Protein: AKL1
Serine/threonine-protein kinase AKL1 (EC 2.7.11.1)

Gene: AKL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 142
UniProt ID: P38080

Gene Ontology (top 5):
GO:0000147 - actin cortical patch assembly
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005628 - prospore membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366155

HSP82
ATP-dependent molecular chaperone HSP82

3

20

High-throughput

0.827

High

710372

EDE1
EH domain-containing and endocytosis protein 1

2

15

High-throughput

0.799

High

743908

FPK1
Flippase kinase 1

2

18

Small-scale

0.778

High

477616

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

2

11

High-throughput

0.768

High

743878

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

9

High-throughput

0.762

High

743867

AKL1
Serine/threonine-protein kinase AKL1

1

18

High-throughput

0.698

High

664783

BMH1
Protein BMH1

4

20

High-throughput

0.694

High

584715

CSK22
Casein kinase II subunit alpha'

1

19

High-throughput

0.691

High

623464

KPC1
Protein kinase C-like 1

1

19

High-throughput

0.691

High

648149

KCC1
Calcium/calmodulin-dependent protein kinase I

1

15

High-throughput

0.691

High

743883

PRK1
Actin-regulating kinase PRK1

1

17

High-throughput

0.691

High

743911

ARK1
Actin-regulating kinase 1

1

18

High-throughput

0.691

High

409637

KAPC
cAMP-dependent protein kinase type 3

1

19

High-throughput

0.647

High

412972

KAPB
cAMP-dependent protein kinase type 2

1

15

High-throughput

0.647

High

416775

CDC31
Cell division control protein 31

1

14

High-throughput

0.647

High

743869

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

20

High-throughput

0.647

High

743870

MIP6
RNA-binding protein MIP6

1

3

High-throughput

0.647

High

743894

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

17

High-throughput

0.647

High

743909

JJJ1
J protein JJJ1

1

6

High-throughput

0.647

High

743910

CRZ1
Transcriptional regulator CRZ1

1

1

High-throughput

0.647

High

743923

VHS1
Serine/threonine-protein kinase VHS1

1

19

High-throughput

0.647

High

691027

HOG1
Mitogen-activated protein kinase HOG1

1

18

Small-scale

0.621

High

743874

KOG1
Target of rapamycin complex 1 subunit KOG1

1

5

High-throughput

0.621

High

697910

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

9

Small-scale

0.619

High

425619

KAPR
cAMP-dependent protein kinase regulatory subunit

1

7

High-throughput

0.618

High

543589

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.618

High

743919

SKI8
Antiviral protein SKI8

3

1

High-throughput

0.614

High

563949

SEC2
Rab guanine nucleotide exchange factor SEC2

2

2

High-throughput

0.602

High

743872

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.586

High

367974

EF1A
Elongation factor 1-alpha

2

2

High-throughput

0.584

High

490967

HSP71
Heat shock protein SSA1

2

13

High-throughput

0.584

High

630764

RHEB
Rheb-like protein RHB1

1

10

High-throughput

0.579

High

648369

NSR1
Nuclear localization sequence-binding protein

1

2

High-throughput

0.579

High

690613

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

4

High-throughput

0.575

High

743875

SET5
Histone-lysine N-methyltransferase SET5

2

0

Small-scale

0.569

High

477237

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

16

High-throughput

0.553

High

493745

HSP72
Heat shock protein SSA2

2

13

High-throughput

0.552

High

511009

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.552

High

629714

STE50
Protein STE50

2

0

High-throughput

0.551

High

675980

XPO1
Exportin-1

1

3

High-throughput

0.536

High

692220

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

8

High-throughput

0.536

High

704775

SLA2
Protein SLA2

1

12

High-throughput

0.536

High

743897

TRM9
tRNA

1

0

High-throughput

0.518

High

425074

SYH
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

341092

CBPY
Carboxypeptidase Y

1

2

High-throughput

0.501

High

410361

SC160
Protein SCP160

1

4

High-throughput

0.501

High

472564

YH11A
Transposon Ty1-H Gag polyprotein

1

2

High-throughput

0.501

High

549725

STI1
Heat shock protein STI1

1

4

High-throughput

0.501

High

562220

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

2

High-throughput

0.501

High

648311

GYS2
Glycogen [starch] synthase isoform 2

1

2

High-throughput

0.501

High

694532

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.501

High

733790

RNZ
Ribonuclease Z

1

1

High-throughput

0.501

High

743873

AP18A
Clathrin coat assembly protein AP180A

1

12

High-throughput

0.501

High

743876

TCPZ
T-complex protein 1 subunit zeta

1

9

High-throughput

0.501

High

743887

MVP1
Sorting nexin MVP1

1

1

High-throughput

0.501

High

743890

LSB3
LAS seventeen-binding protein 3

1

7

High-throughput

0.501

High

743893

ALY2
Arrestin-related trafficking adapter 3

1

3

High-throughput

0.501

High

743898

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.501

High

743904

PDK2
[Pyruvate dehydrogenase

1

1

High-throughput

0.501

High

743926

YM54
Uncharacterized protein YMR196W

1

1

High-throughput

0.501

High

743928

DCE
Glutamate decarboxylase

1

1

High-throughput

0.501

High

743931

ENT2
Epsin-2

1

5

High-throughput

0.501

High

743932

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.501

High

743886

SA185
SIT4-associating protein SAP185

1

3

High-throughput

0.489

High

389078

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.480

High

411234

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.480

High

423453

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.480

High

426490

TRPD
Anthranilate phosphoribosyltransferase

1

0

High-throughput

0.480

High

439710

MET2
Homoserine O-acetyltransferase

1

0

High-throughput

0.480

High

578241

ART10
Arrestin-related trafficking adapter 10

1

0

High-throughput

0.480

High

710486

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.480

High

743871

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.480

High

743880

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

743889

ATG18
Autophagy-related protein 18

1

0

High-throughput

0.480

High

743892

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.480

High

743922

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.480

High

743927

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.480

High

743930

FSH2
Family of serine hydrolases 2

1

0

High-throughput

0.480

High

743935

AB140
tRNA(Thr)

1

0

High-throughput

0.480

High

743937

GRE1
Protein GRE1

1

0

High-throughput

0.480

High

743939

RIB2
Bifunctional protein RIB2 [Includes: tRNA pseudouridine(32) synthase, cytoplasmic

1

0

High-throughput

0.480

High

448201

F16P
Fructose-1,6-bisphosphatase

1

1

Small-scale

0.479

High

712903

BMH2
Protein BMH2

1

20

High-throughput

0.479

High

715270

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

2

High-throughput

0.479

High

743879

GDI1
Rab GDP-dissociation inhibitor

1

1

High-throughput

0.479

High

743940

CMR1
DNA damage-binding protein CMR1

1

4

High-throughput

0.479

High

743907

HST1
NAD-dependent protein deacetylase HST1

1

5

High-throughput

0.470

High

627603

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.458

High

733012

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.458

High

743896

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

743912

UBX4
UBX domain-containing protein 4

1

0

High-throughput

0.458

High

743921

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.458

High

743924

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

619351

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.457

High

653477

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

2

High-throughput

0.457

High

692758

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.457

High

693845

SRP40
Suppressor protein SRP40

1

2

High-throughput

0.457

High

713189

SCD5
Protein SCD5

1

1

High-throughput

0.457

High

743877

RS26B
Small ribosomal subunit protein eS26B

1

1

High-throughput

0.457

High

743884

UTP25
U3 small nucleolar RNA-associated protein 25

1

2

High-throughput

0.457

High

743900

MALX3
Oligo-1,6-glucosidase IMA1

1

2

High-throughput

0.457

High

743903

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.457

High

743906

6PGD2
6-phosphogluconate dehydrogenase, decarboxylating 2

1

1

High-throughput

0.457

High

743916

NUP49
Nucleoporin NUP49/NSP49

1

3

High-throughput

0.457

High

743929

IVY1
Protein IVY1

1

1

High-throughput

0.457

High

424472

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

478126

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.445

High

540564

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

640916

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.445

High

743881

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

743882

6P21
6-phosphofructo-2-kinase 1

1

5

High-throughput

0.445

High

743902

HOS2
Probable histone deacetylase HOS2

1

8

High-throughput

0.445

High

336223

CCPR
Cytochrome c peroxidase, mitochondrial

1

2

High-throughput

0.437

High

356420

H4
Histone H4

1

1

High-throughput

0.437

High

448495

PRTB
Cerevisin

1

2

High-throughput

0.437

High

558016

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

661994

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

743499

HMT1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.437

High

743888

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

High-throughput

0.437

High

743899

SAP4
SIT4-associating protein SAP4

1

3

High-throughput

0.437

High

743913

H3
Histone H3

1

5

High-throughput

0.437

High

743915

NUM1
Nuclear migration protein NUM1

1

18

High-throughput

0.437

High

743891

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.407

High

743933

BRE1
E3 ubiquitin-protein ligase BRE1

1

10

High-throughput

0.407

High

743920

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

635504

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.261

Low

743895

PXP2
Peroxisomal protein 2

1

0

High-throughput

0.261

Low

743905

YG1D
Probable transcriptional regulatory protein HAH1

1

0

High-throughput

0.261

Low

743917

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.261

Low

743918

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

0

High-throughput

0.261

Low

743934

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

1

0

High-throughput

0.261

Low

743938

SSF2
Ribosome biogenesis protein SSF2

1

0

High-throughput

0.261

Low

715875

MAC1
Metal-binding activator 1

1

0

High-throughput

0.249

Low

716407

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

743759

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

743868

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

743885

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

743901

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.249

Low

743925

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

743936

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

743914

YD413
Putative uncharacterized protein YDR413C

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024