Protein: SUM1
Suppressor of mar1-1 protein (SUM1-1 protein)

Gene: SUM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P46676

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003688 - DNA replication origin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805183

HST1
NAD-dependent protein deacetylase HST1

6

1

Small-scale

0.729

High

805195

RFM1
Repression factor of MSEs protein 1

4

0

Small-scale

0.658

High

805178

SUM1
Suppressor of mar1-1 protein

2

0

Small-scale

0.559

High

805180

ORC5
Origin recognition complex subunit 5

2

0

Small-scale

0.559

High

494286

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

805185

H3
Histone H3

2

0

High-throughput

0.547

High

743580

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.530

High

511783

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

565276

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.513

High

693718

IME2
Meiosis induction protein kinase IME2/SME1

1

0

Small-scale

0.480

High

355927

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

416230

SIR2
NAD-dependent histone deacetylase SIR2

1

1

Small-scale

0.479

High

516886

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.460

High

702678

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

805181

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.460

High

356556

H4
Histone H4

1

0

High-throughput

0.458

High

392482

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

549621

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

558123

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

589029

PYRC
Dihydroorotase

1

0

High-throughput

0.458

High

606053

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

607300

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

662591

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

698721

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.458

High

698858

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

716281

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

755779

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

Small-scale

0.458

High

775763

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

805179

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

805184

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

805188

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

805189

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.458

High

805190

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

805192

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

805193

SGO1
Shugoshin

1

0

High-throughput

0.458

High

805194

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

805198

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

355530

H2B1
Histone H2B.1

1

1

High-throughput

0.445

High

491631

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

628211

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

694961

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

733262

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

761256

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

805191

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

715290

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.437

High

366503

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

515066

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

609107

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

633334

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

689902

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

691909

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

772292

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.426

High

805187

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

805197

RLF2
Chromatin assembly factor 1 subunit p90

1

0

High-throughput

0.426

High

805186

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.407

High

797810

LSB3
LAS seventeen-binding protein 3

1

0

High-throughput

0.282

High

752799

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

805182

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

336250

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

404624

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

637146

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

0

High-throughput

0.249

Low

743780

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

744322

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

745506

KMO
Kynurenine 3-monooxygenase

1

0

High-throughput

0.249

Low

748152

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

765611

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.249

Low

805196

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.249

Low

764829

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.232

Low

805146

STU2
Protein STU2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024