Protein: PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Phosphatase two C protein 5) (Protein phosphatase 2C homolog 5) (PP2C-5) (Protein phosphatase of PDH protein 1) (Pyruvate dehydrogenase complex phosphatase 1) (PDC phosphatase 1)

Gene: PDP1, PTC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: Q12511

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004741 - [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0019909 - [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961950

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

11

High-throughput

0.621

High

1015703

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

1

High-throughput

0.618

High

423493

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

2

0

High-throughput

0.585

High

367138

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.555

High

495388

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.536

High

774973

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.513

High

627715

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.489

High

393634

PMA1
Plasma membrane ATPase 1

1

2

High-throughput

0.479

High

478635

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.479

High

686237

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

698224

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

3

High-throughput

0.479

High

732062

MCR1
NADH-cytochrome b5 reductase 2

1

1

High-throughput

0.479

High

746103

MOH1
Protein yippee-like MOH1

1

1

High-throughput

0.479

High

755080

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

3

High-throughput

0.479

High

757244

CYC2
Cytochrome c mitochondrial import factor CYC2

1

1

High-throughput

0.479

High

770309

CCS1
Superoxide dismutase 1 copper chaperone

1

2

High-throughput

0.479

High

770500

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

1

High-throughput

0.479

High

778540

PHB1
Prohibitin-1

1

1

High-throughput

0.479

High

837198

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

991479

NDH2
External NADH-ubiquinone oxidoreductase 2, mitochondrial

1

1

High-throughput

0.479

High

993230

FMP25
Protein FMP25, mitochondrial

1

1

High-throughput

0.479

High

335975

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

357394

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

421523

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

439736

NUC1
Mitochondrial nuclease

1

0

High-throughput

0.458

High

585245

COX11
Cytochrome c oxidase assembly protein COX11, mitochondrial

1

0

High-throughput

0.458

High

604288

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

619774

TOM40
Mitochondrial import receptor subunit TOM40

1

0

High-throughput

0.458

High

634301

MGR1
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1

1

0

High-throughput

0.458

High

668100

TRXB1
Thioredoxin reductase 1

1

0

High-throughput

0.458

High

686945

MGM1
Dynamin-like GTPase MGM1, mitochondrial

1

0

High-throughput

0.458

High

699653

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

0

High-throughput

0.458

High

716058

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

0

High-throughput

0.458

High

734095

OMA1
Mitochondrial metalloendopeptidase OMA1

1

0

High-throughput

0.458

High

743488

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

0

High-throughput

0.458

High

743494

SCO2
Protein SCO2, mitochondrial

1

0

High-throughput

0.458

High

759053

PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial

1

0

High-throughput

0.458

High

764278

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.458

High

766625

FMP52
Protein FMP52, mitochondrial

1

0

High-throughput

0.458

High

772746

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.458

High

810860

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

High-throughput

0.458

High

864346

RCF2
Respiratory supercomplex factor 2, mitochondrial

1

0

High-throughput

0.458

High

953325

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

0

High-throughput

0.458

High

972452

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.458

High

973426

FMP30
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial

1

0

High-throughput

0.458

High

988544

OMS1
Methyltransferase OMS1, mitochondrial

1

0

High-throughput

0.458

High

1015237

MDM32
Mitochondrial distribution and morphology protein 32

1

0

High-throughput

0.458

High

544649

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.445

High

481091

RL23B
Large ribosomal subunit protein uL14B

1

1

High-throughput

0.437

High

692985

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

730961

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.437

High

847982

GCH1
GTP cyclohydrolase 1

1

1

High-throughput

0.437

High

979404

HNT1
Adenosine 5'-monophosphoramidase HNT1

1

1

High-throughput

0.437

High

979871

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

492941

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.407

High

513328

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

695877

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.407

High

773802

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.407

High

752090

KPR3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.279

Low

772705

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.279

Low

1015704

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.279

Low

739506

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.269

Low

499127

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

566688

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.249

Low

752743

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

755886

LSM12
Protein LSM12

1

0

High-throughput

0.249

Low

757380

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.249

Low

757977

CSK2C
Casein kinase II subunit beta'

1

0

High-throughput

0.249

Low

770176

PIG2
GSY2-interacting protein PIG2

1

0

High-throughput

0.249

Low

770389

SIP5
Protein SIP5

1

0

High-throughput

0.249

Low

775914

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

807621

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.249

Low

861592

SCW4
Probable family 17 glucosidase SCW4

1

0

High-throughput

0.249

Low

872769

ERG5
C-22 sterol desaturase ERG5

1

0

High-throughput

0.249

Low

986298

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

987851

CDD
Cytidine deaminase

1

0

High-throughput

0.249

Low

991523

KAR
NADPH-dependent alpha-keto amide reductase

1

0

High-throughput

0.249

Low

628625

SIS1
Protein SIS1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024