Protein: TSA1
Peroxiredoxin TSA1 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 1) (cTPx 1) (Protector protein) (PRP) (Thiol-specific antioxidant protein 1) (Thioredoxin peroxidase type Ia) (TPx type Ia) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin TSA1)

Gene: TSA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 132
UniProt ID: P34760

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006111 - regulation of gluconeogenesis
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

713205

TSA1
Peroxiredoxin TSA1

11

14

Small-scale

0.975

High

611720

TRX2
Thioredoxin-2

5

20

Small-scale

0.930

High

606199

TRX1
Thioredoxin-1

4

20

Small-scale

0.886

High

713262

TSA2
Peroxiredoxin TSA2

3

14

High-throughput

0.854

High

713211

SRX1
Sulfiredoxin

2

5

Small-scale

0.768

High

694426

HSP7F
Heat shock protein homolog SSE1

3

10

High-throughput

0.662

High

627902

SIS1
Protein SIS1

3

1

High-throughput

0.640

High

713239

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

3

High-throughput

0.640

High

490822

HSP71
Heat shock protein SSA1

3

8

Small-scale

0.633

High

510825

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

Small-scale

0.595

High

713254

UBC7
Ubiquitin-conjugating enzyme E2 7

2

2

High-throughput

0.586

High

713231

SSB2
Ribosome-associated molecular chaperone SSB2

2

9

Small-scale

0.585

High

713233

MLP2
Protein MLP2

3

4

Small-scale

0.585

High

493616

HSP72
Heat shock protein SSA2

2

8

Small-scale

0.584

High

543502

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.584

High

713256

IMA1
Importin subunit alpha

2

1

Small-scale

0.576

High

340099

KPYK1
Pyruvate kinase 1

1

1

Small-scale

0.561

High

587838

AP1
AP-1-like transcription factor YAP1

1

0

Small-scale

0.554

High

713280

SMC6
Structural maintenance of chromosomes protein 6

2

2

High-throughput

0.543

High

713237

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.536

High

713246

MPA43
Protein MPA43

1

2

High-throughput

0.536

High

713247

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

713252

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

713259

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.536

High

713236

CRS5
Metallothionein-like protein CRS5

1

1

Small-scale

0.527

High

713271

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

0

Small-scale

0.513

High

350768

RAS1
Ras-like protein 1

1

2

High-throughput

0.508

High

696921

FRDS
Fumarate reductase 1

1

1

Small-scale

0.501

High

503071

ARF1
ADP-ribosylation factor 1

1

2

High-throughput

0.500

High

713210

VPS21
Vacuolar protein sorting-associated protein 21

1

3

High-throughput

0.500

High

713263

CAC2
Chromatin assembly factor 1 subunit p60

1

6

High-throughput

0.500

High

713207

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.489

High

713268

DPP3
Probable dipeptidyl peptidase 3

1

0

Small-scale

0.480

High

336672

SODC
Superoxide dismutase [Cu-Zn]

1

3

High-throughput

0.479

High

366081

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

405540

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

412710

KAPA
cAMP-dependent protein kinase type 1

1

2

Small-scale

0.479

High

425512

PROF
Profilin

1

2

High-throughput

0.479

High

439511

FUMH
Fumarate hydratase, mitochondrial

1

1

High-throughput

0.479

High

605327

HSP74
Heat shock protein SSA4

1

8

High-throughput

0.479

High

605968

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

607247

RFA1
Replication factor A protein 1

1

5

Small-scale

0.479

High

633111

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.479

High

680598

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

687342

EF2
Elongation factor 2

1

6

High-throughput

0.479

High

691018

HOG1
Mitogen-activated protein kinase HOG1

1

10

High-throughput

0.479

High

703574

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

710370

EDE1
EH domain-containing and endocytosis protein 1

1

2

Small-scale

0.479

High

713206

TOR1
Serine/threonine-protein kinase TOR1

1

1

Small-scale

0.479

High

713214

QOR
Probable quinone oxidoreductase

1

1

Small-scale

0.479

High

713217

RCK2
Serine/threonine-protein kinase RCK2

1

2

High-throughput

0.479

High

713219

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

1

High-throughput

0.479

High

713220

DNPEP
Aspartyl aminopeptidase 4

1

1

High-throughput

0.479

High

713224

TCPZ
T-complex protein 1 subunit zeta

1

7

High-throughput

0.479

High

713225

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

713228

RSP5
E3 ubiquitin-protein ligase RSP5

1

7

High-throughput

0.479

High

713229

SERA
D-3-phosphoglycerate dehydrogenase 1

1

4

Small-scale

0.479

High

713238

OTU1
Ubiquitin thioesterase OTU1

1

3

High-throughput

0.479

High

713245

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

713253

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

713258

TOM1
E3 ubiquitin-protein ligase TOM1

1

7

High-throughput

0.479

High

713261

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

713266

SUB2
ATP-dependent RNA helicase SUB2

1

5

Small-scale

0.479

High

713267

FRA1
Putative Xaa-Pro aminopeptidase FRA1

1

1

High-throughput

0.479

High

713278

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

336215

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.458

High

383058

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

389264

HXKA
Hexokinase-1

1

0

Small-scale

0.458

High

402927

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.458

High

407836

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413424

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

425616

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

425864

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

470974

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

472122

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

482183

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

604979

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

631785

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

688187

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

700325

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

704225

BUD2
Inhibitory regulator protein BUD2/CLA2

1

0

Small-scale

0.458

High

706186

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

713208

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

713212

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.458

High

713215

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

713218

RS20
Small ribosomal subunit protein uS10

1

0

Small-scale

0.458

High

713221

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

713226

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

713227

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

713235

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

713242

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

713248

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.458

High

713251

DAK1
Dihydroxyacetone kinase 1

1

0

Small-scale

0.458

High

713269

SGO1
Shugoshin

1

0

High-throughput

0.458

High

713273

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

713223

SEC31
Protein transport protein SEC31

1

7

High-throughput

0.457

High

648136

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.445

High

713232

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.445

High

557988

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

Small-scale

0.437

High

661844

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

705873

IXR1
Intrastrand cross-link recognition protein

1

6

Small-scale

0.437

High

713216

YB8A
Putative uncharacterized protein YBR285W

1

1

Small-scale

0.437

High

713249

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

713250

ORC1
Origin recognition complex subunit 1

1

4

High-throughput

0.437

High

713257

YMZ2
WD repeat-containing protein YMR102C

1

10

Small-scale

0.437

High

713270

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

713274

HOSM
Homocitrate synthase, mitochondrial

1

1

Small-scale

0.437

High

713276

ERV2
FAD-linked sulfhydryl oxidase ERV2

1

1

High-throughput

0.437

High

392381

H2A2
Histone H2A.2

1

3

High-throughput

0.407

High

713213

TAF5
Transcription initiation factor TFIID subunit 5

1

6

High-throughput

0.407

High

713230

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

2

High-throughput

0.407

High

375346

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

High-throughput

0.305

High

713240

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

High-throughput

0.279

Low

632525

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.261

Low

701200

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

713265

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.261

Low

713277

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.261

Low

568116

TPM1
Tropomyosin-1

1

0

Small-scale

0.249

Low

633845

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

713209

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

713241

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

713243

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

713260

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

713264

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

713275

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

713222

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

713234

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.232

Low

713244

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.232

Low

713255

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.232

Low

713272

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.232

Low

713279

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024