.445

High

731029

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.445

High

355445

H2B1
Histone H2B.1

1

1

High-throughput

0.437

High

355863

H2B2
Histone H2B.2

1

1

High-throughput

0.437

High

731015

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

334662

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

382730

RL24A
Large ribosomal subunit protein eL24A

1

0

High-throughput

0.426

High

501353

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.426

High

613672

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.426

High

644864

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.426

High

691460

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.426

High

730970

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.426

High

730979

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.426

High

730993

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

730982

IMB4
Importin subunit beta-4

1

1

High-throughput

0.407

High

731009

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.407

High

356402

H4
Histone H4

2

0

High-throughput

0.318

High

688966

VA0D
V-type proton ATPase subunit d

2

0

High-throughput

0.293

High

730971

KPR3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.279

Low

730972

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.279

Low

730977

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.279

Low

730978

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.279

Low

730988

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

730989

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.279

Low

730990

GCN20
Protein GCN20

1

0

High-throughput

0.279

Low

731007

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.279

Low

731011

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.279

Low

731013

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.279

Low

524258

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

633849

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

688193

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

701374

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

730995

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

731003

H3
Histone H3

1

0

High-throughput

0.249

Low

731008

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.249

Low

731014

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

731018

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

731024

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

731026

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.249

Low

731028

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.249

Low

410109

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.232

Low

519926

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

555969

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

561232

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.232

Low

730976

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

731001

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

731019

BRX1
Ribosome biogenesis protein BRX1

1

0

High-throughput

0.232

Low

731025

ARP7
Actin-related protein 7

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024