Protein: MDHM
Malate dehydrogenase, mitochondrial (EC 1.1.1.37)

Gene: MDHM, MDH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 113
UniProt ID: P17505

Gene Ontology (top 5):
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006099 - tricarboxylic acid cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567946

MDHP
Malate dehydrogenase, peroxisomal

2

13

Small-scale

0.754

High

477867

HSP77
Import motor subunit, mitochondrial

4

9

Small-scale

0.672

High

567919

ACON
Aconitate hydratase, mitochondrial

3

3

Small-scale

0.640

High

567962

LONM
Lon protease homolog, mitochondrial

3

10

Small-scale

0.640

High

567984

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

3

2

Small-scale

0.640

High

567957

HSP78
Heat shock protein 78, mitochondrial

3

1

Small-scale

0.633

High

342341

CISY1
Citrate synthase, mitochondrial

2

5

Small-scale

0.624

High

567925

MDHC
Malate dehydrogenase, cytoplasmic

1

14

Small-scale

0.618

High

427170

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

2

1

Small-scale

0.584

High

558552

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

2

4

High-throughput

0.584

High

567921

HSP60
Heat shock protein 60, mitochondrial

2

3

Small-scale

0.584

High

567935

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

2

2

High-throughput

0.584

High

567941

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

2

4

Small-scale

0.584

High

567944

HS104
Heat shock protein 104

2

2

Small-scale

0.584

High

567955

PREP
Presequence protease, mitochondrial

2

3

Small-scale

0.584

High

443968

CISY2
Citrate synthase, peroxisomal

1

5

Small-scale

0.561

High

410749

ILV5
Ketol-acid reductoisomerase, mitochondrial

2

0

Small-scale

0.559

High

423572

ADH3
Alcohol dehydrogenase 3, mitochondrial

2

0

Small-scale

0.559

High

567961

MIC60
MICOS complex subunit MIC60

2

0

Small-scale

0.559

High

567977

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

567934

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

2

High-throughput

0.536

High

567936

CDC20
APC/C activator protein CDC20

1

3

High-throughput

0.536

High

567948

APE2
Aminopeptidase 2, mitochondrial

1

1

High-throughput

0.536

High

567951

PP12
Serine/threonine-protein phosphatase PP1-2

1

3

High-throughput

0.536

High

567952

FIMB
Fimbrin

1

1

High-throughput

0.536

High

567953

RAD54
DNA repair and recombination protein RAD54

1

2

High-throughput

0.536

High

567965

ATR
Serine/threonine-protein kinase MEC1

1

2

High-throughput

0.536

High

567969

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.536

High

567978

RAD26
DNA repair and recombination protein RAD26

1

3

High-throughput

0.536

High

567990

RBG2
Ribosome-interacting GTPase 2

1

3

High-throughput

0.536

High

568003

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

7

High-throughput

0.536

High

341644

ARGI
Arginase

1

0

High-throughput

0.513

High

567927

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.513

High

567943

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

567959

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.513

High

567979

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.513

High

568001

BUD20
Bud site selection protein 20

1

0

High-throughput

0.513

High

523237

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

1

Small-scale

0.501

High

493132

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.500

High

429618

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.489

High

567920

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.489

High

485448

SSBP1
Single-stranded nucleic acid-binding protein

1

0

Small-scale

0.480

High

341909

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.479

High

365747

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

372798

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

4

Small-scale

0.479

High

411214

LEU1
2-isopropylmalate synthase

1

2

Small-scale

0.479

High

424169

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

4

Small-scale

0.479

High

452950

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

4

Small-scale

0.479

High

489665

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

567922

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

6

Small-scale

0.479

High

567923

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

1

Small-scale

0.479

High

567924

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.479

High

567926

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

567929

AIM17
Probable oxidoreductase AIM17

1

1

High-throughput

0.479

High

567937

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

3

High-throughput

0.479

High

567939

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

4

High-throughput

0.479

High

567949

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

2

High-throughput

0.479

High

567950

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.479

High

567954

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

567958

PRX1
Peroxiredoxin PRX1, mitochondrial

1

5

Small-scale

0.479

High

567963

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

2

High-throughput

0.479

High

567967

GRPE
GrpE protein homolog, mitochondrial

1

1

High-throughput

0.479

High

567972

FHP
Flavohemoprotein

1

1

Small-scale

0.479

High

567975

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

2

High-throughput

0.479

High

567982

ETFB
Probable electron transfer flavoprotein subunit beta

1

1

High-throughput

0.479

High

567987

LYS4
Homoaconitase, mitochondrial

1

3

High-throughput

0.479

High

567988

ALAM
Probable alanine aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

567989

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.479

High

567992

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

567993

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

4

Small-scale

0.479

High

567995

ATN2
Sodium/potassium exporting P-type ATPase 2

1

3

Small-scale

0.479

High

567996

CLU
Clustered mitochondria protein 1

1

1

Small-scale

0.479

High

567998

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

9

High-throughput

0.479

High

336194

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.458

High

373205

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

404297

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

Small-scale

0.458

High

567928

UBA1
Ubiquitin-activating enzyme E1 1

1

0

Small-scale

0.458

High

567932

PRTD
Saccharolysin

1

0

High-throughput

0.458

High

567933

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

567938

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.458

High

567940

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.458

High

567945

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

567947

BIOB
Biotin synthase, mitochondrial

1

0

Small-scale

0.458

High

567956

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.458

High

567960

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

567970

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

567971

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

567973

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

567976

AIM9
Altered inheritance of mitochondria protein 9, mitochondrial

1

0

High-throughput

0.458

High

567980

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

567983

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

Small-scale

0.458

High

567985

DLD2
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2

1

0

High-throughput

0.458

High

567986

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

567994

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

0

High-throughput

0.458

High

567997

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

568002

ETFD
Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.458

High

340006

KPYK1
Pyruvate kinase 1

1

2

High-throughput

0.445

High

510177

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

530127

ATN1
Sodium/potassium exporting P-type ATPase 1

1

3

Small-scale

0.437

High

567930

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

567931

BUD31
Pre-mRNA-splicing factor BUD31

1

1

Small-scale

0.437

High

567942

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

567964

HMT1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.437

High

567966

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

567999

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

568004

ATN5
Sodium/potassium exporting P-type ATPase 5

1

3

Small-scale

0.437

High

367706

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

567981

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

420464

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

High-throughput

0.279

Low

567974

GIP2
GLC7-interacting protein 2

1

0

High-throughput

0.279

Low

567991

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.279

Low

568000

YD306
F-box protein YDR306C

1

0

High-throughput

0.279

Low

567968

YGP1
Protein YGP1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024